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ZA928011B - Transdermal administration of melatonin. - Google Patents

Transdermal administration of melatonin.

Info

Publication number
ZA928011B
ZA928011B ZA928011A ZA928011A ZA928011B ZA 928011 B ZA928011 B ZA 928011B ZA 928011 A ZA928011 A ZA 928011A ZA 928011 A ZA928011 A ZA 928011A ZA 928011 B ZA928011 B ZA 928011B
Authority
ZA
South Africa
Prior art keywords
melatonin
transdermal administration
transdermal
administration
Prior art date
Application number
ZA928011A
Other languages
English (en)
Inventor
F Eugene Yates
Lina T Taskovich
Su Il Yum
Nieves Marzan Crisologo
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of ZA928011B publication Critical patent/ZA928011B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
ZA928011A 1991-10-18 1992-10-16 Transdermal administration of melatonin. ZA928011B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77921591A 1991-10-18 1991-10-18

Publications (1)

Publication Number Publication Date
ZA928011B true ZA928011B (en) 1993-06-23

Family

ID=25115696

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA928011A ZA928011B (en) 1991-10-18 1992-10-16 Transdermal administration of melatonin.

Country Status (11)

Country Link
US (1) US5508039A (fr)
EP (1) EP0608362A1 (fr)
JP (1) JPH07503232A (fr)
AU (1) AU660336B2 (fr)
CA (1) CA2116036A1 (fr)
FI (1) FI941761L (fr)
MX (1) MX9205981A (fr)
NZ (1) NZ244760A (fr)
PT (1) PT100973A (fr)
WO (1) WO1993007870A1 (fr)
ZA (1) ZA928011B (fr)

