| Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia AP Weng, AA Ferrando, W Lee, JP Morris IV, LB Silverman, ... Science 306 (5694), 269-271, 2004 | 3575 | 2004 |
| Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma SW Morris, MN Kirstein, MB Valentine, KG Dittmer, DN Shapiro, ... Science 263 (5151), 1281-1284, 1994 | 2893 | 1994 |
| Acute lymphoblastic leukaemia CH Pui, LL Robison, AT Look The Lancet 371 (9617), 1030-1043, 2008 | 2414 | 2008 |
| The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1 CJ Sherr, CW Rettenmier, R Sacca, MF Roussel, AT Look, ER Stanley Cell 41 (3), 665-676, 1985 | 1905 | 1985 |
| A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish P Niethammer, C Grabher, AT Look, TJ Mitchison Nature 459 (7249), 996-999, 2009 | 1885 | 2009 |
| Oncogenic transcription factors in the human acute leukemias AT Look Science 278 (5340), 1059-1064, 1997 | 1578 | 1997 |
| Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia AA Ferrando, DS Neuberg, J Staunton, ML Loh, C Huard, SC Raimondi, ... Cancer cell 1 (1), 75-87, 2002 | 1382 | 2002 |
| Human aminopeptidase N is a receptor for human coronavirus 229E CL Yeager, RA Ashmun, RK Williams, CB Cardellichio, LH Shapiro, ... Nature 357 (6377), 420-422, 1992 | 1248 | 1992 |
| NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth T Palomero, WK Lim, DT Odom, ML Sulis, PJ Real, A Margolin, ... Proceedings of the National Academy of Sciences 103 (48), 18261-18266, 2006 | 1118 | 2006 |
| Activating mutations in ALK provide a therapeutic target in neuroblastoma RE George, T Sanda, M Hanna, S Fröhling, WL Ii, J Zhang, Y Ahn, ... Nature 455 (7215), 975-978, 2008 | 1086 | 2008 |
| Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN T Teitz, T Wei, MB Valentine, EF Vanin, J Grenet, VA Valentine, FG Behm, ... Nature medicine 6 (5), 529-535, 2000 | 1024 | 2000 |
| An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element MR Mansour, BJ Abraham, L Anders, A Berezovskaya, A Gutierrez, ... Science 346 (6215), 1373-1377, 2014 | 977 | 2014 |
| FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors J O'Neil, J Grim, P Strack, S Rao, D Tibbitts, C Winter, J Hardwick, ... The Journal of experimental medicine 204 (8), 1813-1824, 2007 | 842 | 2007 |
| BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma EE Patton, HR Widlund, JL Kutok, KR Kopani, JF Amatruda, RD Murphey, ... Current Biology 15 (3), 249-254, 2005 | 821 | 2005 |
| Chromosome 1p and 11q deletions and outcome in neuroblastoma EF Attiyeh, WB London, YP Mossé, Q Wang, C Winter, D Khazi, ... New England Journal of Medicine 353 (21), 2243-2253, 2005 | 803 | 2005 |
| The use of zebrafish to understand immunity NS Trede, DM Langenau, D Traver, AT Look, LI Zon Immunity 20 (4), 367-379, 2004 | 797 | 2004 |
| Identification of breakpoints in t (8; 21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt P Erickson, J Gao, KS Chang, T Look, E Whisenant, S Raimondi, ... | 783 | 1992 |
| Evidence for an age cutoff greater than 365 days for neuroblastoma risk group stratification in the Children's Oncology Group WB London, RP Castleberry, KK Matthay, AT Look, RC Seeger, ... Journal of clinical oncology 23 (27), 6459-6465, 2005 | 770 | 2005 |
| Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study. AT Look, FA Hayes, JJ Shuster, EC Douglass, RP Castleberry, ... Journal of Clinical Oncology 9 (4), 581-591, 1991 | 762 | 1991 |
| tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors S Berghmans, RD Murphey, E Wienholds, D Neuberg, JL Kutok, ... Proceedings of the National Academy of Sciences 102 (2), 407-412, 2005 | 741 | 2005 |
Donna NeubergDana-Farber Cancer InstituteVerified email at jimmy.harvard.edu
