[go: up one dir, main page]

NO20064659L - Nye kvarterniserte quinuklidin-estere - Google Patents

Nye kvarterniserte quinuklidin-estere

Info

Publication number
NO20064659L
NO20064659L NO20064659A NO20064659A NO20064659L NO 20064659 L NO20064659 L NO 20064659L NO 20064659 A NO20064659 A NO 20064659A NO 20064659 A NO20064659 A NO 20064659A NO 20064659 L NO20064659 L NO 20064659L
Authority
NO
Norway
Prior art keywords
compounds
new
quinuclidine esters
urological
respiratory
Prior art date
Application number
NO20064659A
Other languages
English (en)
Inventor
Maria Dolors Fernandez Forner
Maria Prat Quinones
Maria Antonia Buil Albero
Original Assignee
Almirall Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Lab filed Critical Almirall Lab
Publication of NO20064659L publication Critical patent/NO20064659L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Nye kinuklidinderivater og farmasøytiske sammensetninger omfattende disse. Forbindelser med formel (I), hvori de ulike substituenter og/eller radikaler har verdiene definert i kravene. Oppfinnelsen angår også en fremgangsmåte for fremstilling av nevnte forbindelser, til farmasøytiske sammensetninger som omfatter disse, så vel som til kombinasjoner av nevnte forbindelser med andre forbindelser, som er aktive i behandlingen av respiratorisk, urologisk eller gastrointestinale forstyrrelser eller sykdommer. Endelig angår oppfinnelsen også anvendelse av forbindelsene med formel (I) for behandling av respiratoriske, urologiske eller gasttointestinale forstyrrelser eller sykdommer.
NO20064659A 2004-03-15 2006-10-13 Nye kvarterniserte quinuklidin-estere NO20064659L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200400638A ES2239546B1 (es) 2004-03-15 2004-03-15 Nuevos esteres de quinuclidina cuaternizados.
PCT/EP2005/002523 WO2005090342A1 (en) 2004-03-15 2005-03-10 New quaternized quinuclidine esters

Publications (1)

Publication Number Publication Date
NO20064659L true NO20064659L (no) 2006-12-13

Family

ID=34955916

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20064659A NO20064659L (no) 2004-03-15 2006-10-13 Nye kvarterniserte quinuklidin-estere

Country Status (30)

Country Link
US (1) US20080214600A1 (no)
EP (1) EP1725552B1 (no)
JP (1) JP2007529444A (no)
KR (1) KR20070003940A (no)
CN (1) CN1930158A (no)
AR (1) AR048004A1 (no)
AT (1) ATE399166T1 (no)
AU (1) AU2005223310A1 (no)
BR (1) BRPI0508177A (no)
CA (1) CA2560157A1 (no)
CY (1) CY1108324T1 (no)
DE (1) DE602005007714D1 (no)
DK (1) DK1725552T3 (no)
EC (1) ECSP066770A (no)
ES (2) ES2239546B1 (no)
HR (1) HRP20080338T3 (no)
IL (1) IL177341A0 (no)
MY (1) MY142036A (no)
NO (1) NO20064659L (no)
NZ (1) NZ548583A (no)
PE (1) PE20060005A1 (no)
PL (1) PL1725552T3 (no)
PT (1) PT1725552E (no)
RS (1) RS50566B (no)
RU (1) RU2382041C2 (no)
SI (1) SI1725552T1 (no)
TW (1) TW200604196A (no)
UA (1) UA88634C2 (no)
WO (1) WO2005090342A1 (no)
ZA (1) ZA200605931B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
GB0424284D0 (en) * 2004-11-02 2004-12-01 Novartis Ag Organic compounds
ES2298049B1 (es) * 2006-07-21 2009-10-20 Laboratorios Almirall S.A. Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano.
EP2121688A1 (en) * 2007-02-15 2009-11-25 Argenta Discovery Ltd Heterocyclic derivatives as m3 muscarinic receptors
PT2197841E (pt) 2007-09-07 2012-01-02 Theravance Inc Compostos contendo guanidina úteis como antagonistas do receptor muscarínico
CA2608561A1 (en) * 2007-10-29 2009-04-29 Carl Paluszkiewicz Motorcycle wind deflector accessory support
JP2011506477A (ja) 2007-12-14 2011-03-03 セラヴァンス， インコーポレーテッド ムスカリン受容体拮抗薬として有用なアミジン含有化合物
EP2100598A1 (en) * 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
US20090326004A1 (en) 2008-06-03 2009-12-31 Ranbaxy Laboratories Limited Muscarinic receptor antagonists
KR101290893B1 (ko) 2009-04-09 2013-07-29 노파르티스 아게 피롤리디늄 염의 제조 방법
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
KR20150092173A (ko) * 2012-12-05 2015-08-12 키에시 파르마슈티시 엣스. 피. 에이. Pde4-억제제로서 페닐에틸피리딘 유도체
CN103755699A (zh) * 2014-01-06 2014-04-30 万特制药(海南)有限公司 一种2-羟基-2,2-二噻吩-2-基乙酸-1-氮杂二环[2,2,2]辛-3(r)-基酯制备方法
CN103755698A (zh) * 2014-01-06 2014-04-30 万特制药(海南)有限公司 一锅法制备阿地溴铵的工艺
KR101511090B1 (ko) 2014-04-24 2015-04-10 고려대학교 산학협력단 염증성 질환의 예방 또는 치료용 약학 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1219606A (en) * 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
US4843074A (en) * 1988-05-17 1989-06-27 Marion Laboratories, Inc. 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts
NO2005012I1 (no) * 1994-12-28 2005-06-06 Debio Rech Pharma Sa Triptorelin og farmasoytisk akseptable salter derav
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
NZ526674A (en) * 2000-12-28 2005-03-24 Almirall Prodesfarma Ag Novel quinuclidine derivatives and medicinal compositions containing the same
JP2005512974A (ja) * 2001-10-17 2005-05-12 ユ セ ベ ソシエテ アノニム キヌクリジン誘導体、その調製方法、及びｍ２及び／又はｍ３ムスカリン受容体阻害剤としてのその使用
ES2204295B1 (es) * 2002-07-02 2005-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de quinuclidina-amida.
AR044134A1 (es) * 2003-05-02 2005-08-24 Novartis Ag Derivados de quinuclidina, metodo de preparacion y composiciones farmaceuticas.

