ES2060095T3 - Nuevas imidazobenzodiazepinas y sus sales, procedimiento de preparacion, aplicacion como medicamentos y composiciones que los contienen. - Google Patents
Nuevas imidazobenzodiazepinas y sus sales, procedimiento de preparacion, aplicacion como medicamentos y composiciones que los contienen.Info
- Publication number
- ES2060095T3 ES2060095T3 ES90401151T ES90401151T ES2060095T3 ES 2060095 T3 ES2060095 T3 ES 2060095T3 ES 90401151 T ES90401151 T ES 90401151T ES 90401151 T ES90401151 T ES 90401151T ES 2060095 T3 ES2060095 T3 ES 2060095T3
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- carbon atoms
- group
- salts
- imidazobenzodiazepines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000000755 benzodiazepine receptor inverse stimulating agent Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
LA INVENCION SE REFIERE A NUEVAS IMIDAZOBENZODIACEPINAS DE FORMULA (I), EN LA QUE LOS SUSTITUYENTES R1 REPRESENTAN UN ALCOHILO C1-C3 O FORMAN JUNTOS UN PUENTE ALQUILENO C2-C5; X E Y REPRESENTAN O O S; R2 ES HIDROGENO, ALCOHILO C1-C3; R3 ES HIDROGENO, ALCOHILO C1-C5, FENILO O FENILO SUSTITUIDO; W ES O O S; R4 Y R5 REPRESENTAN HIDROGENO, HALOGENO, HIDROXI, ALCOHILO O ALCOXI C1-C3 O CF3, ENTENDIENDO QUE CUANDO CADA R1 REPRESENTA UN ALCOHILO, X E Y SON IGUALES, ASI COMO SALES DE ADICION CON ACIDOS MINERALES U ORGANICOS, SU OBTENCION, SU APLICACION COMO MEDICAMENTOS, ESPECIALMENTE EN EL TRATAMIENTO DE PROBLEMAS DE LA MEMORIA, EN GERIATRIA Y COMO TRANQUILIZANTES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898909700A GB8909700D0 (en) | 1989-04-27 | 1989-04-27 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2060095T3 true ES2060095T3 (es) | 1994-11-16 |
Family
ID=10655860
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90401151T Expired - Lifetime ES2060095T3 (es) | 1989-04-27 | 1990-04-27 | Nuevas imidazobenzodiazepinas y sus sales, procedimiento de preparacion, aplicacion como medicamentos y composiciones que los contienen. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5017574A (es) |
| EP (1) | EP0395527B1 (es) |
| JP (1) | JPH0363279A (es) |
| AT (1) | ATE111465T1 (es) |
| CA (1) | CA2015569A1 (es) |
| DE (1) | DE69012407T2 (es) |
| DK (1) | DK0395527T3 (es) |
| ES (1) | ES2060095T3 (es) |
| GB (1) | GB8909700D0 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2015336A1 (en) * | 1989-05-19 | 1990-11-19 | F. Hoffmann-La Roche Ag | Imidazodiazepines for the treatment of neurological symptoms |
| GB8927928D0 (en) * | 1989-12-11 | 1990-02-14 | Roussel Lab Ltd | Chemical compounds |
| GB9022758D0 (en) * | 1990-10-19 | 1990-12-05 | Roussel Lab Ltd | Hetero-imidazodiazepine derivatives |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1143728A (en) * | 1979-10-04 | 1983-03-29 | Max Gerecke | Imidazodiazepine derivatives |
| FI880814A7 (fi) * | 1987-03-10 | 1988-09-11 | Hoffmann La Roche | Imidazodiazepin-derivat. |
| GB8720414D0 (en) * | 1987-08-28 | 1987-10-07 | Roussel Lab Ltd | Chemical compounds |
-
1989
- 1989-04-27 GB GB898909700A patent/GB8909700D0/en active Pending
-
1990
- 1990-04-26 US US07/516,194 patent/US5017574A/en not_active Expired - Fee Related
- 1990-04-26 CA CA002015569A patent/CA2015569A1/en not_active Abandoned
- 1990-04-26 JP JP2108988A patent/JPH0363279A/ja active Pending
- 1990-04-27 DK DK90401151.7T patent/DK0395527T3/da active
- 1990-04-27 ES ES90401151T patent/ES2060095T3/es not_active Expired - Lifetime
- 1990-04-27 EP EP90401151A patent/EP0395527B1/fr not_active Expired - Lifetime
- 1990-04-27 DE DE69012407T patent/DE69012407T2/de not_active Expired - Fee Related
- 1990-04-27 AT AT90401151T patent/ATE111465T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69012407D1 (de) | 1994-10-20 |
| DE69012407T2 (de) | 1995-02-09 |
| DK0395527T3 (da) | 1995-02-20 |
| CA2015569A1 (en) | 1990-10-27 |
| EP0395527A1 (fr) | 1990-10-31 |
| US5017574A (en) | 1991-05-21 |
| GB8909700D0 (en) | 1989-06-14 |
| ATE111465T1 (de) | 1994-09-15 |
| EP0395527B1 (fr) | 1994-09-14 |
| JPH0363279A (ja) | 1991-03-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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