| Phenylalanine hydroxylase: function, structure, and regulation MI Flydal, A Martinez IUBMB life 65 (4), 341-349, 2013 | 294 | 2013 |
| Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation MT Bueno-Carrasco, J Cuéllar, MI Flydal, C Santiago, TA Kråkenes, ... Nature communications 13 (1), 74, 2022 | 96 | 2022 |
| Structure of phenylalanine hydroxylase from Colwellia psychrerythraea 34H, a monomeric cold active enzyme with local flexibility around the active site and high overall stability HKS Leiros, AL Pey, M Innselset, E Moe, I Leiros, IH Steen, A Martinez Journal of Biological Chemistry 282 (30), 21973-21986, 2007 | 91 | 2007 |
| Arc is a flexible modular protein capable of reversible self-oligomerization C Myrum, A Baumann, HJ Bustad, MI Flydal, V Mariaule, S Alvira, ... Biochemical Journal 468 (1), 145-158, 2015 | 89 | 2015 |
| Structure of full-length human phenylalanine hydroxylase in complex with tetrahydrobiopterin MI Flydal, M Alcorlo-Pagés, FG Johannessen, S Martínez-Caballero, ... Proceedings of the National Academy of Sciences 116 (23), 11229-11234, 2019 | 74 | 2019 |
| Brain catecholamine depletion and motor impairment in a Th knock-in mouse with type B tyrosine hydroxylase deficiency G Korner, D Noain, M Ying, M Hole, MI Flydal, T Scherer, G Allegri, ... Brain 138 (10), 2948-2963, 2015 | 47 | 2015 |
| Arc self‐association and formation of virus‐like capsids are mediated by an N‐terminal helical coil motif MS Eriksen, O Nikolaienko, EI Hallin, S Grødem, HJ Bustad, MI Flydal, ... The FEBS journal 288 (9), 2930-2955, 2021 | 40 | 2021 |
| Stable preparations of tyrosine hydroxylase provide the solution structure of the full-length enzyme MT Bezem, A Baumann, L Skjærven, R Meyer, P Kursula, A Martinez, ... Scientific reports 6 (1), 30390, 2016 | 39 | 2016 |
| Regulation of tyrosine hydroxylase is preserved across different homo-and heterodimeric 14-3-3 proteins S Ghorbani, A Fossbakk, A Jorge-Finnigan, MI Flydal, J Haavik, R Kleppe Amino acids 48 (5), 1221-1229, 2016 | 32 | 2016 |
| Phenylalanine Hydroxylase from Legionella pneumophila Is a Thermostable Enzyme with a Major Functional Role in Pyomelanin Synthesis MI Flydal, CH Chatfield, H Zheng, FF Gunderson, O Aubi, NP Cianciotto, ... Public Library of Science 7 (9), e46209, 2012 | 31 | 2012 |
| Personalized medicine to improve treatment of dopa-responsive dystonia—a focus on tyrosine hydroxylase deficiency G Nygaard, PD Szigetvari, AK Grindheim, P Ruoff, A Martinez, J Haavik, ... Journal of Personalized Medicine 11 (11), 1186, 2021 | 24 | 2021 |
| Levalbuterol lowers the feedback inhibition by dopamine and delays misfolding and aggregation in tyrosine hydroxylase MI Flydal, TA Kråkenes, MDS Tai, MPA Tran, K Teigen, A Martinez Biochimie 183, 126-132, 2021 | 20 | 2021 |
| Superstoichiometric binding of L-Phe to phenylalanine hydroxylase from Caenorhabditis elegans: evolutionary implications MI Flydal, TC Mohn, AL Pey, J Siltberg-Liberles, K Teigen, A Martinez Amino Acids 39 (5), 1463-1475, 2010 | 19 | 2010 |
| The Host-Pathogen interaction of Human Cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains SMO Solbak, V Wray, O Horvli, AJ Raae, MI Flydal, P Henklein, ... BMC structural biology 11 (1), 49, 2011 | 18 | 2011 |
| Discovery of a Specific Inhibitor of Pyomelanin Synthesis in Legionella pneumophila O Aubi, MI Flydal, H Zheng, L Skjærven, I Rekand, HKS Leiros, BE Haug, ... Journal of medicinal chemistry 58 (21), 8402-8412, 2015 | 17 | 2015 |
| Inhibition of the human Hsc70 system by small ligands as a potential anticancer approach L Dublang, J Underhaug, MI Flydal, L Velasco-Carneros, JD Maréchal, ... Cancers 13 (12), 2936, 2021 | 15 | 2021 |
| New perspectives for pharmacological chaperoning treatment in methylmalonic aciduria cblB type S Brasil, A Briso-Montiano, A Gámez, J Underhaug, MI Flydal, L Desviat, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (2), 640-648, 2018 | 12 | 2018 |
| Differential scanning fluorimetry in the screening and validation of pharmacological chaperones for soluble and membrane proteins SI Støve, MI Flydal, E Hausvik, J Underhaug, A Martinez Protein Homeostasis Diseases, 329-341, 2020 | 9 | 2020 |
| Structural recognition and stabilization of tyrosine hydroxylase by the J-domain protein DNAJC12 MDS Tai, L Ochoa, MI Flydal, L Velasco-Carneros, J Muntaner, ... Nature Communications 16 (1), 1-21, 2025 | 7 | 2025 |
| Structural and thermodynamic insight into phenylalanine hydroxylase from the human pathogen Legionella pneumophila HKS Leiros, MI Flydal, A Martinez FEBS Open bio 3, 370-378, 2013 | 6 | 2013 |
Aurora MartinezProfessor ved University of BergenVerified email at uib.no
