MX2017012942A - Formulaciones farmaceuticas. - Google Patents
Formulaciones farmaceuticas.Info
- Publication number
- MX2017012942A MX2017012942A MX2017012942A MX2017012942A MX2017012942A MX 2017012942 A MX2017012942 A MX 2017012942A MX 2017012942 A MX2017012942 A MX 2017012942A MX 2017012942 A MX2017012942 A MX 2017012942A MX 2017012942 A MX2017012942 A MX 2017012942A
- Authority
- MX
- Mexico
- Prior art keywords
- formulations
- pharmaceutical formulations
- thien
- methanesulfonyl
- oxo
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 3
- 239000013078 crystal Substances 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 108010005094 Advanced Glycation End Products Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 230000035699 permeability Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/541—Organic ions forming an ion pair complex with the pharmacologically or therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Esta invención se refiere a formulaciones farmacéuticas que comprenden 1-(2-tien-2'-il-2-oxo-etil)-3-(metansulfonil-hidrazina carbonil) piridinio, sus sales farmacéuticamente aceptables, sal-cocristales y cocristales, particularmente cloruro de 1-(2-tien-2'-il-2-oxo-etil)-3-(metansulfonil-hidrazina-carbonil) piridinio. Las formulaciones son adecuadas para la administración oral y también comprenden un potenciador de la permeabilidad o una base adecuada o una mezcla de los mismos. Las formulaciones de esta invención son para tratar enfermedades asociadas con productos finales de glicación avanzada.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1475MU2015 | 2015-04-08 | ||
| PCT/IB2016/051920 WO2016162787A1 (en) | 2015-04-08 | 2016-04-05 | Pharmaceutical formulations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2017012942A true MX2017012942A (es) | 2018-01-30 |
| MX387639B MX387639B (es) | 2025-03-18 |
Family
ID=55808800
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017012942A MX387639B (es) | 2015-04-08 | 2016-04-05 | Formulaciones farmacéuticas de compuesto de piridinio y un potenciador de la permeabilidad o una base. |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US10772879B2 (es) |
| EP (1) | EP3280447B1 (es) |
| JP (1) | JP6736656B2 (es) |
| KR (1) | KR20170134662A (es) |
| CN (1) | CN107530287B (es) |
| AR (1) | AR104185A1 (es) |
| AU (1) | AU2016246124B2 (es) |
| BR (1) | BR112017021669A2 (es) |
| CA (1) | CA2997463A1 (es) |
| CY (1) | CY1121921T1 (es) |
| DK (1) | DK3280447T3 (es) |
| EA (1) | EA037041B1 (es) |
| ES (1) | ES2724629T3 (es) |
| HR (1) | HRP20190783T1 (es) |
| HU (1) | HUE044889T2 (es) |
| IL (1) | IL254794B (es) |
| LT (1) | LT3280447T (es) |
| MX (1) | MX387639B (es) |
| MY (1) | MY182008A (es) |
| PH (1) | PH12017501829A1 (es) |
| PL (1) | PL3280447T3 (es) |
| PT (1) | PT3280447T (es) |
| RS (1) | RS58708B1 (es) |
| SG (1) | SG11201708142XA (es) |
| SI (1) | SI3280447T1 (es) |
| SM (1) | SMT201900264T1 (es) |
| TR (1) | TR201906476T4 (es) |
| TW (1) | TWI713512B (es) |
| UA (1) | UA123051C2 (es) |
| WO (1) | WO2016162787A1 (es) |
| ZA (1) | ZA201707094B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014007972A2 (en) | 2012-06-15 | 2014-01-09 | Nova Southeastern University | Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinphrine |
| ES2882530T3 (es) | 2013-03-22 | 2021-12-02 | Univ Nova Southeastern | Partículas finas de epinefrina y métodos para uso de las mismas para el tratamiento de condiciones que responden a la epinefrina |
| JP7657457B2 (ja) | 2018-10-19 | 2025-04-07 | ノバ サウスイースタン ユニバーシティー | pH修飾賦形剤及び浸入促進剤を含む舌下エピネフリン組成物及びそれを使用する方法 |
| US12178814B2 (en) | 2019-04-03 | 2024-12-31 | Astellas Pharma Inc. | Pharmaceutical composition |
