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MA33294B1 - Procédé destiné à la production de poudres de nanoparticules et de microparticules à usage commercial - Google Patents

Procédé destiné à la production de poudres de nanoparticules et de microparticules à usage commercial

Info

Publication number
MA33294B1
MA33294B1 MA34380A MA34380A MA33294B1 MA 33294 B1 MA33294 B1 MA 33294B1 MA 34380 A MA34380 A MA 34380A MA 34380 A MA34380 A MA 34380A MA 33294 B1 MA33294 B1 MA 33294B1
Authority
MA
Morocco
Prior art keywords
biologically active
commercial use
relates
compositions
methods
Prior art date
Application number
MA34380A
Other languages
Arabic (ar)
English (en)
Inventor
Aaron Dodd
Felix Meiser
Adrian Russell
Marck Norret
H William Bosch
Original Assignee
Iceutica Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2009901747A external-priority patent/AU2009901747A0/en
Application filed by Iceutica Pty Ltd filed Critical Iceutica Pty Ltd
Publication of MA33294B1 publication Critical patent/MA33294B1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • AHUMAN NECESSITIES
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    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10Macromolecular compounds
    • AHUMAN NECESSITIES
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    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/12Powders or granules
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/34Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
    • AHUMAN NECESSITIES
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    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A01N37/38Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
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    • A01N39/00Biocides, pest repellants or attractants, or plant growth regulators containing aryloxy- or arylthio-aliphatic or cycloaliphatic compounds, containing the group or, e.g. phenoxyethylamine, phenylthio-acetonitrile, phenoxyacetone
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    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
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    • A01N47/12Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
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    • A01N47/08Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/36Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< directly attached to at least one heterocyclic ring; Thio analogues thereof
    • AHUMAN NECESSITIES
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    • A01N55/00Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
    • A01N55/02Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing metal atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/10Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
    • A01N57/12Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing acyclic or cycloaliphatic radicals
    • AHUMAN NECESSITIES
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    • A01N57/00Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/18Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
    • A01N57/20Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
    • AHUMAN NECESSITIES
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    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/02Sulfur; Selenium; Tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00Shaping or working of foodstuffs characterised by the products
    • A23P10/20Agglomerating; Granulating; Tabletting
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract

La présente invention se rapporte à des procédés destinés à la production de poudres de nanoparticules et de microparticules d'une matière biologiquement active ayant des propriétés de manipulation améliorées qui rendent lesdites poudres adaptées à l'usage commercial, lesdits procédés faisant appel à des opérations de broyage à sec. L'invention se rapporte également à des compositions renfermant lesdites matières, à des médicaments produits au moyen desdites matières biologiquement actives sous forme particulaire et/ou desdites compositions. L'invention concerne en outre des méthodes de traitement d'un animal, y compris d'un être humain, au moyen d'une dose thérapeutiquement efficace de ces matières biologiquement actives administrées par l'intermédiaire desdits médicaments.
MA34380A 2009-04-24 2010-04-23 Procédé destiné à la production de poudres de nanoparticules et de microparticules à usage commercial MA33294B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17230009P 2009-04-24 2009-04-24
AU2009901747A AU2009901747A0 (en) 2009-04-24 Method for the Production of Commercial Nanoparticle and Microparticle Powders
