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MX2016011837A - Composiciones de inhibidores de la dopa decarboxilasa. - Google Patents

Composiciones de inhibidores de la dopa decarboxilasa.

Info

Publication number
MX2016011837A
MX2016011837A MX2016011837A MX2016011837A MX2016011837A MX 2016011837 A MX2016011837 A MX 2016011837A MX 2016011837 A MX2016011837 A MX 2016011837A MX 2016011837 A MX2016011837 A MX 2016011837A MX 2016011837 A MX2016011837 A MX 2016011837A
Authority
MX
Mexico
Prior art keywords
die
disease
carbidopa
antioxidant
compositions
Prior art date
Application number
MX2016011837A
Other languages
English (en)
Inventor
Oron Yacoby-Zeevi
Original Assignee
Neuroderm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53488380&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2016011837(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neuroderm Ltd filed Critical Neuroderm Ltd
Publication of MX2016011837A publication Critical patent/MX2016011837A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/133—Amines having hydroxy groups, e.g. sphingosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención proporciona composiciones farmacéuticas a base de carbidopa altamente estables que comprenden una combinación de antioxidantes que consisten en ácido ascórbico y al menos un antioxidante adicional, en donde dicha combinación inhibe fuertemente la degradación de carbidopa; estas composiciones pueden comprender además levodopa y/o una o ambas de arginina y meglumina, y son benéficas en el tratamiento de una enfermedad, trastorno o condición asociada con la pérdida de dopamina o neuronas dopaminérgicas, por ejemplo, enfermedad de Parkinson.
MX2016011837A 2014-03-13 2015-03-12 Composiciones de inhibidores de la dopa decarboxilasa. MX2016011837A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461952477P 2014-03-13 2014-03-13
US201461990967P 2014-05-09 2014-05-09
PCT/IL2015/050258 WO2015136538A1 (en) 2014-03-13 2015-03-12 Dopa decarboxylase inhibitor compositions

Publications (1)

Publication Number Publication Date
MX2016011837A true MX2016011837A (es) 2017-04-27

Family

ID=53488380

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016011837A MX2016011837A (es) 2014-03-13 2015-03-12 Composiciones de inhibidores de la dopa decarboxilasa.

Country Status (19)

Country Link
US (4) US10022320B2 (es)
EP (3) EP3777833B1 (es)
JP (2) JP6591995B2 (es)
CN (1) CN106413754B (es)
AU (1) AU2015228369B2 (es)
BR (1) BR112016021034A8 (es)
CA (1) CA2942244C (es)
DK (2) DK3116475T3 (es)
ES (2) ES2836325T3 (es)
FI (1) FI3777833T3 (es)
HR (2) HRP20201948T1 (es)
HU (2) HUE052642T2 (es)
IL (1) IL247668B (es)
MX (1) MX2016011837A (es)
PL (2) PL3777833T3 (es)
PT (2) PT3777833T (es)
RS (1) RS65060B1 (es)
RU (1) RU2684105C2 (es)
WO (1) WO2015136538A1 (es)

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Also Published As

Publication number Publication date
DK3116475T3 (da) 2020-12-07
US20210038505A1 (en) 2021-02-11
EP4299128A3 (en) 2024-04-17
US20190151233A1 (en) 2019-05-23
IL247668B (en) 2020-09-30
CA2942244A1 (en) 2015-09-17
HRP20231716T1 (hr) 2024-03-15
US20150352212A1 (en) 2015-12-10
ES2967693T3 (es) 2024-05-03
FI3777833T3 (fi) 2024-01-03
WO2015136538A1 (en) 2015-09-17
PT3777833T (pt) 2024-01-09
AU2015228369B2 (en) 2020-05-21
JP6591995B2 (ja) 2019-10-16
HUE052642T2 (hu) 2021-05-28
RU2016135952A (ru) 2018-04-13
CN106413754A (zh) 2017-02-15
HUE064818T2 (hu) 2024-04-28
RU2684105C2 (ru) 2019-04-04
RU2016135952A3 (es) 2018-09-12
EP3777833B1 (en) 2023-10-18
CN106413754B (zh) 2019-11-29
CA2942244C (en) 2022-08-23
EP3116475B1 (en) 2020-11-04
RS65060B1 (sr) 2024-02-29
US10022320B2 (en) 2018-07-17
EP3116475A1 (en) 2017-01-18
BR112016021034A2 (pt) 2017-08-15
US20230240980A1 (en) 2023-08-03
PL3116475T3 (pl) 2021-02-08
BR112016021034A8 (pt) 2021-06-29
EP3777833A1 (en) 2021-02-17
DK3777833T3 (da) 2023-12-18
ES2836325T3 (es) 2021-06-24
JP6770158B2 (ja) 2020-10-14
US10624839B2 (en) 2020-04-21
JP2020011977A (ja) 2020-01-23
PT3116475T (pt) 2020-12-15
JP2017507973A (ja) 2017-03-23
EP4299128A2 (en) 2024-01-03
PL3777833T3 (pl) 2024-03-25
IL247668A0 (en) 2016-11-30
HRP20201948T1 (hr) 2021-01-22
AU2015228369A1 (en) 2016-10-27

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