| KR102330597B1 (ko) * | 2020-04-17 | 2021-11-26 | 보령제약 주식회사 | 무정형의 엠파글리플로진을 포함하는 안정성이 향상된 신규 약제학적 제형 |
| KR20220080880A (ko) * | 2020-12-08 | 2022-06-15 | 주식회사 종근당 | 엠파글리플로진 공결정을 함유하는 약제학적 조성물 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1154761B1 (en) * | 1999-02-22 | 2008-02-20 | Merrion Research I Limited | Solid oral dosage form containing an enhancer |
| AU769940B2 (en) * | 1999-10-06 | 2004-02-12 | Torrent Pharmaceuticals Ltd | Pyridinium derivatives for the management of aging-related and diabetic vascular complications, process for their preparation and therapeutic uses thereof |
| EP1243581B1 (en) | 2001-03-21 | 2005-07-13 | Torrent Pharmaceuticals Ltd | Pyridinium compounds useful for the treatment of AGE-related diseases |
| BRPI0708507A2 (pt) | 2006-03-03 | 2011-05-31 | Torrent Pharmaceuticals Ltd | Novos antagonistas de receptores de dupla ação (dara) para os receptores at1 eta |
| JP2009023932A (ja) * | 2007-07-18 | 2009-02-05 | Tama Tlo Kk | N−メチルピリジニウム化合物を有効成分として含有する抗ウイルス剤、それを含有する、抗ウイルス組成物、食餌及び動物用飼料 |
| US20110034378A1 (en) * | 2008-01-25 | 2011-02-10 | Chaitanya Dutt | Pharmaceutical Combinations Comprising Specified Age Breaker and Further Drugs, I.A. Antihypertensive Drugs, Antidiabetic Drugs Etc. |
| CN101574343B (zh) * | 2008-05-07 | 2011-06-01 | 吉林大学 | 一种治疗糖尿病的药物组合物 |
| WO2010128528A2 (en) * | 2009-05-07 | 2010-11-11 | Torrent Pharmaceuticals Limited | Novel heterocyclic compounds |
| WO2011084618A2 (en) * | 2009-12-16 | 2011-07-14 | Nod Pharmaceuticals, Inc. | Compositions and methods for oral drug delivery |
| CN104069066B (zh) * | 2013-03-25 | 2017-04-19 | 吉林大学 | 黄癸固体分散体及其在治疗糖尿病及并发症中的应用 |
-
2016
- 2016-04-05 SM SM20190264T patent/SMT201900264T1/it unknown
- 2016-04-05 DK DK16718474.6T patent/DK3280447T3/da active
- 2016-04-05 TR TR2019/06476T patent/TR201906476T4/tr unknown
- 2016-04-05 MY MYPI2017001475A patent/MY182008A/en unknown
- 2016-04-05 HU HUE16718474 patent/HUE044889T2/hu unknown
- 2016-04-05 BR BR112017021669A patent/BR112017021669A2/pt not_active Application Discontinuation
- 2016-04-05 US US15/564,720 patent/US10772879B2/en not_active Expired - Fee Related
- 2016-04-05 PL PL16718474T patent/PL3280447T3/pl unknown
- 2016-04-05 HR HRP20190783TT patent/HRP20190783T1/hr unknown
- 2016-04-05 AR ARP160100918A patent/AR104185A1/es unknown
- 2016-04-05 PT PT16718474T patent/PT3280447T/pt unknown
- 2016-04-05 UA UAA201710864A patent/UA123051C2/uk unknown
- 2016-04-05 MX MX2017012942A patent/MX387639B/es unknown
- 2016-04-05 WO PCT/IB2016/051920 patent/WO2016162787A1/en not_active Ceased
- 2016-04-05 EA EA201792237A patent/EA037041B1/ru unknown
- 2016-04-05 AU AU2016246124A patent/AU2016246124B2/en not_active Ceased
- 2016-04-05 RS RS20190537A patent/RS58708B1/sr unknown
- 2016-04-05 ES ES16718474T patent/ES2724629T3/es active Active
- 2016-04-05 CN CN201680020704.2A patent/CN107530287B/zh not_active Expired - Fee Related
- 2016-04-05 SG SG11201708142XA patent/SG11201708142XA/en unknown
- 2016-04-05 SI SI201630246T patent/SI3280447T1/sl unknown
- 2016-04-05 LT LTEP16718474.6T patent/LT3280447T/lt unknown
- 2016-04-05 CA CA2997463A patent/CA2997463A1/en not_active Abandoned
- 2016-04-05 EP EP16718474.6A patent/EP3280447B1/en active Active
- 2016-04-05 KR KR1020177032035A patent/KR20170134662A/ko not_active Withdrawn
- 2016-04-05 JP JP2018503835A patent/JP6736656B2/ja not_active Expired - Fee Related
- 2016-04-06 TW TW105110715A patent/TWI713512B/zh not_active IP Right Cessation
-
2017
- 2017-09-28 IL IL254794A patent/IL254794B/en active IP Right Grant
- 2017-10-06 PH PH12017501829A patent/PH12017501829A1/en unknown
- 2017-10-19 ZA ZA2017/07094A patent/ZA201707094B/en unknown
-
2019
- 2019-05-03 CY CY20191100471T patent/CY1121921T1/el unknown
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