PCT/AU2010/000467 WO2010121323A1 (fr) 2009-04-24 2010-04-23 Procédé destiné à la production de poudres de nanoparticules et de microparticules à usage commercial

Publications (1)

Publication Number Publication Date
MA33294B1 true MA33294B1 (fr) 2012-05-02

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US (5) US20120160944A1 (fr)
EP (1) EP2421511A4 (fr)
JP (3) JP5906181B2 (fr)
KR (3) KR20150021576A (fr)
CN (2) CN102740836A (fr)
AP (1) AP3775A (fr)
AU (1) AU2010239162B2 (fr)
CA (1) CA2759109A1 (fr)
CO (1) CO6470812A2 (fr)
EA (1) EA201171282A1 (fr)
IL (2) IL215875A0 (fr)
MA (1) MA33294B1 (fr)
MX (1) MX344838B (fr)
MY (1) MY179872A (fr)
NZ (1) NZ595902A (fr)
PH (1) PH12015501782A1 (fr)
SG (3) SG10201401712QA (fr)
UA (1) UA110773C2 (fr)
WO (1) WO2010121323A1 (fr)
ZA (1) ZA201108643B (fr)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002308295B2 (en) 2001-03-12 2007-08-23 Intercept Pharmaceuticals, Inc. Steroids as agonists for FXR
WO2008000042A1 (fr) 2006-06-30 2008-01-03 Iceutica Pty Ltd Procédés de préparation de composés biologiquement actifs sous forme de nanoparticules
US20120160944A1 (en) * 2009-04-24 2012-06-28 Aaron Dodd Method for the production of commercial nanoparticle and micro particle powders
NZ595903A (en) * 2009-04-24 2014-03-28 Iceutica Pty Ltd A novel formulation of metaxalone
BRPI1013835B8 (pt) * 2009-04-24 2021-05-25 Iceutica Pty Ltd método para produção de material biologicamente ativo de nanopartícula e/ou micropartícula, composição compreendendo referido material, composição farmacêutica, uso da mesma, e, método para produção de uma composição farmacêutica, de um produto veterinário e de um produto agrícola
NZ595985A (en) * 2009-04-24 2014-07-25 Iceutica Pty Ltd A novel formulation of naproxen
AP2015008955A0 (en) 2009-04-24 2015-12-31 Icuetica Pty Ltd A novel formulation of indomethacin
CN102740835A (zh) * 2009-04-24 2012-10-17 伊休蒂卡有限公司 包封的纳米颗粒在工业规模的制备
WO2012049444A1 (fr) 2010-10-12 2012-04-19 Cipla Limited Composition pharmaceutique
WO2012158380A1 (fr) 2011-05-16 2012-11-22 Drexel University Désagrégation d'amas agrégés de nanodiamant
PH12014500080B1 (en) * 2011-07-08 2023-06-30 Purac Biochem Bv Active formulation for use in feed products
CN104039140B (zh) 2011-08-23 2017-07-21 维弗作物保护公司 拟除虫菊酯配制品
KR101794032B1 (ko) * 2011-09-21 2017-11-07 (주)바이오시네틱스 나노입자 제조방법
CN102418102B (zh) * 2011-12-08 2013-07-31 上海太阳能电池研究与发展中心 用于薄膜太阳电池不锈钢衬底的表面清洗剂及清洗方法
FR2984080B1 (fr) * 2011-12-19 2014-06-13 Solvay Methode pour la fabrication d'une composition parasiticide
EP2793574A4 (fr) 2011-12-22 2015-09-02 Vive Crop Prot Inc Formulations de strobilurine
US10022303B2 (en) * 2012-02-28 2018-07-17 Iceutica Pty Ltd. Inhalable pharmaceutical compositions
JP2014024792A (ja) * 2012-07-26 2014-02-06 Nippon Soda Co Ltd 粉塵爆発性を低減する方法
BR112015010601B1 (pt) * 2012-11-09 2022-07-19 Civitas Therapeutics, Inc. Composição farmacêutica e uso da composição
CN102926274A (zh) * 2012-11-13 2013-02-13 安徽柏邦钛白粉有限公司 造纸专用复合二氧化钛及其制备方法
US20140147521A1 (en) 2012-11-27 2014-05-29 Breathalyzer Equalizer, LLC Breath alcohol equalization composition
US20140179712A1 (en) * 2012-12-21 2014-06-26 Astrazeneca Ab Pharmaceutical formulation of n-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2h-pyrazol-3-yl]-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide
CN103450557B (zh) * 2013-01-24 2015-08-12 长春天成高新纳米复合材料有限公司 一种聚丙烯pp纳米级增强改性颗粒的制备方法
BR112015020572B1 (pt) * 2013-02-28 2022-02-22 Sun Chemical Corporation Processo contínuo para transformar sólido moído em dispersão líquida e aparelho
ES2738182T3 (es) 2013-03-12 2020-01-20 Hercules Llc Composición polimérica revestida de sílice coprocesada
US20150246060A1 (en) 2013-03-15 2015-09-03 Iceutica Inc. Abiraterone Acetate Formulation and Methods of Use
KR20160023641A (ko) * 2013-03-15 2016-03-03 아이슈티카 인코포레이티드 아비라테론 아세테이트 제제
CN106866207A (zh) * 2013-05-06 2017-06-20 麻省理工学院 具有适中离子释放速率的碱金属离子源和形成方法
US20150157646A1 (en) 2013-09-27 2015-06-11 Iceutica Inc. Abiraterone Steroid Formulation
US9468904B2 (en) 2013-12-31 2016-10-18 Ada Carbon Solutions, Llc Sorbent compositions having pneumatic conveyance capabilities
CA2977083A1 (fr) 2014-02-20 2015-08-27 Kambiz Yadidi Preparations de poudre seche a inhaler
US9314767B2 (en) 2014-03-07 2016-04-19 Ada Carbon Solutions, Llc Sorbent compositions having pneumatic conveyance capabilities
KR101476096B1 (ko) * 2014-03-28 2014-12-24 대원제약주식회사 용해도가 향상된 쎄레콕시브의 약제학적 조성물
CN105099721B (zh) * 2014-04-28 2018-12-07 华为技术有限公司 维护组播成员的方法及设备
US9526734B2 (en) 2014-06-09 2016-12-27 Iceutica Pty Ltd. Formulation of meloxicam
CN104069500A (zh) * 2014-06-20 2014-10-01 湖南天地恒一制药有限公司 一种包含乐卡地平的药物组合物
MX2017000141A (es) * 2014-07-03 2017-04-25 Pfizer Nanoparticulas terapeuticas dirigidas y metodos para elaborar y utilizar las mismas.
