ZA964012B - Cyclic peptide antifungal agents. - Google Patents
Cyclic peptide antifungal agents.Info
- Publication number
- ZA964012B ZA964012B ZA9604012A ZA964012A ZA964012B ZA 964012 B ZA964012 B ZA 964012B ZA 9604012 A ZA9604012 A ZA 9604012A ZA 964012 A ZA964012 A ZA 964012A ZA 964012 B ZA964012 B ZA 964012B
- Authority
- ZA
- South Africa
- Prior art keywords
- chem
- antifungal agents
- cyclic peptide
- alkyl
- peptide antifungal
- Prior art date
Links
- 108010069514 Cyclic Peptides Proteins 0.000 title 1
- 102000001189 Cyclic Peptides Human genes 0.000 title 1
- 229940121375 antifungal agent Drugs 0.000 title 1
- 239000003429 antifungal agent Substances 0.000 title 1
- 125000004642 (C1-C12) alkoxy group Chemical group 0.000 abstract 1
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 abstract 1
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002538 fungal effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 230000003071 parasitic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45170595A | 1995-05-26 | 1995-05-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA964012B true ZA964012B (en) | 1997-11-20 |
Family
ID=23793379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9604012A ZA964012B (en) | 1995-05-26 | 1996-05-20 | Cyclic peptide antifungal agents. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5629290A (xx) |
| EP (1) | EP0744406B1 (xx) |
| JP (1) | JPH11505846A (xx) |
| AT (1) | ATE223432T1 (xx) |
| AU (1) | AU5799396A (xx) |
| CA (1) | CA2220688A1 (xx) |
| DE (1) | DE69623387T2 (xx) |
| ES (1) | ES2178693T3 (xx) |
| IL (1) | IL118332A0 (xx) |
| PE (1) | PE38297A1 (xx) |
| WO (1) | WO1996037511A1 (xx) |
| ZA (1) | ZA964012B (xx) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5965525A (en) * | 1992-03-19 | 1999-10-12 | Eli Lilly And Company | Cyclic peptide antifungal agents |
| US6384013B1 (en) | 1992-03-19 | 2002-05-07 | Eli Lilly And Company | Cyclic peptide antifungal agents and process for preparation thereof |
| US6743777B1 (en) * | 1992-03-19 | 2004-06-01 | Eli Lilly And Company | Cyclic peptide antifungal agents and process for preparation thereof |
| US6323176B1 (en) | 1998-02-25 | 2001-11-27 | Eli Lilly And Company | Cyclic peptide antifungal agents |
| ES2233070T3 (es) | 1998-08-20 | 2005-06-01 | ELI LILLY & COMPANY | Sintesis de analogos peptidicos ciclicos modificados en el anillo. |
| IL143563A0 (en) | 1998-12-09 | 2002-04-21 | Lilly Co Eli | Purification of echinocandin cyclopeptide compounds |
| DE60004793T2 (de) | 1999-03-03 | 2004-07-01 | Eli Lilly And Co., Indianapolis | Echinocandin-kohlenhydrate-komplexe |
| DK1155034T3 (da) | 1999-03-03 | 2007-01-08 | Lilly Co Eli | Dannelse og anionbytning af indre krystallinske echinocandin B-ammoniumsalte |
| WO2000051564A1 (en) * | 1999-03-03 | 2000-09-08 | Eli Lilly And Company | Echinocandin pharmaceutical formulations containing micelle-forming surfactants |
| CN1345230A (zh) | 1999-03-03 | 2002-04-17 | 伊莱利利公司 | 口服ecb药物制剂和药物组合物的制备方法 |
| US6991800B2 (en) * | 2002-06-13 | 2006-01-31 | Vicuron Pharmaceuticals Inc. | Antifungal parenteral products |
| US7109519B2 (en) | 2003-07-15 | 2006-09-19 | 3M Innovative Properties Company | Bis(2-acenyl)acetylene semiconductors |
| CN116903706B (zh) * | 2023-06-13 | 2024-05-17 | 深圳市祥根生物有限公司 | 一种棘白菌素类药物及其制备方法和用途 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4320052A (en) * | 1979-12-13 | 1982-03-16 | Eli Lilly And Company | Derivatives of A-30912A nucleus |
