MX2012013395A - Matriz sintetica absorbible reforzada para aplicaciones hemostaticas. - Google Patents
Matriz sintetica absorbible reforzada para aplicaciones hemostaticas.Info
- Publication number
- MX2012013395A MX2012013395A MX2012013395A MX2012013395A MX2012013395A MX 2012013395 A MX2012013395 A MX 2012013395A MX 2012013395 A MX2012013395 A MX 2012013395A MX 2012013395 A MX2012013395 A MX 2012013395A MX 2012013395 A MX2012013395 A MX 2012013395A
- Authority
- MX
- Mexico
- Prior art keywords
- reinforced absorbable
- synthetic matrix
- absorbable synthetic
- hemostatic applications
- hemostatic
- Prior art date
Links
- 230000002439 hemostatic effect Effects 0.000 title 1
- 239000011159 matrix material Substances 0.000 title 1
- 239000002874 hemostatic agent Substances 0.000 abstract 2
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Polymers OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 abstract 1
- 229920000954 Polyglycolide Polymers 0.000 abstract 1
- 229940030225 antihemorrhagics Drugs 0.000 abstract 1
- 239000000835 fiber Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920000747 poly(lactic acid) Polymers 0.000 abstract 1
- 229920002463 poly(p-dioxanone) polymer Polymers 0.000 abstract 1
- 239000000622 polydioxanone Substances 0.000 abstract 1
- 239000002356 single layer Substances 0.000 abstract 1
- 229920002994 synthetic fiber Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/363—Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4833—Thrombin (3.4.21.5)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
- A61L2300/254—Enzymes, proenzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/04—Materials for stopping bleeding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se dirige a un hemostático absorbible reforzado que comprende al menos un agente hemostático en una sola capa de una tela sintética no tejida que tiene una mezcla de segmentos de fibras comprimidas de un copolímero de poliglicólido/poliláctido y una polidioxanona.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/781,103 US8273369B2 (en) | 2010-05-17 | 2010-05-17 | Reinforced absorbable synthetic matrix for hemostatic applications |
| PCT/US2011/036590 WO2011146359A1 (en) | 2010-05-17 | 2011-05-16 | Reinforced absorbable synthetic matrix for hemostatic applications |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2012013395A true MX2012013395A (es) | 2012-12-10 |
Family
ID=44911985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012013395A MX2012013395A (es) | 2010-05-17 | 2011-05-16 | Matriz sintetica absorbible reforzada para aplicaciones hemostaticas. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US8273369B2 (es) |
| EP (1) | EP2571540B1 (es) |
| JP (1) | JP5905451B2 (es) |
| CN (2) | CN106215217A (es) |
| AU (1) | AU2011256403B2 (es) |
| BR (1) | BR112012029293B1 (es) |
| CA (1) | CA2799916C (es) |
| ES (1) | ES2659173T3 (es) |
| MX (1) | MX2012013395A (es) |
| RU (1) | RU2574016C2 (es) |
| WO (1) | WO2011146359A1 (es) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG186379A1 (en) | 2010-06-17 | 2013-01-30 | Univ Washington | Biomedical patches with aligned fibers |
| MX357254B (es) * | 2012-05-14 | 2018-07-03 | Teijin Pharma Ltd | Producto moldeado en hoja y material hemostatico. |
| KR102037555B1 (ko) * | 2012-05-14 | 2019-10-28 | 데이진 가부시키가이샤 | 멸균 조성물 |