Also Published As

Publication number Publication date
PL1725552T3 (pl) 2008-12-31
ECSP066770A (es) 2006-11-16
NZ548583A (en) 2010-05-28
AU2005223310A1 (en) 2005-09-29
TW200604196A (en) 2006-02-01
MY142036A (en) 2010-08-16
CY1108324T1 (el) 2014-02-12
RS50566B (sr) 2010-05-07
ZA200605931B (en) 2007-11-28
CN1930158A (zh) 2007-03-14
RU2382041C2 (ru) 2010-02-20
EP1725552A1 (en) 2006-11-29
HK1101855A1 (en) 2007-10-26
DK1725552T3 (da) 2008-10-13
SI1725552T1 (sl) 2008-10-31
IL177341A0 (en) 2006-12-10
JP2007529444A (ja) 2007-10-25
UA88634C2 (en) 2009-11-10
ES2307168T3 (es) 2008-11-16
RU2006136085A (ru) 2008-04-27
EP1725552B1 (en) 2008-06-25
DE602005007714D1 (de) 2008-08-07
AR048004A1 (es) 2006-03-15
HRP20080338T3 (hr) 2008-07-31
ES2239546B1 (es) 2006-12-01
ES2239546A1 (es) 2005-09-16
PT1725552E (pt) 2008-09-18
PE20060005A1 (es) 2006-01-28
KR20070003940A (ko) 2007-01-05
ATE399166T1 (de) 2008-07-15
CA2560157A1 (en) 2005-09-29
BRPI0508177A (pt) 2007-08-07
WO2005090342A1 (en) 2005-09-29
US20080214600A1 (en) 2008-09-04

Similar Documents

Publication Publication Date Title
WO2012016186A8 (en) Macrocyclic kinase inhibitors and uses thereof
NO20082709L (no) Kjemiske forbindelser
NO20073719L (no) Kjemiske forbindelser
NO20064659L (no) Nye kvarterniserte quinuklidin-estere
NO20090755L (no) Amino-imidazoloner og deres anvendelse som et medikament for behandling av kognitiv svekkelse, Alzheimers sykdom, neurodegenerering og demens
NO20090166L (no) Amino-imidazoloner og deres anvendelse som et medikament for behandling av kognitiv svekkelse, Alzheimers sykdom, neurodegenerering og demens
UA113051C2 (xx) Гетероциклічні похідні та їх застосування у лікуванні неврологічних розладів
NO20082673L (no) Nye 2-amino-imidazol-4-on forbindelser og deres anvendelse i fremstilling av et medikament som skal brukes til behandling av kognitiv svekkelse, Alzheimers sykdom, neurodegenerasjon og demens
DK2150530T3 (da) Substituerede sulfonamid-derivater
NO20091599L (no) Kjemiske forbindelser
NO20074592L (no) Acetylenyl-pyrazolo-pyrimidinderivater som mGluR2-antagonister
NO20072784L (no) Pyridenkarboksamidderivater for anvendelse som anticancer midler
WO2012162254A8 (en) Inhibitors of lrrk2 kinase activity
WO2008094992A3 (en) 2-aminopyridine derivatives useful as kinase inhibitors
NO20082124L (no) Bifenyloksyeddiksyrederivater for behandling av respiratorisk sykdom
NO20081315L (no) Benzokinazolinderivater og deres anvendelse ved behandling av benlidelser
NO20091683L (no) Kjemiske forbindelser
TW200635899A (en) Chemical compounds
WO2009050242A3 (de) Heterocyclus-substituierte piperazino-dihydrothienopyrimidine
NO20070445L (no) Pyrimidinderivater.
WO2012048129A3 (en) Inhibitors of polo-like kinase
GEP20084452B (en) Sulfonamide derivatives for the treatment of diseases
WO2006099943A8 (de) Amid substituierte 8-n-benzimidazole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
NO20082690L (no) Kjemiske forbindelser
NO20075637L (no) 4-fenyl-5-okso-1,4,5,6,7,8-heksahydrokinolinderivater som medikamenter for behandling av infertilitet

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application