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MD20160058A2 - Pirol[2,3-d]pirimidinil, pirol[2,3-b]pirazinil şi pirol[2,3-d]piridinil acrilamide - Google Patents

Pirol[2,3-d]pirimidinil, pirol[2,3-b]pirazinil şi pirol[2,3-d]piridinil acrilamide Download PDF

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Publication number
MD20160058A2
MD20160058A2 MDA20160058A MD20160058A MD20160058A2 MD 20160058 A2 MD20160058 A2 MD 20160058A2 MD A20160058 A MDA20160058 A MD A20160058A MD 20160058 A MD20160058 A MD 20160058A MD 20160058 A2 MD20160058 A2 MD 20160058A2
Authority
MD
Moldova
Prior art keywords
pyrrolo
pyrimidinyl
acrylamides
pyridinyl
pyrazinyl
Prior art date
Application number
MDA20160058A
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English (en)
Russian (ru)
Other versions
MD4649C1 (ro
MD4649B1 (ro
Inventor
Мэттью Фрэнк Браун
Августин КАЗИМИРО-ГАРСИЯ
Е Чэ
Джотам Уодсворт Коу
Марк Эдвард ФЛАНАГАН
Адам Мэтью Гилберт
Мэттью Меррилл Хэйворд
Джонатан Дэвид ЛАНЖИЛЬ
Джастин Ян МОНТГОМЕРИ
Жан-Батист ТЕЛЬЕЗ
Атли Тораренсен
Райоманд Джал Унвалла
Джон И. ТРУЖИЛЬО
Original Assignee
Pfizer Inc.
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52144776&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MD20160058(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of MD20160058A2 publication Critical patent/MD20160058A2/ro
Publication of MD4649B1 publication Critical patent/MD4649B1/ro
Publication of MD4649C1 publication Critical patent/MD4649C1/ro

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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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Abstract

Prezenta invenţie se referă la pirol[2,3-d]pirimidinil şi pirol[2,3-d]piridinil acrilamide farmaceutic active şi analogii acestora. Astfel de compuşi sunt utili pentru inhibiţia Kinazei Janus (JAK). De asemenea, invenţia se referă la compoziţii, ce cuprinde procedee de preparare a unor asemenea compuşi, şi la metode de tratament şi prevenire a stărilor mediate de JAK.
MDA20160058A 2013-12-05 2014-11-20 Pirol[2,3-d]pirimidinil, pirol[2,3-b]pirazinil şi pirol[2,3-d]piridinil acrilamide MD4649C1 (ro)

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