BR112017001483B8 (pt) * 2014-07-25 2023-02-28 Enzymotec Ltd Composições nutricionais contendo pó de fosfatidilserina
CN107072947A (zh) 2014-07-31 2017-08-18 奥迪托皮克股份有限公司 用于吸入的干粉制剂
BR112017003888B1 (pt) 2014-09-09 2022-11-16 Vectura Limited Método de fabricação de uma formulação de pó seco
PE20180690A1 (es) * 2015-04-27 2018-04-23 Intercept Pharmaceuticals Inc Composiciones de acido obeticolico y metodos de uso
WO2016196401A1 (fr) 2015-05-29 2016-12-08 The Texas A&M University System Compositions antimicrobiennes et anti-inflammatoires
WO2016193900A1 (fr) * 2015-06-05 2016-12-08 Lupin Limited Compositions de diclofénac acide
US9480656B1 (en) 2015-09-28 2016-11-01 King Saud University Method of preparing rosemary nanoparticles and encapsulated rosemary nanoparticles
US10562783B2 (en) * 2015-10-20 2020-02-18 Fujimi Incorporated Processing of alumina
CN105310993A (zh) * 2015-11-17 2016-02-10 深圳信立泰药业股份有限公司 一种含有依折麦布的药物组合物及其制备方法
CN106822005A (zh) * 2015-12-03 2017-06-13 江苏先声药业有限公司 奥贝胆酸组合物及其制备方法
CN113995755A (zh) 2016-02-04 2022-02-01 辛多美制药有限公司 氘代多潘立酮组合物和用于治疗病症的方法
JP7053153B2 (ja) 2016-11-11 2022-04-12 ザ・キュレイターズ・オブ・ザ・ユニバーシティ・オブ・ミズーリ ナノダイヤモンドの塩添加超音波脱凝集
CN107306941A (zh) * 2017-06-21 2017-11-03 深圳千色龙种子健康科技与服务有限公司 拌种剂及其制备方法与应用
US12478612B2 (en) 2017-06-30 2025-11-25 Cindome Pharma, Inc. Deuterated domperidone compositions, methods, and preparation
KR20240125702A (ko) 2017-06-30 2024-08-19 신돔 파마, 인크. 중수소화 돔페리돈 조성물, 방법, 및 제조
CN108113966B (zh) * 2017-08-24 2021-03-16 北京中农华正兽药有限责任公司 一种恩石散去除苦味的制备方法
US11517013B2 (en) 2017-08-25 2022-12-06 Vive Crop Protection Inc. Multi-component, soil-applied, pesticidal compositions
WO2019060797A1 (fr) * 2017-09-22 2019-03-28 Teva Branded Pharmaceutical Products R&D, Inc. Procédé de fabrication de poudres à inhaler
CN109769803A (zh) * 2017-11-14 2019-05-21 北京纳威克生物科技开发有限公司 一种农药聚电解质纳米胶束及其制备方法
CN107960663A (zh) * 2017-11-24 2018-04-27 南通励成生物工程有限公司 碳酸钙营养强化剂及制备方法
US11234928B2 (en) 2017-11-27 2022-02-01 Aska Pharmaceutical Co., Ltd. Powder preparation for nasal administration
EP3459356B1 (fr) * 2018-01-22 2020-06-03 Tessenderlo Group NV Procédé amélioré de production de farine de sang
WO2019199238A1 (fr) * 2018-04-09 2019-10-17 Vet Products Research And Innovation Center Company Limited Minéral inorganique piégé dans une nanoparticules et son procédé de production
KR102033512B1 (ko) 2018-04-27 2019-10-17 주식회사 쓰리에이치굿스 후열 리싸이클 기능을 갖는 히터
