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MX2009012924A - Toxina clostridial netb. - Google Patents

Toxina clostridial netb.

Info

Publication number
MX2009012924A
MX2009012924A MX2009012924A MX2009012924A MX2009012924A MX 2009012924 A MX2009012924 A MX 2009012924A MX 2009012924 A MX2009012924 A MX 2009012924A MX 2009012924 A MX2009012924 A MX 2009012924A MX 2009012924 A MX2009012924 A MX 2009012924A
Authority
MX
Mexico
Prior art keywords
toxin
clostridial toxin
methods
netb
relates
Prior art date
Application number
MX2009012924A
Other languages
English (en)
Inventor
Robert John Moore
Julian Ian Rood
Anthony Leslie Keyburn
Original Assignee
Australian Poultry Crc Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40093085&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009012924(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Australian Poultry Crc Pty Ltd filed Critical Australian Poultry Crc Pty Ltd
Publication of MX2009012924A publication Critical patent/MX2009012924A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36Adaptation or attenuation of cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/517Plant cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La presente invención se refiere a una toxina basada en polipéptido que se origina a partir de Clostridium perfringens. La invención también se refiere a composiciones inmunogénicas que comprenden la toxina y a métodos para vacunar animales, por ejemplo pollos, de modo tal que éstos sean menos susceptibles a enfermedades clostridiales. También se describen métodos para determinar si un animal ha estado expuesto o no a la toxina, polinucleótido que codifica para la toxina y bacteria atenuada que exprese una forma reducida o menos activa de la toxina.
MX2009012924A 2007-06-08 2008-06-06 Toxina clostridial netb. MX2009012924A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94285807P 2007-06-08 2007-06-08
PCT/AU2008/000813 WO2008148166A1 (en) 2007-06-08 2008-06-06 Clostridial toxin netb

Publications (1)

Publication Number Publication Date
MX2009012924A true MX2009012924A (es) 2010-03-25

Family

ID=40093085

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009012924A MX2009012924A (es) 2007-06-08 2008-06-06 Toxina clostridial netb.

Country Status (14)

