| ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules A Leaver-Fay, M Tyka, SM Lewis, OF Lange, J Thompson, R Jacak, ... Methods in enzymology 487, 545-574, 2011 | 2308 | 2011 |
| RosettaScripts: a scripting language interface to the Rosetta macromolecular modeling suite SJ Fleishman, A Leaver-Fay, JE Corn, EM Strauch, SD Khare, N Koga, ... PloS one 6 (6), e20161, 2011 | 761 | 2011 |
| Computational design of proteins targeting the conserved stem region of influenza hemagglutinin SJ Fleishman, TA Whitehead, DC Ekiert, C Dreyfus, JE Corn, EM Strauch, ... Science 332 (6031), 816-821, 2011 | 752 | 2011 |
| High-resolution mapping of protein sequence-function relationships DM Fowler, CL Araya, SJ Fleishman, EH Kellogg, JJ Stephany, D Baker, ... Nature methods 7 (9), 741-746, 2010 | 669 | 2010 |
| Automated structure-and sequence-based design of proteins for high bacterial expression and stability A Goldenzweig, M Goldsmith, SE Hill, O Gertman, P Laurino, Y Ashani, ... Molecular cell 63 (2), 337-346, 2016 | 649 | 2016 |
| Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing TA Whitehead, A Chevalier, Y Song, C Dreyfus, SJ Fleishman, ... Nature biotechnology 30 (6), 543-548, 2012 | 485 | 2012 |
| Comment on" Network motifs: simple building blocks of complex networks" and" Superfamilies of evolved and designed networks" Y Artzy-Randrup, SJ Fleishman, N Ben-Tal, L Stone science 305 (5687), 1107-1107, 2004 | 354 | 2004 |
| A putative molecular-activation switch in the transmembrane domain of erbB2 SJ Fleishman, J Schlessinger, N Ben-Tal Proceedings of the National Academy of Sciences 99 (25), 15937-15940, 2002 | 342 | 2002 |
| Principles of protein stability and their application in computational design A Goldenzweig, SJ Fleishman Annual review of biochemistry 87 (1), 105-129, 2018 | 320 | 2018 |
| Dominant mutations in the autoimmune regulator AIRE are associated with common organ-specific autoimmune diseases BE Oftedal, A Hellesen, MM Erichsen, E Bratland, A Vardi, J Perheentupa, ... Immunity 42 (6), 1185-1196, 2015 | 303 | 2015 |
| Automated design of efficient and functionally diverse enzyme repertoires O Khersonsky, R Lipsh, Z Avizemer, Y Ashani, M Goldsmith, H Leader, ... Molecular cell 72 (1), 178-186. e5, 2018 | 300 | 2018 |
| Principles for computational design of binding antibodies D Baran, MG Pszolla, GD Lapidoth, C Norn, O Dym, T Unger, S Albeck, ... Proceedings of the National Academy of Sciences 114 (41), 10900-10905, 2017 | 176 | 2017 |
| Design and in vitro realization of carbon-conserving photorespiration DL Trudeau, C Edlich-Muth, J Zarzycki, M Scheffen, M Goldsmith, ... Proceedings of the National Academy of Sciences 115 (49), E11455-E11464, 2018 | 173 | 2018 |
| Community-wide assessment of protein-interface modeling suggests improvements to design methodology SJ Fleishman, TA Whitehead, EM Strauch, JE Corn, S Qin, HX Zhou, ... Journal of molecular biology 414 (2), 289-302, 2011 | 160 | 2011 |
| Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces S Warszawski, A Borenstein Katz, R Lipsh, L Khmelnitsky, G Ben Nissan, ... PLoS computational biology 15 (8), e1007207, 2019 | 158 | 2019 |
| Quasi-symmetry in the cryo-EM structure of EmrE provides the key to modeling its transmembrane domain SJ Fleishman, SE Harrington, A Enosh, D Halperin, CG Tate, N Ben-Tal Journal of molecular biology 364 (1), 54-67, 2006 | 149 | 2006 |
| Opportunities and challenges in design and optimization of protein function D Listov, CA Goverde, BE Correia, SJ Fleishman Nature Reviews Molecular Cell Biology 25 (8), 639-653, 2024 | 148 | 2024 |
| Free diffusion of steroid hormones across biomembranes: a simplex search with implicit solvent model calculations I Oren, SJ Fleishman, A Kessel, N Ben-Tal Biophysical journal 87 (2), 768-779, 2004 | 148 | 2004 |
| AbDesign: An algorithm for combinatorial backbone design guided by natural conformations and sequences GD Lapidoth, D Baran, GM Pszolla, C Norn, A Alon, MD Tyka, ... Proteins: Structure, Function, and Bioinformatics 83 (8), 1385-1406, 2015 | 141 | 2015 |
| The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction NAG Meenan, A Sharma, SJ Fleishman, CJ MacDonald, B Morel, ... Proceedings of the National Academy of Sciences 107 (22), 10080-10085, 2010 | 131 | 2010 |
David BakerUniversity of WashingtonVerified email at uw.edu
