| Linking the human gut microbiome to inflammatory cytokine production capacity M Schirmer, SP Smeekens, H Vlamakis, M Jaeger, M Oosting, ... Cell 167 (4), 1125-1136. e8, 2016 | 1331 | 2016 |
| The effect of host genetics on the gut microbiome MJ Bonder, A Kurilshikov, EF Tigchelaar, Z Mujagic, F Imhann, AV Vila, ... Nature genetics 48 (11), 1407-1412, 2016 | 936 | 2016 |
| STAT1 Mutations in Autosomal Dominant Chronic Mucocutaneous Candidiasis FL van de Veerdonk, TS Plantinga, A Hoischen, SP Smeekens, ... New England Journal of Medicine 365 (1), 54-61, 2011 | 785 | 2011 |
| Host and environmental factors influencing individual human cytokine responses R Ter Horst, M Jaeger, SP Smeekens, M Oosting, MA Swertz, Y Li, ... Cell 167 (4), 1111-1124. e13, 2016 | 566 | 2016 |
| Gut microbiome in ADHD and its relation to neural reward anticipation E Aarts, THA Ederveen, J Naaijen, MP Zwiers, J Boekhorst, ... PloS one 12 (9), e0183509, 2017 | 407 | 2017 |
| A functional genomics approach to understand variation in cytokine production in humans Y Li, M Oosting, SP Smeekens, M Jaeger, R Aguirre-Gamboa, KTT Le, ... Cell 167 (4), 1099-1110. e14, 2016 | 371 | 2016 |
| IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans A de Luca, SP Smeekens, A Casagrande, R Iannitti, KL Conway, ... Proceedings of the National Academy of Sciences 111 (9), 3526-3531, 2014 | 338 | 2014 |
| Reactive oxygen species–independent activation of the IL-1β inflammasome in cells from patients with chronic granulomatous disease FL van de Veerdonk, SP Smeekens, LAB Joosten, BJ Kullberg, ... Proceedings of the National Academy of Sciences 107 (7), 3030-3033, 2010 | 280 | 2010 |
| The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans SC Cheng, FL van de Veerdonk, M Lenardon, M Stoffels, T Plantinga, ... Journal of leukocyte biology 90 (2), 357-366, 2011 | 233 | 2011 |
| Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans SP Smeekens, A Ng, V Kumar, MD Johnson, TS Plantinga, C Van Diemen, ... Nature communications 4 (1), 1342, 2013 | 224 | 2013 |
| Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi Y Li, M Oosting, P Deelen, I Ricaño-Ponce, S Smeekens, M Jaeger, ... Nature medicine 22 (8), 952-960, 2016 | 219 | 2016 |
| Differential effects of environmental and genetic factors on T and B cell immune traits R Aguirre-Gamboa, I Joosten, PCM Urbano, RG van der Molen, ... Cell reports 17 (9), 2474-2487, 2016 | 217 | 2016 |
| Genetic susceptibility to Candida infections SP Smeekens, FL van de Veerdonk, BJ Kullberg, MG Netea EMBO molecular medicine 5 (6), 805-813, 2013 | 169 | 2013 |
| The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis FL van de Veerdonk, LAB Joosten, PJ Shaw, SP Smeekens, ... European journal of immunology 41 (8), 2260-2268, 2011 | 169 | 2011 |
| Sex-specific regulation of inflammation and metabolic syndrome in obesity R Ter Horst, ICL van den Munckhof, K Schraa, R Aguirre-Gamboa, ... Arteriosclerosis, thrombosis, and vascular biology 40 (7), 1787-1800, 2020 | 152 | 2020 |
| Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses OB Bakker, R Aguirre-Gamboa, S Sanna, M Oosting, SP Smeekens, ... Nature immunology 19 (7), 776-786, 2018 | 148 | 2018 |
| Gain‐of‐function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC) J Zheng, FL van de Veerdonk, KL Crossland, SP Smeekens, CM Chan, ... European journal of immunology 45 (10), 2834-2846, 2015 | 143 | 2015 |
| STAT1 hyperphosphorylation and defective IL12R/IL23R signaling underlie defective immunity in autosomal dominant chronic mucocutaneous candidiasis SP Smeekens, TS Plantinga, FL van de Veerdonk, B Heinhuis, ... PloS one 6 (12), e29248, 2011 | 139 | 2011 |
| Joosten LAB, Zhernakova A, Huttenhower C, Wijmenga C, Netea MG, Xavier RJ. Linking the human gut microbiome to inflammatory cytokine production capacity M Schirmer, SP Smeekens, H Vlamakis, M Jaeger, M Oosting, ... Cell 167 (4), 1125-1136, 2016 | 124 | 2016 |
| Skin microbiome imbalance in patients with STAT1/STAT3 defects impairs innate host defense responses SP Smeekens, C Huttenhower, A Riza, FL Van De Veerdonk, ... Journal of innate immunity 6 (3), 253-262, 2014 | 122 | 2014 |
Cisca Wijmenga, PhDERC advanced investigator; Professor of Human Genetics, Dept Genetics (MGE), UMCG, Groningen, theVerified email at umcg.nl
