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Rob Christiaan van Wijk
Rob Christiaan van Wijk
Assistant professor and principal investigator Translational Immuno-Pharmacology, Leiden University
Verified email at lacdr.leidenuniv.nl - Homepage
Title
Cited by
Cited by
Year
Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double-blind, randomised, controlled, phase 3 trial
CM Upton, RC van Wijk, L Mockeliunas, USH Simonsson, K McHarry, ...
EClinicalMedicine 48, 101414, 2022
882022
Pharmacokinetic Modeling of Paracetamol Uptake and Clearance in Zebrafish Larvae: Expanding the Allometric Scale in Vertebrates with Five Orders of Magnitude
V Kantae, EHJ Krekels, A Ordas, O González, RC van Wijk, AC Harms, ...
Zebrafish 13 (6), 504-510, 2016
772016
Systems pharmacology of hepatic metabolism in zebrafish larvae
RC van Wijk, EHJ Krekels, T Hankemeier, HP Spaink, PH van der Graaf
Drug Discovery Today: Disease Models 22, 27-34, 2016
632016
Mechanistic and Quantitative Understanding of Pharmacokinetics in Zebrafish Larvae through Nanoscale Blood Sampling and Metabolite Modeling of Paracetamol
RC Van Wijk, EHJ Krekels, V Kantae, A Ordas, T Kreling, AC Harms, ...
Journal of Pharmacology and Experimental Therapeutics 371 (1), 15-24, 2019
432019
Early bactericidal activity of meropenem plus clavulanate (with or without rifampin) for tuberculosis: the COMRADE randomized, phase 2A clinical trial
V De Jager, N Gupte, S Nunes, GL Barnes, RC van Wijk, J Mostert, ...
American Journal of Respiratory and Critical Care Medicine 205 (10), 1228-1235, 2022
402022
Impact of post-hatching maturation on the pharmacokinetics of paracetamol in zebrafish larvae
RC van Wijk, EHJ Krekels, V Kantae, AC Harms, T Hankemeier, ...
Scientific Reports 9 (1), 2149, 2019
392019
Integration of PKPD relationships into benefit–risk analysis
F Bellanti, RC van Wijk, M Danhof, O Della Pasqua
British journal of clinical pharmacology 80 (5), 979-991, 2015
282015
Finding the right hazard function for time‐to‐event modeling: A tutorial and Shiny application
RC Van Wijk, USH Simonsson
CPT: Pharmacometrics & Systems Pharmacology 11 (8), 991-1001, 2022
242022
Model-Informed Drug Discovery and Development Strategy for the Rapid Development of Anti-Tuberculosis Drug Combinations
RC van Wijk, R Ayoun Alsoud, H Lennernäs, USH Simonsson
Applied Sciences 10 (7), 2376, 2020
202020
Anti‐tuberculosis effect of isoniazid scales accurately from zebrafish to humans
RC van Wijk, W Hu, SM Dijkema, DJ van den Berg, J Liu, R Bahi, ...
British Journal of Pharmacology 177 (24), 5518-5533, 2020
192020
Outside‐In Systems Pharmacology Combines Innovative Computational Methods With High‐Throughput Whole Vertebrate Studies
P Schulthess, RC van Wijk, EHJ Krekels, JWT Yates, HP Spaink, ...
CPT: pharmacometrics & systems pharmacology 7 (5), 285-287, 2018
182018
Pharmacokinetic analysis across studies to drive knowledge‐integration: A tutorial on individual patient data meta‐analysis (IPDMA)
RC van Wijk, MZ Imperial, RM Savic, BP Solans
CPT: Pharmacometrics & Systems Pharmacology 12 (9), 1187-1200, 2023
142023
Translational predictions of phase 2a first-in-patient efficacy studies for antituberculosis drugs
JP Ernest, JJN Goh, N Strydom, Q Wang, RC van Wijk, N Zhang, ...
European Respiratory Journal 62 (2), 2023
142023
Development of a population pharmacokinetic model to predict brain distribution and dopamine D2 receptor occupancy of raclopride in non-anesthetized rat
YC Wong, T Ilkova, RC van Wijk, R Hartman, ECM de Lange
European Journal of Pharmaceutical Sciences 111, 514-525, 2018
92018
Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development
L Mockeliunas, A Faraj, RC Van Wijk, CM Upton, G van den Hoogen, ...
Frontiers in Pharmacology 14, 1150243, 2023
72023
Quantification of Natural Growth of Two Strains of Mycobacterium Marinum for Translational Antituberculosis Drug Development
RC Van Wijk, AM van der Sar, EHJ Krekels, T Verboom, HP Spaink, ...
Clinical and translational Science 13 (6), 1060-1064, 2020
72020
Model‐informed pediatric dose selection of marzeptacog alfa (activated): An exposure matching strategy
A Faraj, RC Van Wijk, L Neuman, S Desai, GE Blouse, T Knudsen, ...
CPT: Pharmacometrics & Systems Pharmacology 12 (7), 977-987, 2023
62023
Seasonal influence on respiratory tract infection severity including COVID‐19 quantified through Markov Chain modeling
RC Van Wijk, L Mockeliunas, CM Upton, J Peter, AH Diacon, ...
CPT: Pharmacometrics & Systems Pharmacology 12 (9), 1250-1261, 2023
52023
Implementing best practices on data generation and reporting of Mycobacterium tuberculosis in vitro assays within the ERA4TB consortium
RC van Wijk, A Lucía, PK Sudhakar, L Sonnenkalb, C Gaudin, ...
Iscience 26 (4), 2023
42023
Risk Factors for COVID-19 and Respiratory Tract Infections during the Coronavirus Pandemic
L Mockeliunas, RC van Wijk, CM Upton, J Peter, AH Diacon, ...
Vaccines 12 (3), 329, 2024
32024
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Articles 1–20