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US5591768A (en) * 1990-12-04 1997-01-07 State Of Oregan, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University Methods for treating circadian rhythm phase disturbances
US6638963B1 (en) 1990-12-04 2003-10-28 Oregon Health And Science University Methods for treating circadian rhythm disorders
IT1254995B (it) * 1992-06-24 1995-10-11 Farmaco contenente melatonina e/o agonisti, con somministrazione particolarmente efficace nelle patologie che interferiscono con i ritmi circandiani
US5449683A (en) * 1992-10-01 1995-09-12 Massachussetts Institute Of Technology Methods of inducing sleep using melatonin
WO1995001167A2 (fr) 1993-06-25 1995-01-12 Alza Corporation Incorporation d'un amide poly-n-vinylique a un systeme transdermique
US5385736A (en) * 1993-07-12 1995-01-31 Minnesota Mining And Manufacturing Company Transdermal melatonin delivery system
US5654325A (en) * 1993-11-18 1997-08-05 Eli Lilly And Company Melatonin derivatives for use in treating sleep disorders
US6180657B1 (en) * 1993-11-18 2001-01-30 Eli Lilly And Company Melatonin derivatives for use in treating desynchronization disorders
US5730721A (en) 1996-01-25 1998-03-24 Vesture Corporation Medical applicator and method
DE19713141A1 (de) * 1996-03-29 1997-10-30 Labtec Gmbh Transdermales System mit Melatonin
FR2751539B1 (fr) * 1996-07-25 1998-12-04 Oreal Nouvelles compositions topiques comprenant de tres faibles doses de melatonine ou ses derives et leur utilisation en cosmetique
CA2345492C (fr) * 1998-09-29 2009-12-22 Zars, Inc. Procedes et dispositifs servant a ameliorer l'administration de composes actifs sur le plan pharmaceutique
TR200201724T2 (tr) * 2000-01-05 2003-03-21 Neurim Pharmaceuticals (1991) Ltd. Antihipertansiyon ve buna bağlı belirtileri tedavi etmek için method ve formüller
DE10004790B4 (de) * 2000-02-01 2004-09-09 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreichung von Zaleplon, Verfahren zu seiner Herstellung und seine Verwendung
US20030021836A1 (en) * 2001-04-20 2003-01-30 Spencer Feldman Magnesium di-potassium EDTA complex and method of administration
DE10154324A1 (de) * 2001-11-06 2003-08-07 Merz Pharma Gmbh & Co Kgaa Topisch applizierbare Zusammensetzungen mit externer Wirkstoffdepotbildung, deren Herstellung sowie deren Verwendung
US20040033253A1 (en) * 2002-02-19 2004-02-19 Ihor Shevchuk Acyl opioid antagonists
US9119846B2 (en) 2003-04-29 2015-09-01 Neurim Pharmaceuticals (1991) Ltd. Method and composition for enhancing cognition in alzheimer's patients
IL155666A (en) 2003-04-29 2013-12-31 Neurim Pharma 1991 Insomnia treatment
US20040254202A1 (en) * 2003-06-13 2004-12-16 The Procter & Gamble Company Method of promoting sleep using topical administration of vasoactive agents
CA2541090C (fr) 2003-10-03 2013-04-16 Veijlen N.V. Utilisation de l'acide indole-acetique ou de derives dudit acide pour augmenter les niveaux de serum igf-1
EP1667678B1 (fr) 2003-10-03 2009-05-06 Veijlen N.V. Composition d'aliment pour animaux
CN101516255A (zh) * 2006-09-13 2009-08-26 皇家飞利浦电子股份有限公司 用于自动调整褪黑素的剂量和/或递送褪黑素的装置
AU2008228903B2 (en) 2007-03-19 2013-03-07 Vita Sciences, Llc Transdermal patch and method for delivery of vitamin B12
US20090047334A1 (en) * 2007-08-13 2009-02-19 Patricia Williams Transdermal patch for extended delivery of calcium
US8492331B2 (en) * 2008-03-27 2013-07-23 Nestec S.A. Methods for increasing absorption of peptides, peptidomimetics and other gastrointestinal transport protein substrates
US20100256197A1 (en) * 2009-04-02 2010-10-07 Silver Eagle Labs Nv, Llc Nicotine Dissolving Film With Or Without Menthol
US20100256215A1 (en) * 2009-04-02 2010-10-07 Silver Eagle Labs Nv, Llc Menthol-Melatonin Dissolving Film
US9186334B2 (en) 2009-05-04 2015-11-17 Nuvo Research Inc. Heat assisted lidocaine and tetracaine for transdermal analgesia
US9186273B2 (en) 2009-05-04 2015-11-17 Nuvo Research Inc. Methods of treating pains associated with neuroma, nerve entrapment, and other conditions
US9962369B2 (en) 2014-03-10 2018-05-08 Sprayable Holdings, Inc. Methods and compositions for transdermal delivery
CN107810003B (zh) * 2015-02-04 2022-05-03 索尔约瑟法梅内德斯公司 包含瓦伦托宁的透皮治疗系统及其作为药物的应用
KR102499141B1 (ko) * 2016-10-31 2023-02-13 신신제약 주식회사 수면장애 치료용 경피흡수제제
EP3743131B1 (fr) 2018-01-25 2025-03-05 Circadian Positioning Systems, Inc. Système de timbre pour surveiller et améliorer l'alignement du rythme circadien et du sommeil
US20200121507A1 (en) * 2018-10-18 2020-04-23 Moldex-Metric, Inc. Foam earplug with transdermal material
SE544626C2 (en) * 2020-03-05 2022-09-27 Nub Group Ab An earplug for administering a fluid agent into an ear canal