| US9259435B2 (en) | 2012-08-31 | 2016-02-16 | W. L. Gore & Associates, Inc. | Reactive oxidative species generating materials and methods of use |
| US20140065090A1 (en) * | 2012-08-31 | 2014-03-06 | W. L. Gore & Associates, Inc. | Reactive Oxidative Species Generating Materials and Methods of Use |
| AU2015268656B2 (en) * | 2012-08-31 | 2016-11-03 | W. L. Gore & Associates, Inc. | Reactive oxidative species generating materials and methods of use |
| WO2014046669A1 (en) | 2012-09-21 | 2014-03-27 | Washington University | Biomedical patches with spatially arranged fibers |
| KR101878774B1 (ko) * | 2015-04-15 | 2018-07-17 | 주식회사 삼양바이오팜 | 다기능성 지혈제 및 그 제조 방법 |
| US10349938B2 (en) | 2015-08-31 | 2019-07-16 | Ethicon Llc | Surgical adjuncts with medicants affected by activator materials |
| US9937283B2 (en) | 2015-08-31 | 2018-04-10 | Ethicon Endo-Surgery, Llc | Adjunct material to provide drug elution from vessels |
| US10279086B2 (en) | 2015-08-31 | 2019-05-07 | Ethicon Llc | Composite adjunct materials for delivering medicants |
| US10188390B2 (en) | 2015-08-31 | 2019-01-29 | Ethicon Llc | Adjunct material to provide heterogeneous drug elution |
| US10569071B2 (en) | 2015-08-31 | 2020-02-25 | Ethicon Llc | Medicant eluting adjuncts and methods of using medicant eluting adjuncts |
| US10130738B2 (en) | 2015-08-31 | 2018-11-20 | Ethicon Llc | Adjunct material to promote tissue growth |
| US10172973B2 (en) | 2015-08-31 | 2019-01-08 | Ethicon Llc | Surgical adjuncts and medicants for promoting lung function |
| US10245034B2 (en) | 2015-08-31 | 2019-04-02 | Ethicon Llc | Inducing tissue adhesions using surgical adjuncts and medicants |
| US10213520B2 (en) | 2015-08-31 | 2019-02-26 | Ethicon Llc | Surgical adjuncts having medicants controllably releasable therefrom |
| US10076329B2 (en) | 2015-08-31 | 2018-09-18 | Ethicon Llc | Adjunct material to promote tissue growth in a colon |
| US10111661B2 (en) | 2015-08-31 | 2018-10-30 | Ethicon Llc | Matrix metalloproteinase inhibiting adjuncts for surgical devices |
| US10194936B2 (en) | 2015-08-31 | 2019-02-05 | Ethicon Endo-Surgery, Llc | Adjunct material for delivery to stomach tissue |
| US10285692B2 (en) | 2015-08-31 | 2019-05-14 | Ethicon Llc | Adjuncts for surgical devices including agonists and antagonists |
| US10076324B2 (en) | 2015-08-31 | 2018-09-18 | Ethicon Llc | Adjunct material to provide controlled drug elution |
| US10086116B2 (en) | 2015-08-31 | 2018-10-02 | Ethicon Llc | Adjunct material to provide controlled drug release |
| US10463366B2 (en) | 2015-08-31 | 2019-11-05 | Ethicon Llc | Adjunct materials for delivery to liver tissue |
| US11020116B2 (en) | 2015-08-31 | 2021-06-01 | Ethicon Llc | Surgical adjuncts with medicants affected by activators |
| US10188389B2 (en) | 2015-08-31 | 2019-01-29 | Ethicon Llc | Adjunct material for delivery to colon tissue |
| US10499913B2 (en) | 2015-08-31 | 2019-12-10 | Ethicon Llc | Tubular surgical constructs including adjunct material |
| BR112018008895B1 (pt) | 2015-11-06 | 2021-11-16 | Ethicon, Inc. | Agregados hemostáticos e método para sua produção |
| EP3426207A1 (fr) * | 2016-03-08 | 2019-01-16 | Urgo Recherche Innovation et Développement | Pansement se présentant sous la forme d'une bande autoadhérente |
| US10632228B2 (en) | 2016-05-12 | 2020-04-28 | Acera Surgical, Inc. | Tissue substitute materials and methods for tissue repair |
