ME02877B - Terapeutsko sredstvo za anksiozne poremećaje - Google Patents
Terapeutsko sredstvo za anksiozne poremećajeInfo
- Publication number
- ME02877B ME02877B MEP-2017-233A MEP23317A ME02877B ME 02877 B ME02877 B ME 02877B ME P23317 A MEP23317 A ME P23317A ME 02877 B ME02877 B ME 02877B
- Authority
- ME
- Montenegro
- Prior art keywords
- disorder
- anxiety disorder
- prophylaxis
- pharmaceutically acceptable
- acceptable salt
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
- 208000019901 Anxiety disease Diseases 0.000 claims 4
- 238000011321 prophylaxis Methods 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 150000007979 thiazole derivatives Chemical class 0.000 claims 3
- 238000011282 treatment Methods 0.000 claims 3
- 208000008811 Agoraphobia Diseases 0.000 claims 2
- 208000011688 Generalised anxiety disease Diseases 0.000 claims 2
- 208000021384 Obsessive-Compulsive disease Diseases 0.000 claims 2
- 206010034912 Phobia Diseases 0.000 claims 2
- 206010041250 Social phobia Diseases 0.000 claims 2
- 208000029364 generalized anxiety disease Diseases 0.000 claims 2
- 208000019906 panic disease Diseases 0.000 claims 2
- 208000028173 post-traumatic stress disease Diseases 0.000 claims 2
- 201000001716 specific phobia Diseases 0.000 claims 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Hydrogenated Pyridines (AREA)
Claims (4)
1. Derivat tiazola predstavljen formulom (IC) ili njegova farmaceutski prihvatljiva so, naznačen time što je za upotrebu u tretmanu i/ili profilaksi anksioznog poremećaja.
2. Derivat tiazola ili njegova farmaceutski prihvatljiva so u skladu sa patentnim zahtevom 1, naznačen time što je za upotrebu u tretmanu i/ili profilaksi anksioznog poremećaja izabranog od paničnog poremećaja, agorafobije, opsesivno kompulzivnog poremećaja, socijalne fobije, posttraumatskog stresnog poremećaja, specifične fobije, generalizovanog anksioznog poremećaja.
3. Upotreba derivata tiazola opisanog u patentnom zahtevu 1 ili njegove farmaceutski prihvatljive soli za produkciju sredstva za tretman i/ili profilaksu anksioznog poremećaja.
4. Upotreba u skladu sa patentnim zahtevom 3, naznačena time što je anksiozni poremećaj panični poremećaj, agorafobija, opsesivno kompulzivni poremećaj, socijalna fobija, posttraumatski stresni poremećaj, specifična fobija, generalizovani anksiozni poremećaj.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009202894 | 2009-09-02 | ||
| PCT/JP2010/064989 WO2011027806A1 (ja) | 2009-09-02 | 2010-09-02 | 不安障害治療剤 |
| EP10813754.8A EP2474544B1 (en) | 2009-09-02 | 2010-09-02 | Therapeutic agent for anxiety disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ME02877B true ME02877B (me) | 2018-04-20 |
Family
ID=43649340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MEP-2017-233A ME02877B (me) | 2009-09-02 | 2010-09-02 | Terapeutsko sredstvo za anksiozne poremećaje |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US20120172362A1 (me) |
| EP (1) | EP2474544B1 (me) |
| JP (1) | JP5663485B2 (me) |
| KR (2) | KR20120047311A (me) |
| CN (1) | CN102482271A (me) |
| AU (1) | AU2010290424C1 (me) |
| BR (1) | BR112012004850A2 (me) |
| CA (1) | CA2772922C (me) |
| CL (1) | CL2012000533A1 (me) |
| CY (1) | CY1119483T1 (me) |
| DK (1) | DK2474544T3 (me) |
| DO (1) | DOP2012000056A (me) |
| EA (1) | EA023728B1 (me) |
| ES (1) | ES2643840T3 (me) |
| GE (1) | GEP20156225B (me) |
| HR (1) | HRP20171418T1 (me) |
| HU (1) | HUE036543T2 (me) |
| IL (1) | IL218320A (me) |
| LT (1) | LT2474544T (me) |
| MA (1) | MA33619B1 (me) |
| ME (1) | ME02877B (me) |
| MX (1) | MX2012002529A (me) |
| NZ (1) | NZ598754A (me) |
| PL (1) | PL2474544T3 (me) |
| PT (1) | PT2474544T (me) |
| RS (1) | RS56401B1 (me) |
| SI (1) | SI2474544T1 (me) |
| SM (1) | SMT201700465T1 (me) |
| TN (1) | TN2012000093A1 (me) |
| UA (1) | UA113383C2 (me) |
| WO (1) | WO2011027806A1 (me) |
| ZA (1) | ZA201202347B (me) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3002283T (lt) * | 2003-12-26 | 2017-09-11 | Kyowa Hakko Kirin Co., Ltd. | Tiazolo dariniai |
| MA41090A (fr) * | 2014-12-03 | 2017-10-10 | H Lundbeck As | Antagoniste de a2a faiblement dosé pour le traitement du tdah et de la maladie de parkinson |
