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MX2023000192A - Particulas conjugadas con peptidos. - Google Patents

Particulas conjugadas con peptidos.

Info

Publication number
MX2023000192A
MX2023000192A MX2023000192A MX2023000192A MX2023000192A MX 2023000192 A MX2023000192 A MX 2023000192A MX 2023000192 A MX2023000192 A MX 2023000192A MX 2023000192 A MX2023000192 A MX 2023000192A MX 2023000192 A MX2023000192 A MX 2023000192A
Authority
MX
Mexico
Prior art keywords
particles
peptide conjugated
conjugated particles
peptide
plg
Prior art date
Application number
MX2023000192A
Other languages
English (en)
Inventor
Stephen D Miller
Jonathan Woon Teck Yap
Derrick Mccarthy
Daniel R Getts
Shea Lonnie D
Original Assignee
Univ Northwestern
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52468804&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2023000192(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Northwestern filed Critical Univ Northwestern
Publication of MX2023000192A publication Critical patent/MX2023000192A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6927—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
    • A61K47/6929—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle
    • A61K47/6931—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer
    • A61K47/6935—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer the polymer being obtained otherwise than by reactions involving carbon to carbon unsaturated bonds, e.g. polyesters, polyamides or polyglycerol
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    • A61K47/6931—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer
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    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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Abstract

La presente invención proporciona composiciones que comprenden partículas biodegradables con superficie funcionalizada que comprenden un antígeno encapsulado o uno o más epítopos antigénicos, en donde la partícula tiene un potencial zeta negativo de - 30 mV a -80 mV. En una modalidad particular de la invención, la partícula es una partícula de poliestireno, una partícula de poliestireno carboxilado, una partícula de sulfuro de polipropileno estabilizado PLURIONICS, una partícula de poli (ácido láctico-co-glicólico), una partícula de poli (ácido láctico) (PLA), o una partícula de poli (ácido glicólico) (PGA). En otra modalidad particular de la invención, el antígeno comprende un antígeno autoinmunitario, un antígeno expresado en un tejido que se trasplantará a un sujeto, o una enzima para terapia de reemplazo de enzimas.
MX2023000192A 2013-08-13 2016-02-12 Particulas conjugadas con peptidos. MX2023000192A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361865389P 2013-08-13 2013-08-13
US201361869279P 2013-08-23 2013-08-23
US201361887112P 2013-10-04 2013-10-04

Publications (1)

Publication Number Publication Date
MX2023000192A true MX2023000192A (es) 2023-02-09

Family

ID=52468804

Family Applications (5)

Application Number Title Priority Date Filing Date
MX2016001931A MX372849B (es) 2013-08-13 2014-08-13 Partículas conjugadas con péptidos.
MX2023000194A MX2023000194A (es) 2013-08-13 2016-02-12 Particulas conjugadas con peptidos.
MX2023000192A MX2023000192A (es) 2013-08-13 2016-02-12 Particulas conjugadas con peptidos.
MX2020007079A MX2020007079A (es) 2013-08-13 2016-02-12 Particulas conjugadas con peptidos.
MX2020004799A MX2020004799A (es) 2013-08-13 2016-02-12 Particulas conjugadas con peptidos.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2016001931A MX372849B (es) 2013-08-13 2014-08-13 Partículas conjugadas con péptidos.
MX2023000194A MX2023000194A (es) 2013-08-13 2016-02-12 Particulas conjugadas con peptidos.

Family Applications After (2)

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US9522180B2 (en) 2016-12-20
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