| Big data in basic and translational cancer research P Jiang, S Sinha, K Aldape, S Hannenhalli, C Sahinalp, E Ruppin Nature Reviews Cancer 22 (11), 625-639, 2022 | 256 | 2022 |
| Synthetic lethality-mediated precision oncology via the tumor transcriptome JS Lee, NU Nair, G Dinstag, L Chapman, Y Chung, K Wang, S Sinha, ... Cell 184 (9), 2487-2502. e13, 2021 | 148 | 2021 |
| A deep-learning framework to predict cancer treatment response from histopathology images through imputed transcriptomics DT Hoang, G Dinstag, ED Shulman, LC Hermida, DS Ben-Zvi, E Elis, ... Nature cancer 5 (9), 1305-1317, 2024 | 99 | 2024 |
| AXL and error-prone DNA replication confer drug resistance and offer strategies to treat EGFR-mutant lung cancer A Noronha, N Belugali Nataraj, JS Lee, B Zhitomirsky, Y Oren, S Oster, ... Cancer discovery 12 (11), 2666-2683, 2022 | 95 | 2022 |
| In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression S Sinha, K Cheng, AA Schäffer, K Aldape, E Schiff, E Ruppin Molecular systems biology 16 (7), MSB209628, 2020 | 93* | 2020 |
| The GPCR–Gαs–PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure VH Wu, BS Yung, F Faraji, R Saddawi-Konefka, Z Wang, AT Wenzel, ... Nature immunology 24 (8), 1318-1330, 2023 | 77 | 2023 |
| PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumors S Sinha, R Vegesna, S Mukherjee, AV Kammula, SR Dhruba, W Wu, ... Nature Cancer 5 (6), 938-952, 2024 | 72 | 2024 |
| Identification of drugs associated with reduced severity of COVID-19–a case-control study in a large population A Israel, AA Schäffer, A Cicurel, K Cheng, S Sinha, E Schiff, I Feldhamer, ... Elife 10, e68165, 2021 | 72* | 2021 |
| A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing S Sinha, K Barbosa, K Cheng, MDM Leiserson, P Jain, A Deshpande, ... Nature communications 12 (1), 6512, 2021 | 67* | 2021 |
| A Division of Labor between YAP and TAZ in Non–Small Cell Lung Cancer M Shreberk-Shaked, B Dassa, S Sinha, S Di Agostino, I Azuri, ... Cancer research 80 (19), 4145-4157, 2020 | 65 | 2020 |
| Clinically oriented prediction of patient response to targeted and immunotherapies from the tumor transcriptome G Dinstag, ED Shulman, E Elis, DS Ben-Zvi, O Tirosh, E Maimon, ... Med 4 (1), 15-30. e8, 2023 | 55 | 2023 |
| Higher prevalence of homologous recombination deficiency in tumors from African Americans versus European Americans S Sinha, KA Mitchell, A Zingone, E Bowman, N Sinha, AA Schäffer, ... Nature Cancer 1 (1), 112-121, 2020 | 52 | 2020 |
| Dysregulation of HNF1B/Clusterin axis enhances disease progression in a highly aggressive subset of pancreatic cancer patients S Yang, W Tang, A Azizian, J Gaedcke, P Ströbel, L Wang, H Cawley, ... Carcinogenesis 43 (12), 1198-1210, 2022 | 51 | 2022 |
| Immune determinants of the association between tumor mutational burden and immunotherapy response across cancer types N Sinha, S Sinha, C Valero, AA Schäffer, K Aldape, K Litchfield, TA Chan, ... Cancer research 82 (11), 2076-2083, 2022 | 45 | 2022 |
| Genome‐scale metabolic modeling reveals SARS‐CoV‐2‐induced metabolic changes and antiviral targets K Cheng, L Martin‐Sancho, LR Pal, Y Pu, L Riva, X Yin, S Sinha, NU Nair, ... Molecular systems biology 17 (11), e10260, 2021 | 45* | 2021 |
| Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans KA Mitchell, N Nichols, W Tang, J Walling, H Stevenson, M Pineda, ... Nature communications 10 (1), 5735, 2019 | 33 | 2019 |
| MCP-1/CCR2 axis inhibition sensitizes the brain microenvironment against melanoma brain metastasis progression S Pozzi, A Scomparin, D Ben-Shushan, E Yeini, P Ofek, AD Nahmad, ... JCI insight 7 (17), e154804, 2022 | 29 | 2022 |
| The landscape of receptor-mediated precision cancer combination therapy via a single-cell perspective S Ahmadi, P Sukprasert, R Vegesna, S Sinha, F Schischlik, N Artzi, ... Nature communications 13 (1), 1613, 2022 | 28 | 2022 |
| Whole-exome profiling of NSCLC among African Americans RF Arauz, JS Byun, M Tandon, S Sinha, S Kuhn, S Taylor, A Zingone, ... Journal of Thoracic Oncology 15 (12), 1880-1892, 2020 | 28 | 2020 |
| Prediction of cancer treatment response from histopathology images through imputed transcriptomics DT Hoang, G Dinstag, LC Hermida, DS Ben-Zvi, E Elis, K Caley, ... Research Square, rs. 3. rs-3193270, 2023 | 23* | 2023 |
Eytan RuppinTranslational Research Institute and Jim and Eleanor Randall Department of Surgery, Cedars-SinaiVerified email at cshs.org
