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MC2049A1 - Nouveaux composes chimiques,procede de preparation desdits composes et compositions pharmaceutiques utiles pour des traitements bronchopulmonaires les contenant - Google Patents

Nouveaux composes chimiques,procede de preparation desdits composes et compositions pharmaceutiques utiles pour des traitements bronchopulmonaires les contenant

Info

Publication number
MC2049A1
MC2049A1 MC892065A MC2065A MC2049A1 MC 2049 A1 MC2049 A1 MC 2049A1 MC 892065 A MC892065 A MC 892065A MC 2065 A MC2065 A MC 2065A MC 2049 A1 MC2049 A1 MC 2049A1
Authority
MC
Monaco
Prior art keywords
sub
acid
phenyl
ethenyl
hydrogen
Prior art date
Application number
MC892065A
Other languages
English (en)
French (fr)
Inventor
Francis Field George
Raymond Vermeulen John
Joseph Zally William
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/366,097 external-priority patent/US5001140A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC2049A1 publication Critical patent/MC2049A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MC892065A 1988-07-15 1989-07-13 Nouveaux composes chimiques,procede de preparation desdits composes et compositions pharmaceutiques utiles pour des traitements bronchopulmonaires les contenant MC2049A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22611288A 1988-07-15 1988-07-15
US33904689A 1989-04-17 1989-04-17
US07/366,097 US5001140A (en) 1989-04-17 1989-06-13 Cycloalkylthiazoles

Publications (1)

Publication Number Publication Date
MC2049A1 true MC2049A1 (fr) 1990-07-17

Family

ID=27397563

Family Applications (1)

Application Number Title Priority Date Filing Date
MC892065A MC2049A1 (fr) 1988-07-15 1989-07-13 Nouveaux composes chimiques,procede de preparation desdits composes et compositions pharmaceutiques utiles pour des traitements bronchopulmonaires les contenant

Country Status (21)

Country Link
EP (1) EP0355353B1 (pt)
JP (1) JPH0737454B2 (pt)
KR (1) KR960010352B1 (pt)
AR (1) AR247737A1 (pt)
AU (1) AU626308B2 (pt)
BG (1) BG60765B2 (pt)
CA (1) CA1333906C (pt)
CS (1) CS417291A3 (pt)
DE (1) DE68913856T2 (pt)
DK (1) DK350989A (pt)
ES (1) ES2052825T3 (pt)
FI (1) FI93953C (pt)
HU (2) HU203087B (pt)
IE (1) IE64011B1 (pt)
IL (1) IL90958A0 (pt)
MC (1) MC2049A1 (pt)
MX (1) MX9203632A (pt)
NO (1) NO175476C (pt)
NZ (1) NZ229928A (pt)
PH (1) PH27275A (pt)
PT (1) PT91179B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5273986A (en) * 1992-07-02 1993-12-28 Hoffmann-La Roche Inc. Cycloalkylthiazoles
US5508408A (en) * 1993-09-10 1996-04-16 Ciba-Geigy Corporation Quinoline compound
EP0643045B1 (de) * 1993-09-10 2000-03-08 Novartis AG Chinolin-Verbindungen als Leukotriene Antagonisten
WO1996008479A1 (en) * 1994-09-13 1996-03-21 F. Hoffmann-La Roche Ag A process of making (e)-4-[3-[2-(4-cycloalkyl-2-thiazolyl)ethenyl]phenyl]amino-2,2-alkyldiyl-4-oxobutanoic acid
WO1996027592A1 (en) * 1995-03-03 1996-09-12 F. Hoffmann-La Roche Ag Polymorphic b form of (e)-4-[[3-[2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxobutanoic acid
WO1996033181A1 (en) * 1995-04-21 1996-10-24 Daiichi Pharmaceutical Co., Ltd. Ethynylthiazole derivative

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62142168A (ja) * 1985-10-16 1987-06-25 Mitsubishi Chem Ind Ltd チアゾ−ル誘導体及びそれを有効成分とするロイコトリエンきつ抗剤

Also Published As

Publication number Publication date
PT91179B (pt) 1995-03-01
KR900001665A (ko) 1990-02-27
DK350989A (da) 1990-01-16
AU626308B2 (en) 1992-07-30
JPH0737454B2 (ja) 1995-04-26
JPH0269468A (ja) 1990-03-08
NO892914D0 (no) 1989-07-14
NO175476C (no) 1994-10-19
AU3828089A (en) 1990-01-18
FI893434A0 (fi) 1989-07-14
FI893434A7 (fi) 1990-01-16
EP0355353A3 (en) 1990-03-07
PT91179A (pt) 1990-02-08
DE68913856T2 (de) 1994-10-20
HU211268A9 (en) 1995-11-28
KR960010352B1 (ko) 1996-07-30
MX9203632A (es) 1992-07-01
CA1333906C (en) 1995-01-10
BG60765B2 (bg) 1996-02-29
DK350989D0 (da) 1989-07-14
IL90958A0 (en) 1990-02-09
IE892294L (en) 1990-01-15
EP0355353A2 (en) 1990-02-28
HUT52489A (en) 1990-07-28
CS417291A3 (en) 1992-09-16
IE64011B1 (en) 1995-06-28
ES2052825T3 (es) 1994-07-16
AR247737A1 (es) 1995-03-31
EP0355353B1 (en) 1994-03-16
FI93953B (fi) 1995-03-15
PH27275A (en) 1993-05-04
NO892914L (no) 1990-01-16
NZ229928A (en) 1992-08-26
FI93953C (fi) 1995-06-26
HU203087B (en) 1991-05-28
NO175476B (no) 1994-07-11
DE68913856D1 (de) 1994-04-21

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