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ZA9811217B - 7-[3-[4(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl]propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and allergy. - Google Patents

7-[3-[4(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl]propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and allergy.

Info

Publication number
ZA9811217B
ZA9811217B ZA9811217A ZA9811217A ZA9811217B ZA 9811217 B ZA9811217 B ZA 9811217B ZA 9811217 A ZA9811217 A ZA 9811217A ZA 9811217 A ZA9811217 A ZA 9811217A ZA 9811217 B ZA9811217 B ZA 9811217B
Authority
ZA
South Africa
Prior art keywords
fluorobenzo
chromen
isoxazol
psychosis
schizophrenia
Prior art date
Application number
ZA9811217A
Other languages
English (en)
Inventor
Rafael Foguet
Jordi Bolos
Aurelio Sacristan
Josep M Castello
Jose A Ortiz
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of ZA9811217B publication Critical patent/ZA9811217B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA9811217A 1997-12-30 1998-12-08 7-[3-[4(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl]propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and allergy. ZA9811217B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES009702718A ES2144355B1 (es) 1997-12-30 1997-12-30 Compuestos derivados del cromeno.

Publications (1)

Publication Number Publication Date
ZA9811217B true ZA9811217B (en) 1999-07-14

Family

ID=8301662

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9811217A ZA9811217B (en) 1997-12-30 1998-12-08 7-[3-[4(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl]propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and allergy.

Country Status (18)

Country Link
US (1) US6187793B1 (xx)
EP (1) EP0970076A1 (xx)
JP (1) JP2001515517A (xx)
KR (1) KR20000075840A (xx)
AR (1) AR017968A1 (xx)
AU (1) AU2514399A (xx)
BR (1) BR9807276A (xx)
CA (1) CA2282596A1 (xx)
ES (1) ES2144355B1 (xx)
IL (1) IL131572A0 (xx)
NO (1) NO994161L (xx)
NZ (1) NZ337260A (xx)
PA (1) PA8464301A1 (xx)
PL (1) PL335463A1 (xx)
RU (1) RU2179556C2 (xx)
TW (1) TW464650B (xx)
WO (1) WO1999035144A1 (xx)
ZA (1) ZA9811217B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE499355T1 (de) 2005-11-03 2011-03-15 Hoffmann La Roche Arylsulfonylchromane als 5-ht6-inhibitoren
CN102206214B (zh) * 2011-04-07 2014-03-12 华中科技大学 苯并吡喃酮类衍生物及其应用
KR20190015614A (ko) * 2011-05-18 2019-02-13 라퀄리아 파마 인코포레이티드 4-｛[4-(｛[4-(2,2,2-트리플루오로에톡시)-1,2-벤즈이속사졸-3-일]옥시｝메틸)피페리딘-1-일]메틸｝-테트라히드로-2h-피란-4-카르복실산의 다형
CN103694233B (zh) * 2013-12-10 2016-08-17 沈阳药科大学 苯并异噁唑类化合物及其应用
CN105153246B (zh) * 2015-08-05 2018-05-25 广州嘉德乐生化科技有限公司 一种蔗糖脂肪酸酯的制备方法及其乳饮料组合物
CN111320619A (zh) * 2018-12-17 2020-06-23 江苏恩华药业股份有限公司 一种类酰胺类衍生物的杂质及用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3117389A1 (de) * 1981-05-02 1982-11-18 Boehringer Mannheim Gmbh, 6800 Mannheim Benzopyranylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
US4678787A (en) * 1985-01-30 1987-07-07 Warner-Lambert Company 4H-1-benzopyran-4-ones and their sulfur containing analogs
EP0228893A3 (en) * 1985-12-20 1990-01-03 A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl group in allergy treatment
ATE126512T1 (de) * 1989-05-19 1995-09-15 Hoechst Roussel Pharma N-(aryloxyalkyl)heteroarylpiperidine und - heteroarylpiperazine, verfahren zu ihrer herstellung und ihre verwendung als medikamente.
FR2654104B1 (fr) * 1989-11-07 1992-01-03 Adir Nouveaux derives du 1,2-benzisoxazole, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5147881A (en) * 1990-11-14 1992-09-15 Pfizer Inc 4-(1,2-benzisoxazolyl)piperidine antipsychotic agents
JP3193508B2 (ja) * 1993-03-05 2001-07-30 興和株式会社 ピペリジン誘導体
ES2074966B1 (es) * 1994-02-11 1996-06-16 Vita Invest Sa Procedimiento para la obtencion de 3-(2-(4-(6-fluoro-benzo(d)isoxazol-3-il)piperidin-1-il)-etil)-2-metil-6,7,8,9-tetrahidro-4h-pirido-(1,2-a)pirimidin-4-ona.
IL112764A0 (en) * 1994-03-18 1995-05-26 Ferrer Int New chromene derivatives
IL117646A (en) * 1995-04-12 2000-06-01 Ferrer Int 7-¬3-¬4-(6-fluoro-1,2-benzisoxazole-3-YL)piperidin-1-YL¾propoxy¾3-alkyl-chromen-4-ones their preparation their uses and pharmaceutical compositions comprising them

Also Published As

Publication number Publication date
NZ337260A (en) 2000-09-29
IL131572A0 (en) 2001-01-28
NO994161L (no) 1999-10-25
ES2144355A1 (es) 2000-06-01
ES2144355B1 (es) 2001-01-01
CA2282596A1 (en) 1999-07-15
PL335463A1 (en) 2000-04-25
RU2179556C2 (ru) 2002-02-20
US6187793B1 (en) 2001-02-13
JP2001515517A (ja) 2001-09-18
TW464650B (en) 2001-11-21
PA8464301A1 (es) 2000-09-29
AR017968A1 (es) 2001-10-24
AU2514399A (en) 1999-07-26
KR20000075840A (ko) 2000-12-26
WO1999035144A1 (en) 1999-07-15
NO994161D0 (no) 1999-08-27
EP0970076A1 (en) 2000-01-12
BR9807276A (pt) 2000-05-02

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