[go: up one dir, main page]

ES2166840T3 - 6-r-1,3,4-tiadiacin-2-aminas sustituidas, su empleo como agentes anestesicos, cardiovasculares e hipometabolicos, y preparado farmaceutico que los contiene. - Google Patents

6-r-1,3,4-tiadiacin-2-aminas sustituidas, su empleo como agentes anestesicos, cardiovasculares e hipometabolicos, y preparado farmaceutico que los contiene.

Info

Publication number
ES2166840T3
ES2166840T3 ES95944776T ES95944776T ES2166840T3 ES 2166840 T3 ES2166840 T3 ES 2166840T3 ES 95944776 T ES95944776 T ES 95944776T ES 95944776 T ES95944776 T ES 95944776T ES 2166840 T3 ES2166840 T3 ES 2166840T3
Authority
ES
Spain
Prior art keywords
cardiovascular
amines
tiadiacin
anesthetic
employment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95944776T
Other languages
English (en)
Inventor
Oleg Nikolaevich Chupakhin
Larisa Petrovna Sidorova
Emma Afanasievna Tarakhty
Antonina Petrovna Novikova
Natalya Mikhailovna Perova
Valentin Antonovich Vinogradov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LIGAND NTP TOO
N T PREDPR LIGAND OBSCHESTVO S
Original Assignee
LIGAND NTP TOO
N T PREDPR LIGAND OBSCHESTVO S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LIGAND NTP TOO, N T PREDPR LIGAND OBSCHESTVO S filed Critical LIGAND NTP TOO
Application granted granted Critical
Publication of ES2166840T3 publication Critical patent/ES2166840T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

LA INVENCION SE REFIERE A 6 - R - 1,3,4 - TADIAZIN - 2 -AMINAS, REPRESENTADAS POR LA SIGUIENTE FORMULA GENERAL: DONDE AR ES FENILO OPCIONALMENTE SUSTITUIDO POR UNO O MAS ATOMOS DE CLORO, BROMO, GRUPOS ALCOXI C 1 - C 4 O ALQUILO C 1 - C 4 ; R 1 Y R 2 SON CADA UNO INDEPENDIENTEMENTE UN ATOMO DE HIDROGENO O UNA FRACCION DE ALQUILO C 1 - C 4 ; Y $ 3 Y R 4 SE SELECCIONAN INDEPENDIENTEMENTE ENTRE GRUPOS ALQUILO C 1 - C 4 , ASI COMO LAS S ALES FARMACEUTICAMENTE ACEPTABLES DE DICHOS COMPUESTOS, LA UTILIZACION DE LOS MISMOS COMO AGENTES ANESTESICOS, CARDIOVASCULARES E HIPOMETABOLICOS Y LAS COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.
ES95944776T 1995-12-28 1995-12-28 6-r-1,3,4-tiadiacin-2-aminas sustituidas, su empleo como agentes anestesicos, cardiovasculares e hipometabolicos, y preparado farmaceutico que los contiene. Expired - Lifetime ES2166840T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/RU1995/000285 WO1997024354A1 (en) 1995-12-28 1995-12-28 Substituted 6-r-1,3,4-thiadiazine-2-amines, the use thereof as anaesthetising, cardiovascular and hypometabolic agents, and a pharmaceutical composition containing them

Publications (1)

Publication Number Publication Date
ES2166840T3 true ES2166840T3 (es) 2002-05-01

Family

ID=20129973

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95944776T Expired - Lifetime ES2166840T3 (es) 1995-12-28 1995-12-28 6-r-1,3,4-tiadiacin-2-aminas sustituidas, su empleo como agentes anestesicos, cardiovasculares e hipometabolicos, y preparado farmaceutico que los contiene.

Country Status (8)

Country Link
US (1) US6117867A (es)
EP (1) EP0877026B1 (es)
JP (1) JP2000515117A (es)
AT (1) ATE207918T1 (es)
AU (1) AU5127996A (es)
DE (1) DE69523640T2 (es)
ES (1) ES2166840T3 (es)
WO (1) WO1997024354A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2259371C2 (ru) * 2003-05-05 2005-08-27 Общество с ограниченной ответственностью Научно-технологическое предприятие "Лиганд" Замещенные 5r1,6r2 1,3,4-тиадиазин-2 амины и содержащие их фармацевтические композиции в качестве фармакологически активных средств, обладающих антикоагулянтным и антиагрегантным действием
WO2014164200A1 (en) * 2013-03-13 2014-10-09 Avon Products, Inc Tyrosinase inhibitors

