| Nedd8 on cullin: building an expressway to protein destruction ZQ Pan, A Kentsis, DC Dias, K Yamoah, K Wu Oncogene 23 (11), 1985-1997, 2004 | 530 | 2004 |
| DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia DC Johnson, CY Taabazuing, MC Okondo, AJ Chui, SD Rao, FC Brown, ... Nature medicine 24 (8), 1151-1156, 2018 | 371 | 2018 |
| Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap A Kentsis, I Topisirovic, B Culjkovic, L Shao, KLB Borden Proceedings of the National Academy of Sciences 101 (52), 18105-18110, 2004 | 370 | 2004 |
| PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA N Cohen, M Sharma, A Kentsis, JM Perez, S Strudwick, KLB Borden The EMBO journal, 2001 | 271 | 2001 |
| Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia A Gutierrez, L Pan, RWJ Groen, F Baleydier, A Kentsis, J Marineau, ... The Journal of clinical investigation 124 (2), 644-655, 2014 | 259 | 2014 |
| The Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity MV Poyurovsky, C Priest, A Kentsis, KLB Borden, ZQ Pan, N Pavletich, ... The EMBO journal 26 (1), 90, 2006 | 248 | 2006 |
| KPT‐330 inhibitor of CRM 1 (XPO 1)‐mediated nuclear export has selective anti‐leukaemic activity in preclinical models of T‐cell acute lymphoblastic leukaemia and acute myeloid … J Etchin, T Sanda, MR Mansour, A Kentsis, J Montero, BT Le, AL Christie, ... British journal of haematology 161 (1), 117-127, 2013 | 233 | 2013 |
| Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells J Etchin, Q Sun, A Kentsis, A Farmer, ZC Zhang, T Sanda, MR Mansour, ... Leukemia 27 (1), 66-74, 2013 | 229 | 2013 |
| Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia A Kentsis, C Reed, KL Rice, T Sanda, SJ Rodig, E Tholouli, A Christie, ... Nature medicine 18 (7), 1118-1122, 2012 | 226 | 2012 |
| The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia A Gutierrez, A Kentsis, T Sanda, L Holmfeldt, SC Chen, J Zhang, ... Blood, The Journal of the American Society of Hematology 118 (15), 4169-4173, 2011 | 221 | 2011 |
| Mechanisms of androgen induction of sebocyte differentiation RL Rosenfield, D Deplewski, A Kentsis, N Ciletti Dermatology 196 (1), 43-46, 1998 | 214 | 1998 |
| Trifluoroethanol promotes helix formation by destabilizing backbone exposure: desolvation rather than native hydrogen bonding defines the kinetic pathway of dimeric coiled coil … A Kentsis, TR Sosnick Biochemistry 37 (41), 14613-14622, 1998 | 199 | 1998 |
| Rat preputial sebocyte differentiation involves peroxisome proliferator-activated receptors RL Rosenfield, A Kentsis, D Deplewski, N Ciletti Journal of Investigative Dermatology 112 (2), 226-232, 1999 | 195 | 1999 |
| The RING domains of the promyelocytic leukemia protein PML and the arenaviral protein Z repress translation by directly inhibiting translation initiation factor eIF4E A Kentsis, EC Dwyer, JM Perez, M Sharma, A Chen, ZQ Pan, KLB Borden Journal of molecular biology 312 (4), 609-623, 2001 | 193 | 2001 |
| Urine proteomics for profiling of human disease using high accuracy mass spectrometry A Kentsis, F Monigatti, K Dorff, F Campagne, R Bachur, H Steen PROTEOMICS–Clinical Applications 3 (9), 1052-1061, 2009 | 163 | 2009 |
| Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors EM Fiala, G Jayakumaran, A Mauguen, JA Kennedy, N Bouvier, Y Kemel, ... Nature cancer 2 (3), 357-365, 2021 | 160 | 2021 |
| The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML EB Heikamp, JA Henrich, F Perner, EM Wong, C Hatton, Y Wen, ... Blood, The Journal of the American Society of Hematology 139 (6), 894-906, 2022 | 157 | 2022 |
| Advancing urinary protein biomarker discovery by data-independent acquisition on a quadrupole-orbitrap mass spectrometer J Muntel, Y Xuan, ST Berger, L Reiter, R Bachur, A Kentsis, H Steen Journal of proteome research 14 (11), 4752-4762, 2015 | 157 | 2015 |
| Impaired cell fate through gain-of-function mutations in a chromatin reader L Wan, S Chong, F Xuan, A Liang, X Cui, L Gates, TS Carroll, Y Li, L Feng, ... Nature 577 (7788), 121-126, 2020 | 146 | 2020 |
| Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia NA McNeer, J Philip, H Geiger, RE Ries, VP Lavallee, M Walsh, M Shah, ... Leukemia 33 (8), 1934-1943, 2019 | 146 | 2019 |
Hanno SteenProfessor of Pathology, Harvard Medical SchoolVerified email at childrens.harvard.edu