KR102086581B1 (ko) 2018-04-27 2020-03-09 주식회사 쓰리에이치굿스 열과 플라즈마를 이용한 공기살균 기능을 갖는 실내용 냉난방기
WO2019232404A1 (fr) * 2018-06-01 2019-12-05 Iterion Therapeutics, Inc. Formulations de tegavivint et composés apparentés
KR102104904B1 (ko) 2018-07-13 2020-05-29 주식회사 쓰리에이치굿스 복사 대류형 냉난방기
CN109646423A (zh) * 2018-12-03 2019-04-19 泓博元生命科技(深圳)有限公司 含nadh的生物高分子纳米球及其制备方法与应用
CN111437260A (zh) * 2019-01-17 2020-07-24 北京万全德众医药生物技术有限公司 用于制备盐酸美金刚固态药物组合物的方法
FR3092727B1 (fr) * 2019-02-19 2023-05-12 Upl Ltd Procédé de préparation de composés de cuivre
WO2020179701A1 (fr) 2019-03-01 2020-09-10 塩野義製薬株式会社 Composition de nanoparticule appauvrie en contaminants et son procédé de production
US20220159971A1 (en) * 2019-03-01 2022-05-26 Hi-Ag Group, Ltd. Plant and Soil Amendment Composition and Method
CN110100816A (zh) * 2019-05-14 2019-08-09 允发化工(上海)有限公司 一种赤霉酸可溶性片剂及其制备方法
WO2021011753A1 (fr) * 2019-07-16 2021-01-21 The Regents Of The University Of Michigan Particules médicamenteuses composites et utilisations associées
RU2726637C1 (ru) * 2019-07-26 2020-07-15 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" (ООО "НВЦ Агроветзащита") Фармацевтическая композиция и способ ее получения
BE1027671B1 (nl) * 2019-08-12 2021-05-10 Anheuser Busch Inbev Sa Poedervormige eiwitsamenstelling
CN110839647B (zh) * 2019-10-24 2021-07-09 惠州市银农科技股份有限公司 一种含吡唑醚菌酯和代森联的杀菌组合物及其制备方法
CN113133970A (zh) 2020-01-17 2021-07-20 美国琛蓝营养制品股份有限公司 一种姜黄素复合物及其制备方法和检测方法
CN111420601A (zh) * 2020-03-30 2020-07-17 宋婷 一种清洁环保生物质取暖颗粒制备设备
WO2021257784A1 (fr) * 2020-06-18 2021-12-23 Verté Therapeutics, Llc Formulations de méloxicam injectables
CN112045195B (zh) * 2020-08-10 2023-05-26 广州有研粉体材料科技有限公司 一种3d打印用金属粉末及金属粉末表面纳米改性方法
WO2022103636A1 (fr) * 2020-11-16 2022-05-19 Orcosa Inc. Utilisation améliorée de cannabinoïdes dans le traitement de la maladie d'alzheimer
US11766042B1 (en) 2021-03-04 2023-09-26 MonarchChem, LLC Organic contact herbicide and method of use thereof
CN113649135A (zh) * 2021-07-27 2021-11-16 惠州市银农科技股份有限公司 基于研磨补偿介质的热敏性原药研磨方法和农药制剂
KR102771921B1 (ko) 2022-03-21 2025-02-25 강경림 태백토와 태백암 성분이 혼합된 미립자 분말 제조 방법
CN120322221A (zh) * 2022-06-21 2025-07-15 好利安科技有限公司 用于吸入的包含糖和脂质复合颗粒的结晶药物组合物及其制备方法
CN116063127B (zh) * 2023-02-10 2024-06-25 河北冀森生物科技有限公司 一种水溶肥高效防结块剂及其制备方法与应用
US20240341342A1 (en) * 2023-04-11 2024-10-17 Paul Knox High efficancy hydration composion, production method, and use.