| EP4473984A3 (en) * | 2016-05-12 | 2025-02-19 | Acera Surgical, Inc. | Tissue substitute materials and methods for tissue repair |
| US11413335B2 (en) | 2018-02-13 | 2022-08-16 | Guangzhou Bioseal Biotech Co. Ltd | Hemostatic compositions and methods of making thereof |
| CN107754005B (zh) * | 2016-08-15 | 2021-06-15 | 广州倍绣生物技术有限公司 | 止血组合物及其制造方法 |
| US11254061B2 (en) | 2017-01-06 | 2022-02-22 | Ethicon, Inc. | Scaffolds for implanting absorbable hemostats in field conditions |
| US11007299B2 (en) * | 2017-11-08 | 2021-05-18 | Ethicon, Inc. | Hemostatic paste having surface enriched with hemostasis-promoting agents and devices for delivery |
| KR20210143764A (ko) | 2019-03-20 | 2021-11-29 | 아스텔라스세이야쿠 가부시키가이샤 | 트롬빈 담지 지혈용 시트 |
| JP7589416B2 (ja) | 2019-07-12 | 2024-11-26 | ガット テクノロジーズ ビー.ブイ. | 生体適合性の可撓性止血シート |
| KR102839583B1 (ko) * | 2019-07-12 | 2025-07-30 | 가트 테크놀로지스 비.브이. | 생체적합성의 유연성 지혈 시트 |
| EP3996760B1 (en) | 2019-07-12 | 2023-08-09 | Cilag GmbH International | Method for preparing a tissue-adhesive sheet |
| US12102722B2 (en) | 2020-06-08 | 2024-10-01 | Ethicon, Inc. | Napped coated wound dressing |
| US11826028B2 (en) * | 2020-06-10 | 2023-11-28 | Ethicon, Inc. | Two component sealing systems including synthetic matrices and biosynthetic adhesives for sealing resected surfaces of organs to control bleeding, fluid leaks and air leaks |
| CA3227438A1 (en) | 2021-07-29 | 2023-02-02 | Acera Surgical, Inc. | Combined macro and micro-porous hybrid-scale fiber matrix |
| EP4377502A4 (en) | 2021-07-29 | 2025-05-28 | Acera Surgical, Inc. | Particle-form hybrid-scale fiber matrix |
| US12167853B2 (en) | 2021-09-07 | 2024-12-17 | Acera Surgical, Inc. | Non-woven graft materials for nerve repair and regeneration |
| CN117982740B (zh) * | 2024-04-07 | 2024-07-12 | 四川国纳科技有限公司 | 可吸收生物医用高分子材料、结扎夹及制备方法 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3364200A (en) | 1960-03-28 | 1968-01-16 | Johnson & Johnson | Oxidized cellulose product and method for preparing the same |
| US4440789A (en) * | 1982-11-16 | 1984-04-03 | Ethicon, Inc. | Synthetic absorbable hemostatic composition |
| US4626253A (en) | 1984-10-05 | 1986-12-02 | Johnson & Johnson Products, Inc. | Surgical hemostat comprising oxidized cellulose |
| US4741337A (en) * | 1985-07-17 | 1988-05-03 | Ethicon, Inc. | Surgical fastener made from glycolide-rich polymer blends |
| CN1035803C (zh) * | 1990-07-24 | 1997-09-10 | 中国化工进出口总公司 | 可溶性止血织物 |
| US5180398A (en) | 1990-12-20 | 1993-01-19 | Johnson & Johnson Medical, Inc. | Cellulose oxidation by a perfluorinated hydrocarbon solution of nitrogen dioxide |
| WO1993017635A1 (en) | 1992-03-04 | 1993-09-16 | C.R. Bard, Inc. | Composite prosthesis and method for limiting the incidence of postoperative adhesions |
| CA2114282A1 (en) | 1993-01-28 | 1994-07-29 | Lothar Schilder | Multi-layered implant |
| US5393594A (en) | 1993-10-06 | 1995-02-28 | United States Surgical Corporation | Absorbable non-woven fabric |
| US6762336B1 (en) | 1998-01-19 | 2004-07-13 | The American National Red Cross | Hemostatic sandwich bandage |
| US6733774B2 (en) * | 2001-01-25 | 2004-05-11 | Nycomed Pharma As | Carrier with solid fibrinogen and solid thrombin |
| US7824701B2 (en) | 2002-10-18 | 2010-11-02 | Ethicon, Inc. | Biocompatible scaffold for ligament or tendon repair |
