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MX2018016361A - Derivado de piranocromenil fenol opticamente activo y composición farmacéutica que comprende el mismo. - Google Patents

Derivado de piranocromenil fenol opticamente activo y composición farmacéutica que comprende el mismo.

Info

Publication number
MX2018016361A
MX2018016361A MX2018016361A MX2018016361A MX2018016361A MX 2018016361 A MX2018016361 A MX 2018016361A MX 2018016361 A MX2018016361 A MX 2018016361A MX 2018016361 A MX2018016361 A MX 2018016361A MX 2018016361 A MX2018016361 A MX 2018016361A
Authority
MX
Mexico
Prior art keywords
pharmaceutical composition
same
optically active
phenol derivative
pyranochromenyl phenol
Prior art date
Application number
MX2018016361A
Other languages
English (en)
Other versions
MX393450B (es
Inventor
Wook Chung Jin
Ku Yoo Sang
Suk KANG Ku
Young Kim Jin
Geun Jo In
Ho IM Jeong
Young Kim Ji
Original Assignee
Glaceum Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaceum Inc filed Critical Glaceum Inc
Publication of MX2018016361A publication Critical patent/MX2018016361A/es
Publication of MX393450B publication Critical patent/MX393450B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere a derivados de piranocromenilfenol que tienen diferentes eficacias dependiendo de la dirección de la actividad óptica y una composición farmacéutica que los incluye, y en los derivados de piranocromenilfenol, un enantiómero R tiene una excelente eficacia antidiabética al suprimir un aumento en el azúcar en sangre y un enantiómero S tiene una excelente eficacia anti-obesidad al suprimir el aumento del peso corporal.
MX2018016361A 2016-06-29 2017-06-29 Derivado de piranocromenil fenol opticamente activo y composición farmacéutica que comprende el mismo. MX393450B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20160081674 2016-06-29
PCT/KR2017/006863 WO2018004263A1 (ko) 2016-06-29 2017-06-29 광학 활성 피라노크로메닐페놀 유도체 및 그를 포함하는 약학적 조성물

Publications (2)

Publication Number Publication Date
MX2018016361A true MX2018016361A (es) 2019-09-16
MX393450B MX393450B (es) 2025-03-24

Family

ID=60787377

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018016361A MX393450B (es) 2016-06-29 2017-06-29 Derivado de piranocromenil fenol opticamente activo y composición farmacéutica que comprende el mismo.

Country Status (17)

Country Link
US (2) US20190152984A1 (es)
EP (2) EP3480200B1 (es)
JP (2) JP2019520381A (es)
KR (1) KR102388965B1 (es)
CN (1) CN109476676B (es)
AU (1) AU2017287746B2 (es)
BR (1) BR112018077392A2 (es)
CA (1) CA3028954C (es)
DK (1) DK4023651T3 (es)
ES (2) ES2964146T3 (es)
IL (1) IL263826B2 (es)
MX (1) MX393450B (es)
PL (2) PL4023651T3 (es)
SG (1) SG11201811796SA (es)
TW (1) TWI731998B (es)
WO (1) WO2018004263A1 (es)
ZA (1) ZA201900121B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR109735A1 (es) * 2016-10-04 2019-01-16 Glaceum Inc Método para la síntesis de derivado de 3-fenil-2,3,4,8,9,10-hexahidropirano[2,3-f]cromeno e isómero óptico del mismo
KR20200105198A (ko) * 2019-02-28 2020-09-07 주식회사 글라세움 신경계 질환의 예방 또는 치료용 약학적 조성물
EP4353226A4 (en) 2021-06-08 2024-10-16 Glaceum, Inc. PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF DEGENERATIVE EYE DISEASES
KR20240078928A (ko) * 2022-11-28 2024-06-04 가톨릭대학교 산학협력단 침샘 오가노이드 안정화 및 침샘조직 재생 유도 조성물
KR20240113389A (ko) 2023-01-12 2024-07-22 주식회사 글라세움 퇴행성 골관절염의 예방 또는 치료용 약학적 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003037316A1 (en) * 2001-10-11 2003-05-08 Kaneka Corporation Peroxisome proliferator activated receptor ligands and process for producing the same
TW200513194A (en) * 2003-07-31 2005-04-16 Kaneka Corp Fat and oil processed composition for prevention and/or amelioration of life-style related disease
WO2007058480A1 (en) 2005-11-16 2007-05-24 Md Bioalpha Co., Ltd. Composition having effect on treatment and prevention of diseases syndrome treatment with glabridin
KR102344479B1 (ko) * 2013-12-24 2021-12-29 주식회사 글라세움 피라노크로메닐페놀 유도체, 및 대사증후군 또는 염증 질환 치료용 약학 조성물
KR101742274B1 (ko) 2014-12-31 2017-06-01 주식회사 과학기술분석센타 소규모 상수시설 통합 관리 시스템의 수질 측정 장치
AR109735A1 (es) * 2016-10-04 2019-01-16 Glaceum Inc Método para la síntesis de derivado de 3-fenil-2,3,4,8,9,10-hexahidropirano[2,3-f]cromeno e isómero óptico del mismo

Also Published As

Publication number Publication date
CA3028954A1 (en) 2018-01-04
AU2017287746A1 (en) 2019-01-17
NZ749461A (en) 2020-08-28
JP7036871B2 (ja) 2022-03-15
WO2018004263A1 (ko) 2018-01-04
IL263826B2 (en) 2023-05-01
EP3480200B1 (en) 2022-10-19
JP2020186259A (ja) 2020-11-19
IL263826B1 (en) 2023-01-01
US11332475B2 (en) 2022-05-17
CN109476676B (zh) 2021-09-17
US20190152984A1 (en) 2019-05-23
ES2929931T3 (es) 2022-12-05
IL263826A (en) 2019-01-31
ES2964146T3 (es) 2024-04-04
BR112018077392A2 (pt) 2019-04-09
KR102388965B1 (ko) 2022-04-22
PL3480200T3 (pl) 2023-01-30
EP3480200A1 (en) 2019-05-08
CA3028954C (en) 2020-10-27
DK4023651T3 (da) 2023-11-20
EP4023651A1 (en) 2022-07-06
SG11201811796SA (en) 2019-02-27
JP2019520381A (ja) 2019-07-18
EP4023651B1 (en) 2023-09-13
PL4023651T3 (pl) 2024-02-19
US20210094967A1 (en) 2021-04-01
CN109476676A (zh) 2019-03-15
AU2017287746B2 (en) 2020-04-09
KR20180002539A (ko) 2018-01-08
ZA201900121B (en) 2023-04-26
MX393450B (es) 2025-03-24
TW201808961A (zh) 2018-03-16
TWI731998B (zh) 2021-07-01
EP3480200A4 (en) 2020-02-26

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