There are 3 ways to get from Mayo Clinic to Ottumwa by bus (Greyhound), car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Rochester to St. Paulbus
- Take the bus from Saint Paul Union Depot to Des Moinesbus
- Take the bus from Des Moines to Ottumwa Bus Stopbus
9h 58m$83–126Drive 226.4 mi
cheapest- Drive from Mayo Clinic to Ottumwacar 226.4 mi
4h 56m$42–60Fly, bus
- Fly from Rochester (RST) to Des Moines (DSM)plane RST - DSM
- Take the bus from Des Moines to Ottumwa Bus Stopbus
8h 24m$117–590
Mayo Clinic to Ottumwa by foot and bus
Comparing Your Travel Options
The cheapest way to get from Mayo Clinic to Ottumwa is to drive which costs $40 - $60 and takes 4h 56m.
The fastest way to get from Mayo Clinic to Ottumwa is to drive which takes 4h 56m and costs $40 - $60.
No, there is no direct bus from Mayo Clinic to Ottumwa. However, there are services departing from Rochester and arriving at Ottumwa Bus Stop via Saint Paul Union Depot and Des Moines. The journey, including transfers, takes approximately 9h 58m.
The distance between Mayo Clinic and Ottumwa is 411 miles. The road distance is 227.7 miles.
The best way to get from Mayo Clinic to Ottumwa without a car is to bus which takes 9h 58m and costs $80 - $130.
It takes approximately 9h 58m to get from Mayo Clinic to Ottumwa, including transfers.
Mayo Clinic to Ottumwa bus services, operated by Jefferson Lines, depart from Rochester station.
Mayo Clinic to Ottumwa bus services, operated by Jefferson Lines, arrive at St. Paul station.
Yes, the driving distance between Mayo Clinic to Ottumwa is 228 miles. It takes approximately 4h 56m to drive from Mayo Clinic to Ottumwa.
There are eight+ hotels available in Ottumwa.
What companies run services between Mayo Clinic, MN, USA and Ottumwa, IA, USA?
You can take a vehicle from Mayo Clinic to Ottumwa Bus Stop via Rochester, Saint Paul Union Depot, and Des Moines in around 9h 58m.
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Rochester to St. Paul
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Saint Paul Union Depot to Des Moines
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- $40–65
- Website
- Greyhound
Bus from Des Moines to Ottumwa Bus Stop
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $14–22
- Website
- Greyhound
Bus from Des Moines to Ottumwa Bus Stop
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $14–22
- Website
- Greyhound
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