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3598123A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3797494A (en) * 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
US3598122A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3731683A (en) * 1971-06-04 1973-05-08 Alza Corp Bandage for the controlled metering of topical drugs to the skin
US4144317A (en) * 1975-05-30 1979-03-13 Alza Corporation Device consisting of copolymer having acetoxy groups for delivering drugs
US4031894A (en) * 1975-12-08 1977-06-28 Alza Corporation Bandage for transdermally administering scopolamine to prevent nausea
US4201211A (en) * 1977-07-12 1980-05-06 Alza Corporation Therapeutic system for administering clonidine transdermally
US4296324A (en) * 1979-11-02 1981-10-20 Santa Barbara Research Center Dual spectrum infrared fire sensor
US4286592A (en) * 1980-02-04 1981-09-01 Alza Corporation Therapeutic system for administering drugs to the skin
US4314557A (en) * 1980-05-19 1982-02-09 Alza Corporation Dissolution controlled active agent dispenser
US4379454A (en) * 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer
US4849226A (en) * 1981-06-29 1989-07-18 Alza Corporation Method for increasing oxygen supply by administering vasodilator
US4435180A (en) * 1982-05-25 1984-03-06 Alza Corporation Elastomeric active agent delivery system and method of use
US4559222A (en) * 1983-05-04 1985-12-17 Alza Corporation Matrix composition for transdermal therapeutic system
DE3466215D1 (en) * 1983-05-18 1987-10-22 Univ Monash The use of melatonin for the manufacture of a medicament
US4600723A (en) * 1983-05-18 1986-07-15 Monash University Method for minimizing disturbances in circadian rhythms of bodily performance and function
US4704282A (en) * 1984-06-29 1987-11-03 Alza Corporation Transdermal therapeutic system having improved delivery characteristics
US4588580B2 (en) * 1984-07-23 1999-02-16 Alaz Corp Transdermal administration of fentanyl and device therefor
US4573995A (en) * 1984-10-09 1986-03-04 Alza Corporation Transdermal therapeutic systems for the administration of naloxone, naltrexone and nalbuphine
US4645502A (en) * 1985-05-03 1987-02-24 Alza Corporation Transdermal delivery of highly ionized fat insoluble drugs
IT1187676B (it) * 1985-07-03 1987-12-23 Montefluos Spa Processo per la lubrificazione di organi accessori di cassette contenenti nastri magnetici
GB8517958D0 (en) * 1985-07-16 1985-08-21 Cellena Cell Eng Ag Compositions containing melatonin/homologues
US4654361A (en) * 1986-01-27 1987-03-31 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University Method of lowering intraocular pressure using melatonin
EP0249343B1 (fr) * 1986-06-13 1992-01-08 Alza Corporation Activation par l'humidité d'un système à libération transdermale des drogues
IL79264A0 (en) * 1986-06-27 1986-09-30 Univ Ramot Tryptamine derivatives,pharmaceutical compositions containing them and their use in an assay for melatonin receptors
US4908027A (en) * 1986-09-12 1990-03-13 Alza Corporation Subsaturated transdermal therapeutic system having improved release characteristics
US4788062A (en) * 1987-02-26 1988-11-29 Alza Corporation Transdermal administration of progesterone, estradiol esters, and mixtures thereof
US4816258A (en) * 1987-02-26 1989-03-28 Alza Corporation Transdermal contraceptive formulations
US5049387A (en) * 1987-03-09 1991-09-17 Alza Corporation Inducing skin tolerance to a sensitizing drug
US4855305A (en) * 1987-03-23 1989-08-08 Applied Medical Research Compositions and methods of effecting contraception utilizing melatonin
KR910006124B1 (ko) * 1987-08-17 1991-08-13 넬슨 리써취 앤드 디벨럽먼트 캄파니 멜라토닌 동족체
US4943435A (en) * 1987-10-05 1990-07-24 Pharmetrix Corporation Prolonged activity nicotine patch
GB8727099D0 (en) * 1987-11-19 1987-12-23 Cellena Cell Eng A G Compositions containing melantonin/homologues
US4945103A (en) * 1989-01-17 1990-07-31 Michael Cohen Method of treating pre-menstrual syndrome
US4948103A (en) * 1989-01-30 1990-08-14 Illinois Tool Works, Inc. Spring-loaded dampening actuator
NZ233697A (en) * 1989-05-17 1996-12-20 Applied Med Res Ltd Contraceptive composition comprising a melatonin analogue and a progestogen and/or an estrogen
US5071875A (en) * 1989-09-25 1991-12-10 Northwestern University Substituted 2-amidotetralins as melatonin agonists and antagonists
JPH03145419A (ja) * 1989-10-31 1991-06-20 Shiseido Co Ltd 紫外線老化の防御薬剤
US5242941A (en) * 1990-12-04 1993-09-07 State Of Oregon Methods of treating circadian rhythm disorders

Also Published As

Publication number Publication date
MX9205981A (es) 1993-04-01
FI941761A0 (fi) 1994-04-15
FI941761A7 (fi) 1994-04-15
WO1993007870A1 (fr) 1993-04-29
EP0608362A1 (fr) 1994-08-03
US5508039A (en) 1996-04-16
PT100973A (pt) 1994-06-30
AU660336B2 (en) 1995-06-22
AU2877892A (en) 1993-05-21
NZ244760A (en) 1997-02-24
FI941761L (fi) 1994-04-15
JPH07503232A (ja) 1995-04-06
CA2116036A1 (fr) 1993-04-29

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