| Systematic identification of trans eQTLs as putative drivers of known disease associations HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ... Nature genetics 45 (10), 1238-1243, 2013 | 2043 | 2013 |
| Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis MA Sanjuan, CP Dillon, SWG Tait, S Moshiach, F Dorsey, S Connell, ... Nature 450 (7173), 1253-1257, 2007 | 1600 | 2007 |
| Inflammation-associated cancer: NF-κB is the lynchpin Q Li, S Withoff, IM Verma Trends in immunology 26 (6), 318-325, 2005 | 395 | 2005 |
| A functional genomics approach to understand variation in cytokine production in humans Y Li, M Oosting, SP Smeekens, M Jaeger, R Aguirre-Gamboa, KTT Le, ... Cell 167 (4), 1099-1110. e14, 2016 | 371 | 2016 |
| Human disease-associated genetic variation impacts large intergenic non-coding RNA expression V Kumar, HJ Westra, J Karjalainen, DV Zhernakova, T Esko, B Hrdlickova, ... PLoS genetics 9 (1), e1003201, 2013 | 361 | 2013 |
| Genetic variation in the non-coding genome: Involvement of micro-RNAs and long non-coding RNAs in disease B Hrdlickova, RC de Almeida, Z Borek, S Withoff Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (10 …, 2014 | 328 | 2014 |
| Differential effects of environmental and genetic factors on T and B cell immune traits R Aguirre-Gamboa, I Joosten, PCM Urbano, RG van der Molen, ... Cell reports 17 (9), 2474-2487, 2016 | 217 | 2016 |
| From genome-wide association studies to disease mechanisms: celiac disease as a model for autoimmune diseases V Kumar, C Wijmenga, S Withoff Seminars in Immunopathology, 1-14, 2012 | 216 | 2012 |
| Clinical implications of shared genetics and pathogenesis in autoimmune diseases A Zhernakova, S Withoff, C Wijmenga Nature Reviews Endocrinology 9 (11), 646-659, 2013 | 206 | 2013 |
| Intestinal barrier function in gluten-related disorders D Cardoso-Silva, D Delbue, A Itzlinger, R Moerkens, S Withoff, F Branchi, ... Nutrients 11 (10), 2325, 2019 | 174 | 2019 |
| NF-κB and the regulation of hematopoiesis V Bottero, S Withoff, IM Verma Cell Death & Differentiation 13 (5), 785-797, 2006 | 154 | 2006 |
| Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses OB Bakker, R Aguirre-Gamboa, S Sanna, M Oosting, SP Smeekens, ... Nature immunology 19 (7), 776-786, 2018 | 148 | 2018 |
| Understanding celiac disease by genomics S Withoff, Y Li, I Jonkers, C Wijmenga Trends in Genetics 32 (5), 295-308, 2016 | 126 | 2016 |
| Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell-type specificity B Hrdlickova, V Kumar, K Kanduri, DV Zhernakova, S Tripathi, ... Genome medicine 6 (10), 88, 2014 | 126 | 2014 |
| A liver‐specific long noncoding RNA with a role in cell viability is elevated in human nonalcoholic steatohepatitis B Atanasovska, SS Rensen, MR van der Sijde, G Marsman, V Kumar, ... Hepatology 66 (3), 794-808, 2017 | 110 | 2017 |
| Fas receptor clustering and involvement of the death receptor pathway in rituximab-mediated apoptosis with concomitant sensitization of lymphoma B cells to fas-induced apoptosis AJ Stel, B Ten Cate, S Jacobs, JW Kok, DCJ Spierings, M Dondorff, ... The Journal of Immunology 178 (4), 2287-2295, 2007 | 108 | 2007 |
| A large variety of clinical features and concomitant disorders in celiac disease–a cohort study in the Netherlands M Spijkerman, IL Tan, JJ Kolkman, S Withoff, C Wijmenga, ... Digestive and Liver Disease 48 (5), 499-505, 2016 | 105 | 2016 |
| Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidaemia V Kumar, SC Cheng, MD Johnson, SP Smeekens, A Wojtowicz, ... Nature communications 5 (1), 4675, 2014 | 105 | 2014 |
| Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs I Ricaño-Ponce, DV Zhernakova, P Deelen, O Luo, X Li, A Isaacs, ... Journal of autoimmunity 68, 62-74, 2016 | 100 | 2016 |
| Systematic annotation of celiac disease loci refines pathological pathways and suggests a genetic explanation for increased interferon-gamma levels V Kumar, J Gutierrez-Achury, K Kanduri, R Almeida, B Hrdlickova, ... Human molecular genetics 24 (2), 397-409, 2015 | 99 | 2015 |
Cisca Wijmenga, PhDERC advanced investigator; Professor of Human Genetics, Dept Genetics (MGE), UMCG, Groningen, theVerified email at umcg.nl