Country Link
US (1) US8263088B2 (es)
EP (2) EP2980100A1 (es)
JP (2) JP5901115B2 (es)
CN (1) CN101903399B (es)
AU (1) AU2008258277B2 (es)
BR (1) BRPI0812346B1 (es)
CA (1) CA2689302C (es)
ES (1) ES2550685T3 (es)
HU (1) HUE025717T2 (es)
MX (1) MX2009012924A (es)
PL (1) PL2164862T3 (es)
PT (1) PT2164862E (es)
RU (1) RU2474587C2 (es)
WO (1) WO2008148166A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2391640B1 (en) * 2009-01-30 2014-05-14 Intervet International B.V. A clostridium chauvoei polypeptide, dna encoding the polypeptide and a vaccine comprising the polypeptide
WO2011113801A1 (en) * 2010-03-16 2011-09-22 Universiteit Gent Use of clostridium perfringens strain 23 to protect against necrotic enteritis
GB201118394D0 (en) 2011-10-25 2011-12-07 Univ Exeter Vaccine
US10174086B2 (en) 2011-10-25 2019-01-08 University Of Exeter Vaccine
KR101293667B1 (ko) 2011-11-16 2013-08-07 대한민국 닭의 괴사성 장염을 예방하는 백신 조성물
ES2637401T3 (es) 2012-03-29 2017-10-13 University Of Exeter Epítopos de toxina épsilon de Clostridium perfringens con toxicidad reducida
US9493519B2 (en) * 2012-05-23 2016-11-15 University Of Guelph Toxin in type A Clostridium perfringens
GB201322463D0 (en) * 2013-12-18 2014-02-05 Univ Exeter Composition
US9505810B2 (en) 2014-08-22 2016-11-29 University Of Guelph Toxins in type A Clostridium perfringens
EP3112474A1 (en) 2015-06-29 2017-01-04 Evonik Degussa GmbH Method of detecting avian necrotic enteritis
HUE062498T2 (hu) * 2017-05-12 2023-11-28 Evonik Operations Gmbh Eljárás madárállományban C. perfringens által kiváltott betegségek kimutatására
WO2018206690A1 (en) * 2017-05-12 2018-11-15 Evonik Degussa Gmbh Method for detecting c. perfringens induced diseases in animals
JP2020527051A (ja) * 2017-05-31 2020-09-03 ハー マジェスティー ザ クイーン イン ライト オブ カナダ アズ リプレゼンティッド バイ ザ ミニスター オブ アグリカルチャー アンド アグリ−フードHer Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri−Food 家禽における壊疽性腸炎に対するワクチン
MX2020009044A (es) 2018-03-02 2020-10-12 Evonik Operations Gmbh Procedimiento in vitro para detectar disfuncion de la barrera intestinal en animales.
KR20210014136A (ko) * 2018-05-29 2021-02-08 에보니크 오퍼레이션즈 게엠베하 동물 집단에서의 병원체 부하를 모니터링하기 위한 시험관내 방법
US20210262031A1 (en) * 2018-06-15 2021-08-26 Evonik Operations Gmbh Method for early detection of a necrotic enteritis outbreak in an avian population
CA3103656A1 (en) * 2018-07-05 2020-02-20 Novobind Livestock Therapeutics Inc. Antibodies against disease causing agents of poultry and uses thereof
US12449424B2 (en) 2018-12-14 2025-10-21 Evonik Operations Gmbh In vitro method for detecting avian intestinal dysbiosis
KR102207354B1 (ko) * 2019-09-02 2021-01-27 (주)제이비바이오텍 CRISPR/Cas9 기반 Bacillus subtilis 유전체 편집 메커니즘을 이용한 닭의 괴사성장염 백신
US11381146B2 (en) 2019-09-04 2022-07-05 Nti Ag Drive device having a tubular linear motor and a stainless steel casing
CN113717292B (zh) * 2021-09-27 2023-04-21 华中农业大学 一种针对鸡坏死性肠炎的融合蛋白疫苗及其制备方法
CN116284281B (zh) * 2023-03-07 2025-10-03 广东省农业科学院动物卫生研究所 G型产气荚膜梭菌的重组蛋白、疫苗及应用

