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MX2009008103A - Compuestos anulares fusionados como agonistas parciales de prar-gamma. - Google Patents

Compuestos anulares fusionados como agonistas parciales de prar-gamma.

Info

Publication number
MX2009008103A
MX2009008103A MX2009008103A MX2009008103A MX2009008103A MX 2009008103 A MX2009008103 A MX 2009008103A MX 2009008103 A MX2009008103 A MX 2009008103A MX 2009008103 A MX2009008103 A MX 2009008103A MX 2009008103 A MX2009008103 A MX 2009008103A
Authority
MX
Mexico
Prior art keywords
ppar
gamma
fused ring
partial agonists
ring compounds
Prior art date
Application number
MX2009008103A
Other languages
English (en)
Inventor
Nobuo Cho
Taisuke Tawaraishi
Hiroshi Imoto
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39523585&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009008103(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of MX2009008103A publication Critical patent/MX2009008103A/es

Links

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Communicable Diseases (AREA)

Abstract

La presente invención provee un agente para la prevención o el tratamiento de diabetes, que tiene una acción hipoglucémica superior, y está asociado con menos efectos secundarios tales como aumento de peso corporal, y similares. La presente invención se refiere a un agente para la prevención o el tratamiento de diabetes, que comprende un compuesto representado por (ver fórmula (I')) en donde cada símbolo es como se definió en la descripción, o una de sus sales o uno de sus profármacos.
MX2009008103A 2007-02-09 2008-02-05 Compuestos anulares fusionados como agonistas parciales de prar-gamma. MX2009008103A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007031221 2007-02-09
PCT/JP2008/052217 WO2008099794A1 (en) 2007-02-09 2008-02-05 Fused ring compounds as partial agonists of ppar-gamma

Publications (1)

Publication Number Publication Date
MX2009008103A true MX2009008103A (es) 2009-08-18

Family

ID=39523585

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009008103A MX2009008103A (es) 2007-02-09 2008-02-05 Compuestos anulares fusionados como agonistas parciales de prar-gamma.

Country Status (21)

Country Link
US (2) US20110009384A1 (es)
EP (1) EP2118066A1 (es)
JP (1) JP2010517935A (es)
KR (1) KR20090106660A (es)
CN (1) CN101646653A (es)
AR (1) AR065206A1 (es)
AU (1) AU2008215490A1 (es)
BR (1) BRPI0807014A2 (es)
CA (1) CA2677736A1 (es)
CL (1) CL2008000377A1 (es)
CR (1) CR10991A (es)
DO (1) DOP2009000202A (es)
EA (1) EA200970746A1 (es)
EC (1) ECSP099618A (es)
IL (1) IL200114A0 (es)
MA (1) MA31189B1 (es)
MX (1) MX2009008103A (es)
PE (1) PE20090068A1 (es)
TN (1) TN2009000312A1 (es)
TW (1) TW200838515A (es)
WO (1) WO2008099794A1 (es)

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AR073380A1 (es) 2008-09-25 2010-11-03 Takeda Pharmaceutical Composicion farmaceutica solida. comprimido multicapa
JP5535931B2 (ja) 2008-10-27 2014-07-02 武田薬品工業株式会社 二環性化合物
MX2011005112A (es) * 2008-11-14 2011-06-16 Concert Pharmaceuticals Inc Derivados de dioxopiperidinil-ftalimida sustituida.
US9045453B2 (en) 2008-11-14 2015-06-02 Concert Pharmaceuticals, Inc. Substituted dioxopiperidinyl phthalimide derivatives
JPWO2010076884A1 (ja) 2008-12-29 2012-06-21 武田薬品工業株式会社 新規縮合環化合物およびその用途
WO2010143733A1 (en) 2009-06-09 2010-12-16 Takeda Pharmaceutical Company Limited Novel fused cyclic compound and use thereof
EP2460523B1 (en) 2009-07-28 2017-01-04 Takeda Pharmaceutical Company Limited Tablet
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
NZ603777A (en) 2010-04-27 2013-08-30 Takeda Pharmaceutical Bicyclic compound derivatives and their use as acc inhibitors.
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