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE288824C (es) *
DE228248C (es) *
DE220311C (es) *
US3956311A (en) * 1970-08-29 1976-05-11 Agfa-Gevaert, A.G. Process for the preparation of 3-anilino-pyrazolones-(5)
JPS4988889A (es) * 1972-12-29 1974-08-24
US4272532A (en) * 1979-09-04 1981-06-09 Richardson-Merrell Inc. 5-(Optionally substituted phenyl)-6H-1,3,4-thiadiazine-2-amines
ZA804555B (en) * 1979-09-04 1981-09-30 Richardson Merrell Inc 5-(optionally substituted phenyl)-6h-1,3,4-thiadiazine-2-amines
US4289767A (en) * 1979-09-04 1981-09-15 Richardson-Merrell Inc. 5-(Chlorophenyl)-6H-1,3,4-thiadiazine-2-amines
US4309426A (en) * 1979-09-04 1982-01-05 Richardson-Merrell Inc. Muscle-relaxant 1,3,4-thiadiazin-2-amines
DE3042295A1 (de) * 1980-11-08 1982-06-09 Richardson-Merrell Inc., Wilton, Conn. Substituierte 6h-1,3,4-thiadiazin-2-amine, verfahren zu ihrer herstellung und ihre verwendung
FR2493844A1 (fr) * 1980-11-12 1982-05-14 Richardson Merrell Inc Nouvelles 5-(phenyl facultativement substitue)-6h-1,3,4-thiadiazine-2-amines, utiles notamment comme relaxants musculaires, et leur procede de preparation
CA1199027A (en) * 1981-11-12 1986-01-07 Stuart D. Mills Heterocyclic derivatives of pyridazinone, thiadiazinone, oxadiazinone and triazinone
DE3517845A1 (de) * 1985-05-17 1986-11-20 Bayer Ag, 5090 Leverkusen Benzolactamsultame
DE3702756A1 (de) * 1987-01-30 1988-08-11 Hoechst Ag 5-(3-alkyl-5-tert.butyl-4-hydroxyphenyl)-2- amino-6h-1,3,4-thiadiazine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung
GB2215206B (en) * 1988-02-29 1991-07-03 Farmos Oy 4-substituted imidazole derivatives useful in perioperative care
US5021413B1 (en) * 1988-08-24 1994-12-13 Sankyo Co Analgesic thiomorpholins, their preparation, and pharmaceutical compositions containing them
SU1726478A1 (ru) * 1990-04-09 1992-04-15 Уральский политехнический институт им.С.М.Кирова 2-Гексаметиленимино-5-(4-бромфенил)-6Н-1,3,4-тиадиазин гидроиодид, обладающий контрацептивной активностью
DE4141218A1 (de) * 1991-12-13 1993-06-17 Luitpold Werk Chem Pharm Thiadiazincarbonsaeureamidderivate, verfahren zu ihrer herstellung und arzneimittel
JP3160787B2 (ja) * 1993-03-03 2001-04-25 株式会社アイホー 連続式米飯冷却装置

Also Published As

Publication number Publication date
US6117867A (en) 2000-09-12
EP0877026B1 (en) 2001-10-31
JP2000515117A (ja) 2000-11-14
EP0877026A1 (en) 1998-11-11
ATE207918T1 (de) 2001-11-15
AU5127996A (en) 1997-07-28
DE69523640T2 (de) 2002-11-21
DE69523640D1 (de) 2001-12-06
WO1997024354A1 (en) 1997-07-10
EP0877026A4 (en) 1999-04-07

Similar Documents

Publication Publication Date Title
MX9203122A (es) Compuestos analogos de distamicina a y composiciones farmaceuticas que los contienen.
DK490288D0 (da) Hidtil ukendte forbindelser
FI851069L (fi) 3-substituerade 2-oxidol-1 -karboxiamider saosom analgetiska och anti-inflammatoriska aemnen.
DE69304057D1 (de) Indole fungizide
SE9002206D0 (sv) New compounds
DK0409406T3 (da) Arylsubstituerede aminderivater, der er anvendelige ved cancerterapi
NO306510B1 (no) Androsteroner, anvendelse derav og farmasöytisk formulering
AR007108A1 (es) Agentes antitumorales y antivirales alquilantes, procedimiento para su preparacion, utilizacion de los mismos para la fabricacion de un medicamento y composicion farmaceutica que contiene a dichos agentes.
EE04496B1 (et) Tetrahüdro-gamma-karboliinid, nende valmistamine ja kasutamine ravimina ning neid sisaldavad kompositsioonid
ES2032217T3 (es) Nuevos derivados n-(23-vinblastinoil del acido 1-amino-metilfosfonico, sus procedimientos de preparacion y las composiciones farmaceuticas que los contienen.
MX9203712A (es) Derivados de benzanilida y composiciones farmaceuticas que los contienen.
ES2166840T3 (es) 6-r-1,3,4-tiadiacin-2-aminas sustituidas, su empleo como agentes anestesicos, cardiovasculares e hipometabolicos, y preparado farmaceutico que los contiene.
ES2118343T3 (es) Nuevos derivados de 2-(1h)-quinoleinona, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
ATE86117T1 (de) Zusammensetzung gegen leberkrankheiten.
DE69005318D1 (de) 1,8-Benzonaphthyridinderivate, ihre Herstellung und diese enthaltende Zusammensetzungen.
NO166125C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive aroyl-substituerte dihydro-1,4-tiaziner.
ATE134607T1 (de) Tetrahydronaphtalenderivate, ihre herstellung und ihre therapeutische verwendung
ATE109485T1 (de) Derivate von n-(vincristinyl-23) und n- (noranhydro-5-vinblastinyl-23) von amino-1- methylphosphonsäure, ihre verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen.
ES2060095T3 (es) Nuevas imidazobenzodiazepinas y sus sales, procedimiento de preparacion, aplicacion como medicamentos y composiciones que los contienen.
ES2172606T3 (es) 6-h-1,3,4-tiadiazin-2-aminas, su uso como agentes anestesicos, cardiovasculares e hipometabolicos, y una composicion farmaceutica que las contiene.
MX9702941A (es) Compuestos de di-ter - butilfenol que tiene una porcion heterociclica, utiles como agentes anti-inflamatorios.