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MX2010005682A - Anticuerpos bivalentes, biespecificos. - Google Patents

Anticuerpos bivalentes, biespecificos.

Info

Publication number
MX2010005682A
MX2010005682A MX2010005682A MX2010005682A MX2010005682A MX 2010005682 A MX2010005682 A MX 2010005682A MX 2010005682 A MX2010005682 A MX 2010005682A MX 2010005682 A MX2010005682 A MX 2010005682A MX 2010005682 A MX2010005682 A MX 2010005682A
Authority
MX
Mexico
Prior art keywords
bivalent
bispecific antibodies
manufacture
relates
present
Prior art date
Application number
MX2010005682A
Other languages
English (en)
Inventor
Wolfgang Schaefer
Christian Klein
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2010005682A publication Critical patent/MX2010005682A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/468Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/522CH1 domain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/526CH3 domain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención está relacionada con nuevos anticuerpos bivalentes biespecíficos con intercambio de dominios, su elaboración y su utilización.
MX2010005682A 2007-12-21 2008-12-16 Anticuerpos bivalentes, biespecificos. MX2010005682A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07024866 2007-12-21
PCT/EP2008/010705 WO2009080254A1 (en) 2007-12-21 2008-12-16 Bivalent, bispecific antibodies

Publications (1)

Publication Number Publication Date
MX2010005682A true MX2010005682A (es) 2010-06-22

Family

ID=39684152

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010005682A MX2010005682A (es) 2007-12-21 2008-12-16 Anticuerpos bivalentes, biespecificos.

Country Status (15)

Country Link
US (1) US8227577B2 (es)
EP (1) EP2238173A1 (es)
JP (1) JP2011507489A (es)
KR (1) KR101266659B1 (es)
CN (1) CN101903405A (es)
AR (1) AR069797A1 (es)
AU (1) AU2008340695A1 (es)
BR (1) BRPI0821405A2 (es)
CA (1) CA2709347A1 (es)
CL (1) CL2008003782A1 (es)
IL (1) IL205750A0 (es)
MX (1) MX2010005682A (es)
PE (1) PE20091520A1 (es)
TW (1) TW200932270A (es)
WO (1) WO2009080254A1 (es)

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WO2009080254A1 (en) 2009-07-02
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CN101903405A (zh) 2010-12-01
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AR069797A1 (es) 2010-02-17
CL2008003782A1 (es) 2010-02-12

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