MX2018003023A - Metodos de tratamiento de trastornos neurodegenerativos en una poblacion de pacientes particular. - Google Patents
Metodos de tratamiento de trastornos neurodegenerativos en una poblacion de pacientes particular.Info
- Publication number
- MX2018003023A MX2018003023A MX2018003023A MX2018003023A MX2018003023A MX 2018003023 A MX2018003023 A MX 2018003023A MX 2018003023 A MX2018003023 A MX 2018003023A MX 2018003023 A MX2018003023 A MX 2018003023A MX 2018003023 A MX2018003023 A MX 2018003023A
- Authority
- MX
- Mexico
- Prior art keywords
- patient population
- methods
- treatment
- particular patient
- neurodegenerative disorders
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Aquí se describen métodos para tratar, mejorar y/o prevenir la enfermedad de Alzheimer en una población de pacientes específica utilizando tramiprosato, ácido valil-3-amino-1-propansulfónico o una sal farmacéuticamente aceptable del mismo basado en una combinación de estado APOE4 y gravedad de la enfermedad.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562216404P | 2015-09-10 | 2015-09-10 | |
| US201662290287P | 2016-02-02 | 2016-02-02 | |
| US201662302027P | 2016-03-01 | 2016-03-01 | |
| US201662365809P | 2016-07-22 | 2016-07-22 | |
| PCT/US2016/051091 WO2017044840A1 (en) | 2015-09-10 | 2016-09-09 | Methods of treating neurodegenerative disorders in a particular patient population |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2018003023A true MX2018003023A (es) | 2018-06-06 |
| MX392677B MX392677B (es) | 2025-03-24 |
Family
ID=58240195
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018003023A MX392677B (es) | 2015-09-10 | 2016-09-09 | Composiciones para usarse en el tratamiento de trastornos neurodegenerativos en una población particular de pacientes. |
| MX2022003128A MX2022003128A (es) | 2015-09-10 | 2018-03-09 | Metodos de tratamiento de trastornos neurodegenerativos en una poblacion de pacientes particular. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022003128A MX2022003128A (es) | 2015-09-10 | 2018-03-09 | Metodos de tratamiento de trastornos neurodegenerativos en una poblacion de pacientes particular. |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US11191742B2 (es) |
| EP (2) | EP3347002B1 (es) |
| JP (4) | JP6789579B2 (es) |
| KR (2) | KR102547164B1 (es) |
| CN (3) | CN116712422A (es) |
| AU (1) | AU2016319107B2 (es) |
| CA (1) | CA2997376C (es) |
| DK (1) | DK3347002T3 (es) |
| ES (1) | ES2952727T3 (es) |
| FI (1) | FI3347002T3 (es) |
| HR (1) | HRP20230809T1 (es) |
| HU (1) | HUE062511T2 (es) |
| LT (1) | LT3347002T (es) |
| MD (1) | MD3347002T2 (es) |
| MX (2) | MX392677B (es) |
| PL (1) | PL3347002T3 (es) |
| PT (1) | PT3347002T (es) |
| RS (1) | RS64481B1 (es) |
| SI (1) | SI3347002T1 (es) |
| SM (1) | SMT202300250T1 (es) |
| WO (1) | WO2017044840A1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2941415A1 (en) | 2014-03-21 | 2015-09-24 | Alzheon, Inc. | Methods for treating neurological disorders |
| KR102547164B1 (ko) * | 2015-09-10 | 2023-06-22 | 알제온, 인크. | 특정 환자 집단에서 신경퇴행성 장애를 치료하는 방법 |
| CN108623501B (zh) | 2017-03-21 | 2022-04-19 | 润佳(苏州)医药科技有限公司 | 同位素富集的3-氨基-1-丙磺酸衍生物及其用途 |
| CN110003058B (zh) | 2018-01-04 | 2022-01-25 | 润佳(苏州)医药科技有限公司 | 3-((l-缬氨酰基)氨基)-3,3-二氘-1-丙磺酸晶型、制备方法及用途 |
| CN112867485A (zh) * | 2018-08-01 | 2021-05-28 | 阿尔泽恩股份有限公司 | 用于治疗神经变性病症的方法 |
| JP7466520B2 (ja) * | 2018-08-01 | 2024-04-12 | アルツェオン・インコーポレーテッド | 神経変性障害を治療するためのスルホプロパン酸誘導体 |
| CN111170901A (zh) * | 2018-11-13 | 2020-05-19 | 润佳(苏州)医药科技有限公司 | 3-((l-缬氨酰基)氨基)-1-丙磺酸晶型、制备方法及其用途 |
| WO2020257159A1 (en) | 2019-06-17 | 2020-12-24 | Alzheon, Inc. | Methods for treating neurodegenerative disorders |
| CN112791078B (zh) | 2019-11-13 | 2022-12-06 | 润佳(苏州)医药科技有限公司 | 同位素富集的3-氨基-1-丙磺酸及其衍生物的用途 |
| KR20240116529A (ko) * | 2021-12-09 | 2024-07-29 | 알제온, 인크. | 알츠하이머병 치료에 사용하기 위한 alz-801 |
| EP4475831A1 (en) * | 2022-02-07 | 2024-12-18 | Alzheon, Inc. | Alz-801 for use in treating a covid-19 associated neurological symptom |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5698155A (en) | 1991-05-31 | 1997-12-16 | Gs Technologies, Inc. | Method for the manufacture of pharmaceutical cellulose capsules |
| DE625212T1 (de) | 1992-10-13 | 2000-11-02 | Duke University, Durham | Verfahren zum entdecken von krankheit von alzheimer. |
| US20050031651A1 (en) | 2002-12-24 | 2005-02-10 | Francine Gervais | Therapeutic formulations for the treatment of beta-amyloid related diseases |
| US20070010573A1 (en) | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