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2413974A1 (fr) 1978-01-06 1979-08-03 David Bernard Sechoir pour feuilles imprimees par serigraphie
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
EP0265502A1 (en) 1986-04-30 1988-05-04 Boyce Thompson Institute For Plant Research, Inc. Electric field mediated dna transformation of plant cells and organelles
US5177010A (en) 1986-06-30 1993-01-05 University Of Toledo Process for transforming corn and the products thereof
US4903635A (en) 1986-07-02 1990-02-27 Embrex, Inc. High speed automated injection system for avian embryos
SE455438B (sv) 1986-11-24 1988-07-11 Aga Ab Sett att senka en brennares flamtemperatur samt brennare med munstycken for oxygen resp brensle
US5004863B2 (en) 1986-12-03 2000-10-17 Agracetus Genetic engineering of cotton plants and lines
DE69029036T2 (de) 1989-06-29 1997-05-22 Medarex Inc Bispezifische reagenzien für die aids-therapie
US5141131A (en) 1989-06-30 1992-08-25 Dowelanco Method and apparatus for the acceleration of a propellable matter
US5056464A (en) 1990-01-18 1991-10-15 Embrex, Inc. Automated injection system for avian embryos with advanced fluid delivery system
DE69133512T2 (de) 1990-11-23 2006-09-28 Bayer Bioscience N.V. Verfahren zur Transformation monokotyler Pflanzen
US5384253A (en) 1990-12-28 1995-01-24 Dekalb Genetics Corporation Genetic transformation of maize cells by electroporation of cells pretreated with pectin degrading enzymes
JPH06507398A (ja) 1991-05-14 1994-08-25 リプリジェン コーポレーション Hiv感染治療のための異種複合抗体
US5136979A (en) 1991-09-25 1992-08-11 Embrex, Inc. Modular injection system for avian embryos
WO1993008829A1 (en) 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
US5643578A (en) 1992-03-23 1997-07-01 University Of Massachusetts Medical Center Immunization by inoculation of DNA transcription unit
WO1993021335A2 (en) 1992-04-15 1993-10-28 Plant Genetic Systems, N.V. Transformation of monocot cells
DE69426051T2 (de) 1993-07-30 2001-05-10 Akzo Nobel N.V., Arnheim/Arnhem Impfstoff für Geflügel
EP0740704A1 (en) 1994-01-27 1996-11-06 University Of Massachusetts Medical Center Immunization by inoculation of dna transcription unit
PT750907E (pt) * 1995-06-30 2002-08-30 American Cyanamid Co Formulacoes de vacinas estaveis para administracao parenterica metodo para a sua utilizacao e processo para a sua preparacao
US5792294A (en) 1995-11-16 1998-08-11 Otis Elevator Company Method of replacing sheave liner
US5939400A (en) 1996-02-26 1999-08-17 The Board Of Trustees Of The Leland Stanford Junior University DNA vaccination for induction of suppressive T cell response
GB9605222D0 (en) * 1996-03-12 1996-05-15 Secr Defence Clostridium perfringens epsilon toxin vaccines
WO1997044446A1 (en) 1996-05-24 1997-11-27 University Of Maryland At Baltimore Dna vaccines for eliciting a mucosal immune response
ATE346931T1 (de) * 1997-06-20 2006-12-15 Intervet Int Bv Clostridium perfringens impfstoff
WO1999019472A1 (en) 1997-10-16 1999-04-22 University Of Georgia Research Foundation, Inc. Vectors comprising a magnum-specific promoter for avian transgenesis
UA78486C2 (uk) * 1999-12-10 2007-04-10 Хемджен Корпорейшн Композиція для перорального введення птахам та тваринам для лікування або зниження ризику інфекції травного тракту (варіанти), її застосування (варіанти) та спосіб лікування або зниження ризику інфекцій травного тракту (варіанти)
WO2003096812A1 (en) * 2002-04-15 2003-11-27 Washington University Regulated attenuation of live vaccines to enhance cross protective immunogenicity
US20040101531A1 (en) * 2002-04-16 2004-05-27 Roy Curtiss Immunogenic compositions and vaccines comprising carrier bacteria that secrete antigens
EP2028270B9 (en) * 2003-06-18 2012-04-25 Genelux Corporation Modified recombinant vaccinia viruses, uses thereof
US7617795B2 (en) 2004-10-13 2009-11-17 Embrex, Inc. Methods and apparatus for injecting and sampling material through avian egg membranes
BRPI0615593A2 (pt) 2005-08-30 2011-05-24 Commw Scient And Ind Reseaech Organisation liberação bacteriana de polipeptìdeos biologicamente ativos
US20070243212A1 (en) * 2006-03-30 2007-10-18 Embrex, Inc. Methods and compositions for vaccination of poultry
WO2009046449A1 (en) * 2007-10-05 2009-04-09 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacterium capable of eliciting an immune response against enteric pathogens

Also Published As

Publication number Publication date
PT2164862E (pt) 2015-10-29
JP2010529838A (ja) 2010-09-02
CN101903399B (zh) 2014-09-10
WO2008148166A1 (en) 2008-12-11
PL2164862T3 (pl) 2015-12-31
RU2009149378A (ru) 2011-07-20
AU2008258277B2 (en) 2012-07-12
CA2689302A1 (en) 2008-12-11
EP2980100A1 (en) 2016-02-03
CN101903399A (zh) 2010-12-01
US8263088B2 (en) 2012-09-11
JP2014221046A (ja) 2014-11-27
EP2164862A1 (en) 2010-03-24
JP5901115B2 (ja) 2016-04-06
BRPI0812346B1 (pt) 2019-01-22
AU2008258277A1 (en) 2008-12-11
ES2550685T3 (es) 2015-11-11
RU2474587C2 (ru) 2013-02-10
US20100291131A1 (en) 2010-11-18
HUE025717T2 (en) 2016-04-28
EP2164862A4 (en) 2011-11-02
BRPI0812346A2 (pt) 2015-01-27
CA2689302C (en) 2015-08-25
EP2164862B1 (en) 2015-07-22

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