| Unravelling biological macromolecules with cryo-electron microscopy R Fernandez-Leiro, SHW Scheres Nature 537 (7620), 339, 2016 | 526 | 2016 |
| A pipeline approach to single-particle processing in RELION R Fernandez-Leiro, SHW Scheres Biological Crystallography 73 (6), 496-502, 2017 | 314 | 2017 |
| SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care C Gutmann, K Takov, SA Burnap, B Singh, H Ali, K Theofilatos, E Reed, ... Nature communications 12 (1), 3406, 2021 | 170 | 2021 |
| Architecture of the mycobacterial type VII secretion system N Famelis, A Rivera-Calzada, G Degliesposti, M Wingender, N Mietrach, ... Nature 576 (7786), 321-325, 2019 | 147 | 2019 |
| Structure and organization of heteromeric AMPA-type glutamate receptors B Herguedas, J García-Nafría, O Cais, R Fernández-Leiro, J Krieger, ... Science 352 (6285), aad3873, 2016 | 139 | 2016 |
| Structural basis of specificity in tetrameric Kluyveromyces lactis β-galactosidase Á Pereira-Rodríguez, R Fernández-Leiro, MI González-Siso, ME Cerdán, ... Journal of structural biology 177 (2), 392-401, 2012 | 136 | 2012 |
| cryo-EM structures of the E. coli replicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease and τ R Fernandez-Leiro, J Conrad, SHW Scheres, MH Lamers Elife 4, e11134, 2015 | 105 | 2015 |
| Structure of full-length human phenylalanine hydroxylase in complex with tetrahydrobiopterin MI Flydal, M Alcorlo-Pagés, FG Johannessen, S Martínez-Caballero, ... Proceedings of the National Academy of Sciences 116 (23), 11229-11234, 2019 | 74 | 2019 |
| Self-correcting mismatches during high-fidelity DNA replication R Fernandez-Leiro, J Conrad, JC Yang, SMV Freund, SHW Scheres, ... Nature structural & molecular biology 24 (2), 140-143, 2017 | 69 | 2017 |
| Polymerization and editing modes of a high-fidelity DNA polymerase are linked by a well-defined path T Dodd, M Botto, F Paul, R Fernandez-Leiro, MH Lamers, I Ivanov Nature communications 11 (1), 5379, 2020 | 61 | 2020 |
| Assembly of the asymmetric human γ-tubulin ring complex by RUVBL1-RUVBL2 AAA ATPase F Zimmermann, M Serna, A Ezquerra, R Fernandez-Leiro, O Llorca, ... Science Advances 6 (51), eabe0894, 2020 | 60 | 2020 |
| Secretion and properties of a hybrid Kluyveromyces lactis-Aspergillus niger β-galactosidase ÁP Rodríguez, RF Leiro, MC Trillo, ME Cerdán, MIG Siso, M Becerra Microbial Cell Factories 5 (1), 41, 2006 | 60 | 2006 |
| Structural analysis of Saccharomyces cerevisiae α-galactosidase and its complexes with natural substrates reveals new insights into substrate specificity of GH27 glycosidases R Fernandez-Leiro, A Pereira-Rodriguez, ME Cerdán, M Becerra, ... Journal of Biological Chemistry 285 (36), 28020-28033, 2010 | 55 | 2010 |
| Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM H Muñoz-Hernández, M Pal, CF Rodríguez, R Fernandez-Leiro, ... Science advances 5 (5), eaaw1616, 2019 | 54 | 2019 |
| The selection process of licensing a DNA mismatch for repair R Fernandez-Leiro, D Bhairosing-Kok, V Kunetsky, C Laffeber, ... Nature Structural & Molecular Biology 28 (4), 373-381, 2021 | 47 | 2021 |
| Emerging two-dimensional crystallization of cucurbit [8] uril complexes: From supramolecular polymers to nanofibers J Barrio, J Liu, RA Brady, CSY Tan, S Chiodini, M Ricci, ... Journal of the American Chemical Society 141 (36), 14021-14025, 2019 | 45 | 2019 |
| Widespread displacement of DNA‐and RNA‐binding factors underlies toxicity of arginine‐rich cell‐penetrating peptides V Lafarga, O Sirozh, I Díaz‐López, A Galarreta, M Hisaoka, E Zarzuela, ... The EMBO Journal 40 (13), e103311, 2021 | 38 | 2021 |
| The cryo-EM Structure of Thermotoga maritima β-Galactosidase: Quaternary Structure Guides Protein Engineering S Míguez Amil, E Jiménez-Ortega, M Ramírez-Escudero, ... ACS Chemical Biology 15 (1), 179-188, 2019 | 27 | 2019 |
| Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM A Lopez-Perrote, N Hug, A González-Corpas, CF Rodríguez, M Serna, ... Elife 9, e63042, 2020 | 18 | 2020 |
| Ixr1p regulates oxygen-dependent HEM13 transcription R Castro-Prego, M Lamas-Maceiras, P Soengas, R Fernandez-Leiro, ... FEMS yeast research 10 (3), 309-321, 2010 | 18 | 2010 |
Sjors ScheresMRC Laboratory of Molecular BiologyVerified email at mrc-lmb.cam.ac.uk
