| Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) MJA DJ Klionsky, K Abdelmohsen, A Abe Autophagy 12 (1), 2016 | 14394* | 2016 |
| Targeting the translation machinery in cancer M Bhat, N Robichaud, L Hulea, N Sonenberg, J Pelletier, I Topisirovic Nature reviews Drug discovery 14 (4), 261-278, 2015 | 983 | 2015 |
| mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation M Morita, SP Gravel, V Chenard, K Sikström, L Zheng, T Alain, V Gandin, ... Cell metabolism 18 (5), 698-711, 2013 | 967 | 2013 |
| mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs RJO Dowling, I Topisirovic, T Alain, M Bidinosti, BD Fonseca, ... Science 328 (5982), 1172-1176, 2010 | 886 | 2010 |
| mTOR coordinates protein synthesis, mitochondrial activity and proliferation M Morita, SP Gravel, L Hulea, O Larsson, M Pollak, J St-Pierre, ... Cell cycle 14 (4), 473-480, 2015 | 619 | 2015 |
| Dissecting the role of mTOR: lessons from mTOR inhibitors RJO Dowling, I Topisirovic, BD Fonseca, N Sonenberg Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (3), 433-439, 2010 | 608 | 2010 |
| Cap and cap‐binding proteins in the control of gene expression I Topisirovic, YV Svitkin, N Sonenberg, AJ Shatkin Wiley Interdisciplinary Reviews: RNA 2 (2), 277-298, 2011 | 529 | 2011 |
| mTOR as a central regulator of lifespan and aging D Papadopoli, K Boulay, L Kazak, M Pollak, FA Mallette, I Topisirovic, ... F1000Research 8, F1000 Faculty Rev-998, 2019 | 508 | 2019 |
| eIF4E is a central node of an RNA regulon that governs cellular proliferation B Culjkovic, I Topisirovic, L Skrabanek, M Ruiz-Gutierrez, KLB Borden The Journal of cell biology 175 (3), 415-426, 2006 | 390 | 2006 |
| mTOR controls mitochondrial dynamics and cell survival via MTFP1 M Morita, J Prudent, K Basu, V Goyon, S Katsumura, L Hulea, D Pearl, ... Molecular cell 67 (6), 922-935. e5, 2017 | 388 | 2017 |
| Signaling pathways involved in the regulation of mRNA translation PP Roux, I Topisirovic Molecular and cellular biology 38 (12), e00070-18, 2018 | 374 | 2018 |
| Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap A Kentsis, I Topisirovic, B Culjkovic, L Shao, KLB Borden Proceedings of the National Academy of Sciences 101 (52), 18105-18110, 2004 | 370 | 2004 |
| Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities I Topisirovic, M Ruiz-Gutierrez, KLB Borden Cancer research 64 (23), 8639-8642, 2004 | 341 | 2004 |
| Translational control of immune responses: from transcripts to translatomes CA Piccirillo, E Bjur, I Topisirovic, N Sonenberg, O Larsson Nature immunology 15 (6), 503-511, 2014 | 299 | 2014 |
| Regulation of mRNA translation by signaling pathways PP Roux, I Topisirovic Cold Spring Harbor perspectives in biology 4 (11), a012252, 2012 | 284 | 2012 |
| eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3′ UTR B Culjkovic, I Topisirovic, L Skrabanek, M Ruiz-Gutierrez, KLB Borden The Journal of cell biology 169 (2), 245-256, 2005 | 273 | 2005 |
| Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport impedes hematopoietic differentiation and contributes to leukemogenesis I Topisirovic, ML Guzman, MJ McConnell, JD Licht, B Culjkovic, ... Molecular and cellular biology 23 (24), 8992-9002, 2003 | 269 | 2003 |
| nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs V Gandin, L Masvidal, L Hulea, SP Gravel, M Cargnello, S McLaughlan, ... Genome research 26 (5), 636-648, 2016 | 264 | 2016 |
| Polysome fractionation and analysis of mammalian translatomes on a genome-wide scale V Gandin, K Sikström, T Alain, M Morita, S McLaughlan, O Larsson, ... Journal of visualized experiments: JoVE, 51455, 2014 | 258 | 2014 |
| Distinct perturbation of the translatome by the antidiabetic drug metformin O Larsson, M Morita, I Topisirovic, T Alain, MJ Blouin, M Pollak, ... Proceedings of the National Academy of Sciences 109 (23), 8977-8982, 2012 | 248 | 2012 |
Nahum SonenbergGilman Cheney Professor in BiochemistryVerified email at mcgill.ca