| US20060079578A1 (en) | 2003-06-23 | 2006-04-13 | Julie Laurin | Pharmaceutical formulations of amyloid inhibiting compounds |
| US20050142191A1 (en) | 2003-06-23 | 2005-06-30 | Neurochem (International) Limited | Pharmaceutical formulations of amyloid inhibiting compounds |
| JP2007502418A (ja) | 2003-08-11 | 2007-02-08 | カリフォルニア・インスティテュート・オブ・テクノロジー | 微量流体大規模集積 |
| US20060257480A1 (en) * | 2005-04-12 | 2006-11-16 | Julie Laurin | Pharmaceutical formulations of amyloid inhibiting compounds |
| ES2967330T3 (es) | 2006-10-12 | 2024-04-29 | Bellus Health Inc | Métodos, compuestos, composiciones y vehículos para suministrar ácido 3-amino-1-propanosulfónico |
| MX2009005279A (es) | 2006-11-24 | 2009-05-28 | Ac Immune Sa | Derivados de n-(metil)-1h-pirazol-3-amina, n-(metil)-piridin-2-ami na y n-(metil)-tiazol-2-amina para el tratamiento de enfermedades asociadas con proteinas amiloides o tipo amiloide, tal como por ejemplo alzheimer. |
| JO3076B1 (ar) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
| EP2322163A1 (en) * | 2009-11-03 | 2011-05-18 | Pharnext | New therapeutics approaches for treating alzheimer disease |
| WO2012006329A2 (en) | 2010-07-06 | 2012-01-12 | Genomind, Llc | Apoe4 and apoj biomarker-based prevention and treatment of dementia |
| WO2012024616A1 (en) * | 2010-08-19 | 2012-02-23 | Buck Institute For Age Research | Methods of treating miild cognitive impairment (mci) and related discorders |
| US20150118231A1 (en) * | 2012-05-08 | 2015-04-30 | Ramot At Tel-Aviv University Ltd. | Apoe4 antibodies for treatment of neurodegenerative conditions |
| PT2994160T (pt) * | 2013-05-06 | 2019-08-07 | Baxalta Inc | Tratamento de sub-populações com doença de alzheimer com imunoglobulina g combinada |
| EP3718563A1 (en) * | 2014-02-08 | 2020-10-07 | F. Hoffmann-La Roche AG | Methods of treating alzheimer's disease |
| CA2941415A1 (en) | 2014-03-21 | 2015-09-24 | Alzheon, Inc. | Methods for treating neurological disorders |
| KR102547164B1 (ko) * | 2015-09-10 | 2023-06-22 | 알제온, 인크. | 특정 환자 집단에서 신경퇴행성 장애를 치료하는 방법 |
-
2016
- 2016-09-09 KR KR1020227009418A patent/KR102547164B1/ko active Active
- 2016-09-09 PT PT168451813T patent/PT3347002T/pt unknown
- 2016-09-09 MX MX2018003023A patent/MX392677B/es unknown
- 2016-09-09 KR KR1020187009381A patent/KR102412997B1/ko active Active
- 2016-09-09 AU AU2016319107A patent/AU2016319107B2/en active Active
- 2016-09-09 DK DK16845181.3T patent/DK3347002T3/da active
- 2016-09-09 RS RS20230603A patent/RS64481B1/sr unknown
- 2016-09-09 CA CA2997376A patent/CA2997376C/en active Active
- 2016-09-09 LT LTEPPCT/US2016/051091T patent/LT3347002T/lt unknown
- 2016-09-09 JP JP2018512564A patent/JP6789579B2/ja active Active
- 2016-09-09 MD MDE20180700T patent/MD3347002T2/ro unknown
- 2016-09-09 CN CN202310582365.9A patent/CN116712422A/zh active Pending
- 2016-09-09 EP EP16845181.3A patent/EP3347002B1/en active Active
- 2016-09-09 CN CN201680052760.4A patent/CN108289870A/zh active Pending
- 2016-09-09 WO PCT/US2016/051091 patent/WO2017044840A1/en not_active Ceased
- 2016-09-09 FI FIEP16845181.3T patent/FI3347002T3/fi active
- 2016-09-09 SI SI201631729T patent/SI3347002T1/sl unknown
- 2016-09-09 PL PL16845181.3T patent/PL3347002T3/pl unknown
- 2016-09-09 ES ES16845181T patent/ES2952727T3/es active Active
- 2016-09-09 US US15/758,405 patent/US11191742B2/en active Active
- 2016-09-09 HR HRP20230809TT patent/HRP20230809T1/hr unknown
- 2016-09-09 HU HUE16845181A patent/HUE062511T2/hu unknown
- 2016-09-09 EP EP23176559.5A patent/EP4275750A3/en active Pending
- 2016-09-09 SM SM20230250T patent/SMT202300250T1/it unknown
- 2016-09-09 CN CN202310582394.5A patent/CN116712423A/zh active Pending
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2018
- 2018-03-09 MX MX2022003128A patent/MX2022003128A/es unknown
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2020
- 2020-09-28 JP JP2020161995A patent/JP7128536B2/ja active Active
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2021
- 2021-09-17 US US17/477,886 patent/US20220096406A1/en not_active Abandoned
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2022
- 2022-08-12 JP JP2022128786A patent/JP2022145949A/ja active Pending
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2023
- 2023-09-06 US US18/462,238 patent/US20230414541A1/en active Pending
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2025
- 2025-02-17 JP JP2025023627A patent/JP2025065545A/ja active Pending
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