| EP1588722A4 (en) * | 2003-01-20 | 2011-03-02 | Chemo Sero Therapeut Res Inst | HEMOSTATIC MATERIALS |
| RU2005134239A (ru) * | 2003-04-04 | 2006-05-10 | Тиссьюмед Лимитед (Gb) | Составы тканевых клеев |
| US9358318B2 (en) | 2004-10-20 | 2016-06-07 | Ethicon, Inc. | Method of making a reinforced absorbable multilayered hemostatic wound dressing |
| KR20070095870A (ko) * | 2004-10-20 | 2007-10-01 | 에디컨인코포레이티드 | 흡수성 지혈제 |
| CN101084021B (zh) * | 2004-10-20 | 2011-05-04 | 伊西康公司 | 加固的可吸收多层止血伤口敷料及其制造方法和用途 |
| PL2345430T3 (pl) * | 2004-10-20 | 2016-05-31 | Ethicon Inc | Wzmocniony, absorbowalny, wielowarstwowy materiał do zastosowania w wyrobach medycznych oraz sposób jego wytwarzania |
| EP2018449A1 (en) * | 2006-04-10 | 2009-01-28 | Ethicon, Inc | A reinforced absorbable multilayered fabric for use in medical devices and method of manufacture |
| BRPI0621537B8 (pt) * | 2006-04-10 | 2021-05-25 | Ethicon Inc | curativo hemostático de múltiplas camadas absorvível e reforçado para curativo, e método de fabricação |
| JP5547480B2 (ja) | 2006-08-04 | 2014-07-16 | エスティービー リミテッド | 創傷組織を治療するための固体包帯材の製造方法 |
| US20080095830A1 (en) * | 2006-10-20 | 2008-04-24 | Van Holten Robert W | Method for making a dressing |
| US20090004253A1 (en) * | 2007-06-29 | 2009-01-01 | Brown Laura J | Composite device for the repair or regeneration of tissue |
| JP2010069031A (ja) * | 2008-09-19 | 2010-04-02 | Chemo Sero Therapeut Res Inst | シート状フィブリン糊接着剤 |
| US8758447B2 (en) * | 2009-06-30 | 2014-06-24 | Ethicon, Inc. | Device and method for repair of urological structures |
-
2010
- 2010-05-17 US US12/781,103 patent/US8273369B2/en active Active
-
2011
- 2011-05-16 CN CN201610772099.6A patent/CN106215217A/zh active Pending
- 2011-05-16 WO PCT/US2011/036590 patent/WO2011146359A1/en not_active Ceased
- 2011-05-16 CA CA2799916A patent/CA2799916C/en active Active
- 2011-05-16 BR BR112012029293-5A patent/BR112012029293B1/pt not_active IP Right Cessation
- 2011-05-16 JP JP2013511251A patent/JP5905451B2/ja not_active Expired - Fee Related
- 2011-05-16 RU RU2012154328/15A patent/RU2574016C2/ru active
- 2011-05-16 AU AU2011256403A patent/AU2011256403B2/en not_active Ceased
- 2011-05-16 MX MX2012013395A patent/MX2012013395A/es active IP Right Grant
- 2011-05-16 CN CN2011800244212A patent/CN102892439A/zh active Pending
- 2011-05-16 ES ES11784012.4T patent/ES2659173T3/es active Active
- 2011-05-16 EP EP11784012.4A patent/EP2571540B1/en not_active Not-in-force
-
2012
- 2012-08-22 US US13/591,501 patent/US8383147B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| BR112012029293B1 (pt) | 2019-04-24 |
| AU2011256403B2 (en) | 2013-10-03 |
| AU2011256403A1 (en) | 2012-12-06 |
| US20120315316A1 (en) | 2012-12-13 |
| CN102892439A (zh) | 2013-01-23 |
| US8383147B2 (en) | 2013-02-26 |
| JP2013526368A (ja) | 2013-06-24 |
| EP2571540A1 (en) | 2013-03-27 |
| EP2571540B1 (en) | 2018-01-17 |
| CA2799916C (en) | 2018-03-13 |
| BR112012029293A2 (pt) | 2015-09-22 |
| CA2799916A1 (en) | 2011-11-24 |
| RU2574016C2 (ru) | 2016-01-27 |
| ES2659173T3 (es) | 2018-03-14 |
| US20110280919A1 (en) | 2011-11-17 |
| WO2011146359A1 (en) | 2011-11-24 |
| US8273369B2 (en) | 2012-09-25 |
| JP5905451B2 (ja) | 2016-04-20 |
| EP2571540A4 (en) | 2013-11-20 |
| CN106215217A (zh) | 2016-12-14 |
| RU2012154328A (ru) | 2014-06-27 |
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