There are 6 ways to get from Mayo Clinic to Chicago O'Hare Airport (ORD) by plane, bus, subway, rideshare, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Rochester to Chicago O'Hare International Airport
best- Fly from Rochester (RST) to Chicago O'Hare International Airport (ORD)plane RST - ORD
2h 55m$36–277Bus to Minneapolis–Saint Paul International Airport, fly to Chicago Midway International Airport, subway
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Chicago Midway International Airport (MDW)plane MSP - MDW
- Take the subway from Clark/Lake to O'Haresubway
5h 30m$114–460Bus
- Take the bus from Rochester to Madisonbus Jefferson Lines 965
- Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus Van Galder
7h 59m$77–124Airport Transfer
- Take the rideshare from Mayo Clinic to Chicago O'Hare International Airport (ORD)333.6 mi
5h 27mDrive 333.6 mi
- Drive from Mayo Clinic to Chicago O'Hare Airport (ORD)car 333.6 mi
5h 27m$61–88Bus to Minneapolis–Saint Paul International Airport, fly to Chicago O'Hare International Airport
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Chicago O'Hare International Airport (ORD)plane MSP - ORD
3h 55m$280–800
Mayo Clinic to Chicago O'Hare Airport (ORD) by foot and bus
Comparing Your Travel Options
The cheapest way to get from Mayo Clinic to Chicago O'Hare Airport (ORD) is to drive which costs $60 - $90 and takes 5h 27m.
The fastest way to get from Mayo Clinic to Chicago O'Hare Airport (ORD) is to fly which takes 2h 55m and costs $35 - $280.
No, there is no direct bus from Mayo Clinic to Chicago O'Hare Airport (ORD). However, there are services departing from Rochester and arriving at O'Hare International Airport - Terminal 1 Departures via 250 N. Lake St - Madison UW Campus. The journey, including transfers, takes approximately 7h 59m.
The distance between Mayo Clinic and Chicago O'Hare Airport (ORD) is 278 miles. The road distance is 335.6 miles.
The best way to get from Mayo Clinic to Chicago O'Hare Airport (ORD) without a car is to bus which takes 7h 59m and costs $75 - $130.
It takes approximately 2h 55m to get from Mayo Clinic to Chicago O'Hare Airport (ORD), including transfers.
Mayo Clinic to Chicago O'Hare Airport (ORD) bus services, operated by Jefferson Lines, depart from Rochester station.
The best way to get from Mayo Clinic to Chicago O'Hare Airport (ORD) is to fly which takes 2h 55m and costs $35 - $280. Alternatively, you can bus, which costs $75 - $130 and takes 7h 59m.
Mayo Clinic to Chicago O'Hare Airport (ORD) bus services, operated by Jefferson Lines, arrive at Madison station.
Yes, the driving distance between Mayo Clinic to Chicago O'Hare Airport (ORD) is 336 miles. It takes approximately 5h 27m to drive from Mayo Clinic to Chicago O'Hare Airport (ORD).
What companies run services between Mayo Clinic, MN, USA and Chicago O'Hare Airport (ORD), USA?
American Airlines flies from Rochester (RST) to Chicago O'Hare International Airport (ORD) 3 times a day. Alternatively, you can take a vehicle from Mayo Clinic to O'Hare International Airport - Terminal 1 Departures via Rochester, Madison, and 250 N. Lake St - Madison UW Campus in around 7h 59m.
- Website
- delta.com
Flights from Minneapolis–Saint Paul International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $60–400
Flights from Minneapolis–Saint Paul International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $45–310
- Website
- southwest.com
Flights from Minneapolis–Saint Paul International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $60–400
- Website
- aa.com
Flights from Rochester to Chicago O'Hare International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $35–240
Flights from Minneapolis–Saint Paul International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $45–310
- Website
- united.com
Flights from Minneapolis–Saint Paul International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $45–310
- Website
- suncountry.com
Flights from Minneapolis–Saint Paul International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 38m
- When
- Friday and Thursday
- Estimated price
- $45–310
- Phone
- +1 888-968-7282
- Website
- Chicago Transit Authority
Subway from Clark/Lake to O'Hare
- Ave. Duration
- 42 min
- Frequency
- Every 10 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Rochester to Madison
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
- Phone
- +1 (866) 912 - 6224
- questions@coachusa.com
- Website
- Rockland Coaches
Bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departures
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- $23–50
- Schedules at
- Rockland Coaches
- Adult
- $23–50
- Website
- https://www.mozio.com
Rideshare from Mayo Clinic to Chicago O'Hare International Airport (ORD)
- Ave. Duration
- 5h 27m
- Frequency
- On demand
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There are 305+ hotels available in Chicago O'Hare Airport (ORD).
Check out Blablacar's carpooling service for rideshare options between Mayo Clinic and Chicago O'Hare Airport (ORD). A great option if you don't have a driver's licence or want to avoid public transport.