CN116282150B (zh) * 2023-04-14 2024-07-30 贵州华星冶金有限公司 一种空心三氧化二锑的制备方法
US11832614B1 (en) 2023-04-28 2023-12-05 King Faisal University Method of inhibiting mycotoxin growth using Arthrospira platensis nanoparticles
KR102699079B1 (ko) * 2023-10-30 2024-08-26 (주)세인비에스 비타민 a, d3, e를 함유한 나노제품 및 이를 이용한 동물용 영양제
CN119000958B (zh) * 2024-10-18 2025-01-17 广州医科大学附属口腔医院(广州医科大学羊城医院) 一种正畸透明矫治器中六氯丁二烯和全氟类化合物的检测方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3172546A (en) * 1961-05-19 1965-03-09 Union Carbide Corp Size reduction of biological substances
JP2642486B2 (ja) * 1989-08-04 1997-08-20 田辺製薬株式会社 難溶性薬物の超微粒子化法
AU660852B2 (en) * 1992-11-25 1995-07-06 Elan Pharma International Limited Method of grinding pharmaceutical substances
JP4117811B2 (ja) * 1997-04-22 2008-07-16 日本化薬株式会社 フルタミド製剤及びその製法
SA99191255B1 (ar) * 1998-11-30 2006-11-25 جي دي سيرل اند كو مركبات سيليكوكسيب celecoxib
JP2004331500A (ja) * 2001-02-16 2004-11-25 Dainippon Pharmaceut Co Ltd 血中濃度制御製剤
JP2004099442A (ja) * 2002-09-04 2004-04-02 Nisshin Pharma Inc 難溶性薬物含有製剤およびその製造方法
US20040121003A1 (en) * 2002-12-19 2004-06-24 Acusphere, Inc. Methods for making pharmaceutical formulations comprising deagglomerated microparticles
US8512727B2 (en) * 2003-03-03 2013-08-20 Alkermes Pharma Ireland Limited Nanoparticulate meloxicam formulations
KR20060024927A (ko) * 2004-09-15 2006-03-20 씨제이 주식회사 기계적 분쇄법에 의한 미크론 사이즈 인삼 분말의제조방법
WO2006041843A2 (fr) * 2004-10-04 2006-04-20 Dr. Reddy's Laboratories Ltd. Forme posologique pharmaceutique comprenant meloxicam
NZ555719A (en) * 2004-12-31 2010-11-26 Iceutica Pty Ltd Nanoparticle composition and methods for synthesis thereof
EP1973523A2 (fr) * 2005-12-15 2008-10-01 Acusphere, Inc. Fabrication de preparations pharmaceutiques a base de particules pour administration pulmonaire ou nasale
JP2007169226A (ja) * 2005-12-22 2007-07-05 Ono Pharmaceut Co Ltd 固体分散体
AU2007235002A1 (en) * 2006-04-07 2007-10-18 Allergan, Inc. Compositions including relatively water insoluble/unwettable drugs and methods for using same
US8420122B2 (en) * 2006-04-28 2013-04-16 Merck Sharp & Dohme Corp. Process for the precipitation and isolation of 6,6-dimethyl-3-aza-bicyclo [3.1.0] hexane-amide compounds by controlled precipitation and pharmaceutical formulations containing same
WO2008000042A1 (fr) * 2006-06-30 2008-01-03 Iceutica Pty Ltd Procédés de préparation de composés biologiquement actifs sous forme de nanoparticules
AR065802A1 (es) * 2007-03-22 2009-07-01 Schering Corp Formulaciones de comprimidos que contienen sales de 8- [( 1- ( 3,5- bis- (trifluorometil) fenil) -etoxi ) - metil) -8- fenil -1, 7- diaza- spiro [ 4,5] decan -2- ona y comprimidos elaborados a partir de estas
US8568696B2 (en) * 2008-08-06 2013-10-29 Indiana Nanotech Llc Grinding method for the manipulation or preservation of calcium phosphate hybrid properties
US20120160944A1 (en) * 2009-04-24 2012-06-28 Aaron Dodd Method for the production of commercial nanoparticle and micro particle powders
SG175309A1 (en) * 2009-04-24 2011-11-28 Iceutica Pty Ltd Production of encapsulated nanoparticles at high volume fractions

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