| AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo B Faubert, G Boily, S Izreig, T Griss, B Samborska, Z Dong, F Dupuy, ... Cell metabolism 17 (1), 113-124, 2013 | 1080 | 2013 |
| mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation M Morita, SP Gravel, V Chenard, K Sikström, L Zheng, T Alain, V Gandin, ... Cell metabolism 18 (5), 698-711, 2013 | 967 | 2013 |
| Mitochondrial phosphoenolpyruvate carboxykinase regulates metabolic adaptation and enables glucose-independent tumor growth EE Vincent, A Sergushichev, T Griss, MC Gingras, B Samborska, ... Molecular cell 60 (2), 195-207, 2015 | 325 | 2015 |
| Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1α B Faubert, EE Vincent, T Griss, B Samborska, S Izreig, RU Svensson, ... Proceedings of the National Academy of Sciences 111 (7), 2554-2559, 2014 | 309 | 2014 |
| Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro AM Näär, PA Beaurang, KM Robinson, JD Oliner, D Avizonis, S Scheek, ... Genes & development 12 (19), 3020-3031, 1998 | 254 | 1998 |
| PGC-1α supports glutamine metabolism in breast cancer S McGuirk, SP Gravel, G Deblois, DJ Papadopoli, B Faubert, A Wegner, ... Cancer & metabolism 1 (1), 22, 2013 | 191 | 2013 |
| Are Metformin Doses Used in Murine Cancer Models Clinically Relevant? MP Navdeep S Chandel, Dania Avizonis, Colleen R Reczek, Samuel E Weinberg ... Cell Metabolism, 2016 | 185 | 2016 |
| eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma K Chan, F Robert, C Oertlin, D Kapeller-Libermann, D Avizonis, ... Nature communications 10 (1), 5151, 2019 | 124 | 2019 |
| Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome MA Wynosky-Dolfi, AG Snyder, NH Philip, PJ Doonan, MC Poffenberger, ... Journal of Experimental Medicine 211 (4), 653-668, 2014 | 116 | 2014 |
| Leveraging increased cytoplasmic nucleoside kinase activity to target mtDNA and oxidative phosphorylation in AML SU Liyanage, R Hurren, V Voisin, G Bridon, X Wang, CJ Xu, N MacLean, ... Blood, The Journal of the American Society of Hematology 129 (19), 2657-2666, 2017 | 94 | 2017 |
| Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN Y Li, MF Pazyra-Murphy, D Avizonis, M de Sá Tavares Russo, S Tang, ... Journal of Cell Biology 221 (2), e202106080, 2021 | 89 | 2021 |
| Translational and HIF-1α-dependent metabolic reprogramming underpin metabolic plasticity and responses to kinase inhibitors and biguanides L Hulea, SP Gravel, M Morita, M Cargnello, O Uchenunu, YK Im, ... Cell metabolism 28 (6), 817-832. e8, 2018 | 89 | 2018 |
| Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis D He, H Feng, B Sundberg, J Yang, J Powers, AH Christian, JE Wilkinson, ... Molecular cell 82 (16), 3045-3060. e11, 2022 | 78 | 2022 |
| PGC-1α promotes the growth of ErbB2/Neu–induced mammary tumors by regulating nutrient supply E Klimcakova, V Chénard, S McGuirk, D Germain, D Avizonis, WJ Muller, ... Cancer research 72 (6), 1538-1546, 2012 | 75 | 2012 |
| STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer SP Totten, YK Im, E Cepeda Cañedo, O Najyb, A Nguyen, S Hébert, ... Nature Communications 12 (1), 3299, 2021 | 65 | 2021 |
| The complete targeted profile of the organic acid intermediates of the citric acid cycle using a single stable isotope dilution analysis, sodium borodeuteride reduction and … O Mamer, SP Gravel, L Choiniere, V Chénard, J St-Pierre, D Avizonis Metabolomics 9 (5), 1019-1030, 2013 | 65 | 2013 |
| Glucose-dependent partitioning of arginine to the urea cycle protects β-cells from inflammation A Fu, JC Alvarez-Perez, D Avizonis, T Kin, SB Ficarro, DW Choi, ... Nature metabolism 2 (5), 432-446, 2020 | 64 | 2020 |
| LKB1 is a central regulator of tumor initiation and pro-growth metabolism in ErbB2-mediated breast cancer F Dupuy, T Griss, J Blagih, G Bridon, D Avizonis, C Ling, Z Dong, ... Cancer & metabolism 1 (1), 18, 2013 | 59 | 2013 |
| Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets A Fu, L van Rooyen, L Evans, N Armstrong, D Avizonis, T Kin, GH Bird, ... Cell reports 37 (8), 2021 | 58 | 2021 |
| Synergy between the NAMPT inhibitor GMX1777 (8) and pemetrexed in non–small cell lung cancer cells is mediated by PARP activation and enhanced NAD consumption M Chan, M Gravel, A Bramoullé, G Bridon, D Avizonis, GC Shore, ... Cancer research 74 (21), 5948-5954, 2014 | 55 | 2014 |
Russell G JonesVan Andel Research InstituteVerified email at vai.org
