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| ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage R Maya, M Balass, ST Kim, D Shkedy, JFM Leal, O Shifman, M Moas, ... Genes & development 15 (9), 1067-1077, 2001 | 1000 | 2001 |
| Role of redox potential and reactive oxygen species in stress signaling V Adler, Z Yin, KD Tew, Z Ronai Oncogene 18 (45), 6104-6111, 1999 | 893 | 1999 |
| MEKK1/JNK signaling stabilizes and activates p53 SY Fuchs, V Adler, MR Pincus, Z Ronai Proceedings of the National Academy of Sciences 95 (18), 10541-10546, 1998 | 713 | 1998 |
| The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults P Zacchi, M Gostissa, T Uchida, C Salvagno, F Avolio, S Volinia, Z Ronai, ... Nature 419 (6909), 853-857, 2002 | 542 | 2002 |
| Siah2 regulates stability of prolyl-hydroxylases, controls HIF1α abundance, and modulates physiological responses to hypoxia K Nakayama, IJ Frew, M Hagensen, M Skals, H Habelhah, A Bhoumik, ... Cell 117 (7), 941-952, 2004 | 532 | 2004 |
| Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation H Xiong, D Wang, L Chen, YS Choo, H Ma, C Tang, K Xia, W Jiang, ... The Journal of clinical investigation 119 (3), 650-660, 2009 | 509 | 2009 |
| JNK targets p53 ubiquitination and degradation in nonstressed cells SY Fuchs, V Adler, T Buschmann, Z Yin, X Wu, SN Jones, Z Ronai Genes & development 12 (17), 2658-2663, 1998 | 492 | 1998 |
| Ubiquitin ligases in oncogenic transformation and cancer therapy D Senft, J Qi, ZA Ronai Nature Reviews Cancer 18 (2), 69-88, 2018 | 477 | 2018 |
| Cellular thiols and reactive oxygen species in drug-induced apoptosis W Davis Jr, Z Ronai, KD Tew The Journal of pharmacology and experimental therapeutics 296 (1), 1-6, 2001 | 462 | 2001 |
| Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect DA Scott, AD Richardson, FV Filipp, CA Knutzen, GG Chiang, ZA Ronai, ... Journal of Biological Chemistry 286 (49), 42626-42634, 2011 | 445 | 2011 |
| Recruitment of a ROC1–CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of IκBα P Tan, SY Fuchs, A Chen, K Wu, C Gomez, Z Ronai, ZQ Pan Molecular cell 3 (4), 527-533, 1999 | 436 | 1999 |
| Jun NH2-Terminal Kinase Phosphorylation of p53 on Thr-81 Is Important for p53 Stabilization and Transcriptional Activities in Response to Stress T Buschmann, O Potapova, A Bar-Shira, VN Ivanov, SY Fuchs, ... Molecular and cellular biology 21 (8), 2743-2754, 2001 | 434 | 2001 |
| BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma J Dong, RG Phelps, R Qiao, S Yao, O Benard, Z Ronai, SA Aaronson Cancer research 63 (14), 3883-3885, 2003 | 409 | 2003 |
| Glutathione S-transferase P1–1 (GSTP1–1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus T Wang, P Arifoglu, Z Ronai, KD Tew Journal of Biological Chemistry 276 (24), 20999-21003, 2001 | 398 | 2001 |
| p53–Mdm2—the affair that never ends D Alarcon-Vargas, Z Ronai Carcinogenesis 23 (4), 541-547, 2002 | 393 | 2002 |
| Emerging roles of ATF2 and the dynamic AP1 network in cancer P Lopez-Bergami, E Lau, Z Ronai Nature Reviews Cancer 10 (1), 65-76, 2010 | 388 | 2010 |
| Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation S Mujtaba, Y He, L Zeng, S Yan, O Plotnikova, R Sanchez, NJ Zeleznik-Le, ... Molecular cell 13 (2), 251-263, 2004 | 387 | 2004 |
| ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation H Habelhah, K Shah, L Huang, A Ostareck-Lederer, AL Burlingame, ... Nature cell biology 3 (3), 325-330, 2001 | 380 | 2001 |
| SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53 T Buschmann, SY Fuchs, CG Lee, ZQ Pan, Z Ronai Cell 101 (7), 753-762, 2000 | 378 | 2000 |
Eric LauMoffitt Cancer Center & Research InstituteVerified email at Moffitt.org