| JOP20200093A1 (ar) | 2015-01-09 | 2017-06-16 | Kyowa Kirin Co Ltd | طريقة لإنتاج مشتق ثيازول |
| JO3544B1 (ar) * | 2015-03-19 | 2020-07-05 | Kyowa Kirin Co Ltd | عامل علاجي للاختلال الوظيفي في الفص الجبهي |
| BR112021004999A2 (pt) | 2018-09-17 | 2021-06-08 | Yungjin Pharm. Co., Ltd. | composto e método de inibição de cdk7 em um sujeito |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69331843T2 (de) | 1992-07-08 | 2002-09-26 | Kyowa Hakko Kogyo Co., Ltd. | Xanthine-Derivate als Antidepressiva |
| ES2264210T3 (es) | 1997-09-05 | 2006-12-16 | Kyowa Hakko Kogyo Co., Ltd. | Derivados de xantina para el tratamiento de la isquemia cerebral. |
| US20040152659A1 (en) * | 1999-05-12 | 2004-08-05 | Fujisawa Pharmaceutical Co. Ltd. | Method for the treatment of parkinson's disease comprising administering an A1A2a receptor dual antagonist |
| AU4431000A (en) * | 1999-05-12 | 2000-12-05 | Fujisawa Pharmaceutical Co., Ltd. | Novel use |
| CA2459304A1 (en) * | 2001-09-13 | 2003-03-20 | Schering Corporation | Combination of an adenosine a2a receptor antagonist and an antidepressant or anxiolytic |
| US6620811B2 (en) | 2001-11-19 | 2003-09-16 | Hoffmann-La Roche Inc. | Isonicotin- and nicotinamide derivatives of benzothiazoles |
| EP1631294B1 (en) | 2003-06-10 | 2010-09-15 | Kyowa Hakko Kirin Co., Ltd. | A method of treating an anxiety disorder |
| LT3002283T (lt) * | 2003-12-26 | 2017-09-11 | Kyowa Hakko Kirin Co., Ltd. | Tiazolo dariniai |
| US20100280023A1 (en) * | 2005-06-23 | 2010-11-04 | Kyowa Hakko Kogyo Co., Ltd. | Thiazole derivatives |
| ES2643340T3 (es) | 2005-08-02 | 2017-11-22 | Kyowa Hakko Kirin Co., Ltd. | Agentes para tratar y/o prevenir trastornos del sueño |
| UA110097C2 (uk) * | 2009-09-02 | 2015-11-25 | Терапевтичний агент для лікування розладів настрою |
-
2010
- 2010-02-09 UA UAA201203922A patent/UA113383C2/uk unknown
- 2010-09-02 KR KR1020127008310A patent/KR20120047311A/ko not_active Ceased
- 2010-09-02 CN CN2010800392099A patent/CN102482271A/zh active Pending
- 2010-09-02 CA CA2772922A patent/CA2772922C/en not_active Expired - Fee Related
- 2010-09-02 HR HRP20171418TT patent/HRP20171418T1/hr unknown
- 2010-09-02 DK DK10813754.8T patent/DK2474544T3/en active
- 2010-09-02 RS RS20170966A patent/RS56401B1/sr unknown
- 2010-09-02 KR KR1020177010507A patent/KR20170044768A/ko not_active Ceased
- 2010-09-02 MX MX2012002529A patent/MX2012002529A/es active IP Right Grant
- 2010-09-02 HU HUE10813754A patent/HUE036543T2/hu unknown
- 2010-09-02 LT LTEP10813754.8T patent/LT2474544T/lt unknown
- 2010-09-02 JP JP2011529927A patent/JP5663485B2/ja not_active Expired - Fee Related
- 2010-09-02 SI SI201031544T patent/SI2474544T1/sl unknown
- 2010-09-02 EP EP10813754.8A patent/EP2474544B1/en active Active
- 2010-09-02 BR BR112012004850-3A patent/BR112012004850A2/pt not_active Application Discontinuation
- 2010-09-02 AU AU2010290424A patent/AU2010290424C1/en not_active Ceased
- 2010-09-02 GE GEAP201012648A patent/GEP20156225B/en unknown
- 2010-09-02 EA EA201270360A patent/EA023728B1/ru not_active IP Right Cessation
- 2010-09-02 PT PT108137548T patent/PT2474544T/pt unknown
- 2010-09-02 US US13/393,068 patent/US20120172362A1/en not_active Abandoned
- 2010-09-02 NZ NZ598754A patent/NZ598754A/en not_active IP Right Cessation
- 2010-09-02 WO PCT/JP2010/064989 patent/WO2011027806A1/ja not_active Ceased
- 2010-09-02 PL PL10813754T patent/PL2474544T3/pl unknown
- 2010-09-02 ME MEP-2017-233A patent/ME02877B/me unknown
- 2010-09-02 SM SM20170465T patent/SMT201700465T1/it unknown
- 2010-09-02 ES ES10813754.8T patent/ES2643840T3/es active Active
-
2012
- 2012-02-26 IL IL218320A patent/IL218320A/en active IP Right Grant
- 2012-02-27 TN TNP2012000093A patent/TN2012000093A1/en unknown
- 2012-02-29 CL CL2012000533A patent/CL2012000533A1/es unknown
- 2012-03-01 DO DO2012000056A patent/DOP2012000056A/es unknown
- 2012-03-30 ZA ZA2012/02347A patent/ZA201202347B/en unknown
- 2012-03-30 MA MA34734A patent/MA33619B1/fr unknown
-
2017
- 2017-10-04 CY CY20171101029T patent/CY1119483T1/el unknown
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