| US4293489A (en) * | 1979-12-13 | 1981-10-06 | Eli Lilly And Company | Derivatives of A-30912A nucleus |
| US4293488A (en) * | 1979-12-13 | 1981-10-06 | Eli Lilly And Company | Derivatives of A-30912B nucleus |
| DK173802B1 (da) * | 1988-09-12 | 2001-11-05 | Merck & Co Inc | Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner |
| US5166135A (en) * | 1988-09-12 | 1992-11-24 | Merck & Company, Inc. | Method for the control of pneumocystis carinii |
| CA2037957A1 (en) * | 1990-03-12 | 1991-09-13 | Merck & Co., Inc. | N-acylated cyclohexapeptide compounds |
| GB2241956A (en) * | 1990-03-16 | 1991-09-18 | Merck & Co Inc | N-acylated cyclohexapeptide compounds |
| IL97347A0 (en) * | 1990-03-19 | 1992-05-25 | Merck & Co Inc | Lipopeptide derivatives and antimicrobial compositions containing them |
| US5330973A (en) * | 1990-03-19 | 1994-07-19 | Merck & Co., Inc. | Lipopeptide derivatives |
| US5310726A (en) * | 1990-03-19 | 1994-05-10 | Merck & Co., Inc. | Lipopeptide compounds |
| IE910892A1 (en) * | 1990-03-19 | 1991-09-25 | Merck & Co Inc | Lipopeptide compounds |
| US5386009A (en) * | 1990-03-19 | 1995-01-31 | Merck & Co. Inc. | Lipopeptide derivatives |
| US5049546A (en) * | 1990-03-19 | 1991-09-17 | Merck & Co., Inc. | Antibiotic agents |
| IL98506A (en) * | 1990-06-18 | 1996-09-12 | Fujisawa Pharmaceutical Co | Cyclic peptide antibiotics processes for the preparation thereof and pharmaceutical compositions containing them |
| US5369093A (en) * | 1991-03-15 | 1994-11-29 | Merck & Co., Inc. | Lipopeptide derivatives |
| US5233023A (en) * | 1991-07-30 | 1993-08-03 | Merck & Co., Inc. | Process for phosphate ester compounds of certain cyclohexapeptides |
| IL105048A (en) * | 1992-03-19 | 2001-06-14 | Eli Lilly And Company U S | Cyclic peptide antifungal agents and process for preparation thereof |
-
1996
- 1996-03-08 US US08/611,611 patent/US5629290A/en not_active Expired - Fee Related
- 1996-05-20 ZA ZA9604012A patent/ZA964012B/xx unknown
- 1996-05-20 IL IL11833296A patent/IL118332A0/xx unknown
- 1996-05-20 WO PCT/US1996/007251 patent/WO1996037511A1/en not_active Ceased
- 1996-05-20 AU AU57993/96A patent/AU5799396A/en not_active Abandoned
- 1996-05-20 JP JP8535784A patent/JPH11505846A/ja not_active Withdrawn
- 1996-05-20 CA CA002220688A patent/CA2220688A1/en not_active Abandoned
- 1996-05-21 EP EP96303603A patent/EP0744406B1/en not_active Expired - Lifetime
- 1996-05-21 DE DE69623387T patent/DE69623387T2/de not_active Expired - Fee Related
- 1996-05-21 AT AT96303603T patent/ATE223432T1/de not_active IP Right Cessation
- 1996-05-21 ES ES96303603T patent/ES2178693T3/es not_active Expired - Lifetime
- 1996-05-22 PE PE1996000371A patent/PE38297A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996037511A1 (en) | 1996-11-28 |
| JPH11505846A (ja) | 1999-05-25 |
| US5629290A (en) | 1997-05-13 |
| AU5799396A (en) | 1996-12-11 |
| DE69623387D1 (de) | 2002-10-10 |
| EP0744406A3 (en) | 1998-05-20 |
| IL118332A0 (en) | 1996-09-12 |
| EP0744406B1 (en) | 2002-09-04 |
| ATE223432T1 (de) | 2002-09-15 |
| PE38297A1 (es) | 1997-10-09 |
| CA2220688A1 (en) | 1996-11-28 |
| DE69623387T2 (de) | 2003-01-09 |
| EP0744406A2 (en) | 1996-11-27 |
| ES2178693T3 (es) | 2003-01-01 |
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