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MX2018014163A - Composiciones de nucleotido marcados y metodos para el secuenciamiento de acido nucleico. - Google Patents

Composiciones de nucleotido marcados y metodos para el secuenciamiento de acido nucleico.

Info

Publication number
MX2018014163A
MX2018014163A MX2018014163A MX2018014163A MX2018014163A MX 2018014163 A MX2018014163 A MX 2018014163A MX 2018014163 A MX2018014163 A MX 2018014163A MX 2018014163 A MX2018014163 A MX 2018014163A MX 2018014163 A MX2018014163 A MX 2018014163A
Authority
MX
Mexico
Prior art keywords
methods
nucleic acid
acid sequencing
labeled nucleotide
nucleotide compositions
Prior art date
Application number
MX2018014163A
Other languages
English (en)
Inventor
Reed Brian
Lackey Jeremy
M Rothberg Jonathan
Dodd David
Shi Xinghua
Huang Haidong
Original Assignee
Quantum Si Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quantum Si Inc filed Critical Quantum Si Inc
Publication of MX2018014163A publication Critical patent/MX2018014163A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/101—Modifications characterised by incorporating non-naturally occurring nucleotides, e.g. inosine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/197—Modifications characterised by incorporating a spacer/coupling moiety
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/30—Oligonucleotides characterised by their secondary structure
    • C12Q2525/301—Hairpin oligonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/103—Nucleic acid detection characterized by the use of physical, structural and functional properties luminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

Se proporcionan metodos de secuenciamiento de moleculas basadas en la duración de la luminiscencia y/o intensidades; en algunos aspectos, los metodos de secuenciamiento de acidos nucleicos implican determinar las vidas utiles de la luminiscencia y, opcionalmente, las intensidades de luminiscencia de una serie de nucleotidos marcados luminiscentemente incorporados durante una reaccion de secuenciamiento de acidos nucleicos; en algunos aspectos, la descripción proporciona composiciones que comprenden nucleotidos marcados luminiscentemente.
MX2018014163A 2016-05-20 2017-05-20 Composiciones de nucleotido marcados y metodos para el secuenciamiento de acido nucleico. MX2018014163A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662339790P 2016-05-20 2016-05-20
US201662426144P 2016-11-23 2016-11-23
PCT/US2017/033706 WO2017201514A1 (en) 2016-05-20 2017-05-20 Labeled nucleotide compositions and methods for nucleic acid sequencing

Publications (1)

Publication Number Publication Date
MX2018014163A true MX2018014163A (es) 2019-04-01

Family

ID=59021574

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018014163A MX2018014163A (es) 2016-05-20 2017-05-20 Composiciones de nucleotido marcados y metodos para el secuenciamiento de acido nucleico.

Country Status (11)

Country Link
US (2) US20170362651A1 (es)
EP (2) EP3458465B1 (es)
JP (2) JP7133473B2 (es)
KR (1) KR102425463B1 (es)
CN (1) CN109328192A (es)
AU (2) AU2017268466C1 (es)
BR (1) BR112018073378A2 (es)
CA (1) CA3025031A1 (es)
MX (1) MX2018014163A (es)
TW (1) TWI863886B (es)
WO (1) WO2017201514A1 (es)

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WO2019023257A1 (en) * 2017-07-24 2019-01-31 Quantum-Si Incorporated HIGH INTENSITY MARKED REAGENT COMPOSITIONS AND SEQUENCING METHODS
MX2021000470A (es) 2018-07-13 2021-06-23 Quantum Si Inc Etiquetas biconjugables y métodos de uso.
US11613772B2 (en) 2019-01-23 2023-03-28 Quantum-Si Incorporated High intensity labeled reactant compositions and methods for sequencing
JP2022551523A (ja) 2019-10-11 2022-12-09 クアンタム－エスアイ インコーポレイテッド 気相における表面修飾
EP4204584A4 (en) * 2020-09-21 2024-08-28 Quantum-si Incorporated METHODS FOR MINIMIZING PHOTODEGRADATION DURING NUCLEIC ACID AND PEPTIDE SEQUENCING
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Also Published As

Publication number Publication date
JP2022126734A (ja) 2022-08-30
TWI863886B (zh) 2024-12-01
JP7519157B2 (ja) 2024-07-19
CN109328192A (zh) 2019-02-12
AU2017268466C1 (en) 2022-04-07
WO2017201514A1 (en) 2017-11-23
EP4428528A2 (en) 2024-09-11
TW201742922A (zh) 2017-12-16
BR112018073378A2 (pt) 2019-03-06
AU2017268466A1 (en) 2018-11-29
AU2021290387A1 (en) 2022-02-03
AU2021290387B2 (en) 2024-02-01
EP3458465A1 (en) 2019-03-27
CA3025031A1 (en) 2017-11-23
JP2019523756A (ja) 2019-08-29
KR102425463B1 (ko) 2022-07-27
US20240035081A1 (en) 2024-02-01
EP3458465B1 (en) 2024-05-08
US20170362651A1 (en) 2017-12-21
EP4428528A3 (en) 2025-04-23
AU2017268466B2 (en) 2021-10-07
KR20190007495A (ko) 2019-01-22
JP7133473B2 (ja) 2022-09-08

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