| Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? W Filipowicz, SN Bhattacharyya, N Sonenberg Nature reviews genetics 9 (2), 102-114, 2008 | 6802 | 2008 |
| Upstream and downstream of mTOR N Hay, N Sonenberg Genes & development 18 (16), 1926-1945, 2004 | 5676 | 2004 |
| Regulation of translation initiation in eukaryotes: mechanisms and biological targets N Sonenberg, AG Hinnebusch Cell 136 (4), 731-745, 2009 | 4148 | 2009 |
| Regulation of mRNA translation and stability by microRNAs MR Fabian, N Sonenberg, W Filipowicz Annual review of biochemistry 79 (1), 351-379, 2010 | 3927 | 2010 |
| eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation AC Gingras, B Raught, N Sonenberg Annual review of biochemistry 68 (1), 913-963, 1999 | 2846 | 1999 |
| Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA J Pelletier, N Sonenberg Nature 334 (6180), 320-325, 1988 | 2736 | 1988 |
| Regulation of translation initiation by FRAP/mTOR AC Gingras, B Raught, N Sonenberg Genes & development 15 (7), 807-826, 2001 | 1827 | 2001 |
| Translational control in stress and apoptosis M Holcik, N Sonenberg Nature reviews Molecular cell biology 6 (4), 318-327, 2005 | 1812 | 2005 |
| Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism AC Gingras, SP Gygi, B Raught, RD Polakiewicz, RT Abraham, ... Genes & development 13 (11), 1422-1437, 1999 | 1798 | 1999 |
| Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function A Pause, GJ Belsham, AC Gingras, O Donzé, TA Lin, JC Lawrence Jr, ... Nature 371 (6500), 762-767, 1994 | 1674 | 1994 |
| Metformin is an AMP kinase–dependent growth inhibitor for breast cancer cells M Zakikhani, R Dowling, IG Fantus, N Sonenberg, M Pollak Cancer research 66 (21), 10269-10273, 2006 | 1383 | 2006 |
| Regulation of cap-dependent translation by eIF4E inhibitory proteins JD Richter, N Sonenberg Nature 433 (7025), 477-480, 2005 | 1329 | 2005 |
| XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation AL Shaffer, M Shapiro-Shelef, NN Iwakoshi, AH Lee, SB Qian, H Zhao, ... Immunity 21 (1), 81-93, 2004 | 1328 | 2004 |
| The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC MR Fabian, N Sonenberg Nature structural & molecular biology 19 (6), 586-593, 2012 | 1320 | 2012 |
| Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5'cap A Lazaris-Karatzas, KS Montine, N Sonenberg Nature 345 (6275), 544-547, 1990 | 1271 | 1990 |
| Translational control by 5′-untranslated regions of eukaryotic mRNAs AG Hinnebusch, IP Ivanov, N Sonenberg Science 352 (6292), 1413-1416, 2016 | 1261 | 2016 |
| Hierarchical phosphorylation of the translation inhibitor 4E-BP1 AC Gingras, B Raught, SP Gygi, A Niedzwiecka, M Miron, SK Burley, ... Genes & development 15 (21), 2852-2864, 2001 | 1214 | 2001 |
| Metformin inhibits mammalian target of rapamycin–dependent translation initiation in breast cancer cells RJO Dowling, M Zakikhani, IG Fantus, M Pollak, N Sonenberg Cancer research 67 (22), 10804-10812, 2007 | 1191 | 2007 |
| 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt (PKB) signaling pathway AC Gingras, SG Kennedy, MA O’Leary, N Sonenberg, N Hay Genes & development 12 (4), 502-513, 1998 | 1178 | 1998 |
| Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus DF Stojdl, B Lichty, S Knowles, R Marius, H Atkins, N Sonenberg, JC Bell Nature medicine 6 (7), 821-825, 2000 | 1139 | 2000 |
anne-claude gingrasLunenfeld-Tanenbaum Research Institute; Sinai Health; University of TorontoVerified email at lunenfeld.ca
