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Shih-Chin James Cheng
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mTOR-and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity
SC Cheng, J Quintin, RA Cramer, KM Shepardson, S Saeed, V Kumar, ...
science 345 (6204), 1250684, 2014
23332014
Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity
S Saeed, J Quintin, HHD Kerstens, NA Rao, A Aghajanirefah, F Matarese, ...
science 345 (6204), 1251086, 2014
18252014
Glutaminolysis and fumarate accumulation integrate immunometabolic and epigenetic programs in trained immunity
RJW Arts, B Novakovic, R Ter Horst, A Carvalho, S Bekkering, ...
Cell metabolism 24 (6), 807-819, 2016
9132016
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis
SC Cheng, BP Scicluna, RJW Arts, MS Gresnigt, E Lachmandas, ...
Nature immunology 17 (4), 406-413, 2016
6462016
CLEC5A is critical for dengue-virus-induced lethal disease
ST Chen, YL Lin, MT Huang, MF Wu, SC Cheng, HY Lei, CK Lee, ...
Nature 453 (7195), 672-676, 2008
5042008
The macrophage mannose receptor induces IL-17 in response to Candida albicans
FL van de Veerdonk, RJ Marijnissen, BJ Kullberg, HJPM Koenen, ...
Cell host & microbe 5 (4), 329-340, 2009
4412009
Human TLR10 is an anti-inflammatory pattern-recognition receptor
M Oosting, SC Cheng, JM Bolscher, R Vestering-Stenger, TS Plantinga, ...
Proceedings of the National Academy of Sciences 111 (42), E4478-E4484, 2014
3682014
Interplay between Candida albicans and the mammalian innate host defense
SC Cheng, LAB Joosten, BJ Kullberg, MG Netea
Infection and immunity 80 (4), 1304-1313, 2012
3592012
Innate immune memory: towards a better understanding of host defense mechanisms
J Quintin, SC Cheng, JWM van Der Meer, MG Netea
Current opinion in immunology 29, 1-7, 2014
3292014
The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans
SC Cheng, FL van de Veerdonk, M Lenardon, M Stoffels, T Plantinga, ...
Journal of leukocyte biology 90 (2), 357-366, 2011
2332011
Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans
SP Smeekens, A Ng, V Kumar, MD Johnson, TS Plantinga, C Van Diemen, ...
Nature communications 4 (1), 1342, 2013
2242013
Growth of Candida albicans cells on the physiologically relevant carbon source lactate affects their recognition and phagocytosis by immune cells
IV Ene, SC Cheng, MG Netea, AJP Brown
Infection and immunity 81 (1), 238-248, 2013
1712013
Anti‐Aspergillus human host defence relies on type 1 T helper (Th1), rather than type 17 T helper (Th17), cellular immunity
LYA Chai, F Van De Veerdonk, RJ Marijnissen, SC Cheng, AL Khoo, ...
Immunology 130 (1), 46-54, 2010
1642010
Novel structural features in Candida albicans hyphal glucan provide a basis for differential innate immune recognition of hyphae versus yeast
DW Lowman, RR Greene, DW Bearden, MD Kruppa, M Pottier, ...
Journal of Biological Chemistry 289 (6), 3432-3443, 2014
1622014
Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence against Mycobacterium tuberculosis in human and murine cells
E Lachmandas, M Beigier‐Bompadre, SC Cheng, V Kumar, ...
European journal of immunology 46 (11), 2574-2586, 2016
1602016
Fungal chitin induces trained immunity in human monocytes during cross-talk of the host with Saccharomyces cerevisiae
L Rizzetto, DC Ifrim, S Moretti, N Tocci, SC Cheng, J Quintin, G Renga, ...
Journal of Biological Chemistry 291 (15), 7961-7972, 2016
1492016
Ubiquitin ligase TRIM62 regulates CARD9-mediated anti-fungal immunity and intestinal inflammation
Z Cao, KL Conway, RJ Heath, JS Rush, ES Leshchiner, ZG Ramirez-Ortiz, ...
Immunity 43 (4), 715-726, 2015
1482015
The interplay between central metabolism and innate immune responses
SC Cheng, LAB Joosten, MG Netea
Cytokine & growth factor reviews 25 (6), 707-713, 2014
1192014
Candida albicans dampens host defense by downregulating IL-17 production
SC Cheng, F van de Veerdonk, S Smeekens, LAB Joosten, ...
The Journal of Immunology 185 (4), 2450-2457, 2010
1172010
The glycolysis/HIF-1α axis defines the inflammatory role of IL-4-primed macrophages
B Dang, Q Gao, L Zhang, J Zhang, H Cai, Y Zhu, Q Zhong, J Liu, Y Niu, ...
Cell Reports 42 (5), 2023
1162023
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