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ZA9010065B - Improved menigococcal polysaccharide conjugate vaccine - Google Patents

Improved menigococcal polysaccharide conjugate vaccine

Info

Publication number
ZA9010065B
ZA9010065B ZA9010065A ZA9010065A ZA9010065B ZA 9010065 B ZA9010065 B ZA 9010065B ZA 9010065 A ZA9010065 A ZA 9010065A ZA 9010065 A ZA9010065 A ZA 9010065A ZA 9010065 B ZA9010065 B ZA 9010065B
Authority
ZA
South Africa
Prior art keywords
menigococcal
improved
conjugate vaccine
polysaccharide conjugate
polysaccharide
Prior art date
Application number
ZA9010065A
Other languages
English (en)
Inventor
Harold J Jennings
Francis Michon
Original Assignee
Ca Nat Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ca Nat Research Council filed Critical Ca Nat Research Council
Publication of ZA9010065B publication Critical patent/ZA9010065B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1228—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K16/1232—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia from Escherichia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
ZA9010065A 1989-12-14 1990-12-14 Improved menigococcal polysaccharide conjugate vaccine ZA9010065B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44819589A 1989-12-14 1989-12-14

Publications (1)

Publication Number Publication Date
ZA9010065B true ZA9010065B (en) 1992-02-26

Family

ID=23779371

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9010065A ZA9010065B (en) 1989-12-14 1990-12-14 Improved menigococcal polysaccharide conjugate vaccine

Country Status (30)

Country Link
US (3) US5576002A (fr)
EP (1) EP0504202B1 (fr)
JP (1) JP2637845B2 (fr)
KR (1) KR0158436B1 (fr)
CN (4) CN1049223C (fr)
AR (1) AR243934A1 (fr)
AT (1) ATE121947T1 (fr)
AU (1) AU641715B2 (fr)
BR (1) BR9007917A (fr)
CA (1) CA2071811C (fr)
CZ (1) CZ283530B6 (fr)
DE (1) DE69019164T2 (fr)
DK (1) DK0504202T3 (fr)
ES (1) ES2071288T3 (fr)
FI (2) FI104539B (fr)
HR (1) HRP920872A2 (fr)
HU (2) HU218146B (fr)
IE (1) IE68414B1 (fr)
IL (1) IL96676A (fr)
IN (1) IN171747B (fr)
NO (2) NO305275B1 (fr)
NZ (1) NZ236471A (fr)
PH (1) PH30305A (fr)
PL (2) PL166659B1 (fr)
RO (1) RO111416B1 (fr)
RU (1) RU2105568C1 (fr)
SI (1) SI20008B (fr)
WO (1) WO1991008772A1 (fr)
YU (1) YU24391A (fr)
ZA (1) ZA9010065B (fr)

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US5648241A (en) * 1989-09-15 1997-07-15 The General Hospital Corporation Conjugate vaccine against group B streptococcus
RU2105568C1 (ru) * 1989-12-14 1998-02-27 Нэшнл Рисерч Каунсл Оф Канада Полисахарид neisseria meningitidis с модифицированной группой b, конъюгированный антиген, вакцина против менингита группы b и способ индукции ответа антител к менингиту группы b
JP4163251B2 (ja) * 1992-09-24 2008-10-08 ブリガーム・アンド・ウーメンズ・ホスピタル・インコーポレーテッド グループｂストレプトコッカス・タイプ▲ｉｉ▼およびタイプ▲ｖ▼多糖−蛋白質接合ワクチン
US6153406A (en) * 1993-07-23 2000-11-28 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane protein P2 from Haemophilus influenzae type B
US5439808A (en) * 1993-07-23 1995-08-08 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
US5679654A (en) * 1994-09-02 1997-10-21 Brigham & Women's Hospital, Inc. Capsular polysaccharide immunomodulator
US5700787A (en) * 1994-09-02 1997-12-23 Brigham & Women's Hospital, Inc. Capsular polysaccharide immunomodulator
US5747287A (en) * 1995-04-28 1998-05-05 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
US5811102A (en) * 1995-06-07 1998-09-22 National Research Council Of Canada Modified meningococcal polysaccharide conjugate vaccines
US6284884B1 (en) 1995-06-07 2001-09-04 North American Vaccine, Inc. Antigenic group B streptococcus type II and type III polysaccharide fragments having a 2,5-anhydro-D-mannose terminal structure and conjugate vaccine thereof
WO1996040242A1 (fr) * 1995-06-07 1996-12-19 Smithkline Beecham Biologicals S.A. Vaccins comprenant un conjugue antigene de polysaccharide-proteine porteuse et une proteine porteuse libre
ZA97248B (en) * 1996-01-18 1997-07-18 Rohm & Haas Method for identifying and quantifying polymers utilizing immunoassay techniques
ATE252602T1 (de) * 1996-08-27 2003-11-15 Chiron Corp Meningokokkus b-epitop ausbildende monoklonale antikoerper und deren verwendung zur herstellung von impfstoffzusammenstellungen
ATE208629T1 (de) 1996-08-27 2001-11-15 Chiron Corp Neisseria meningitidis serogruppe b glykokonjugate und verfahren zu deren verwendung
US6426074B1 (en) 1997-03-19 2002-07-30 The Brigham And Women's Hospital Inc. Group B Streptococcus vaccine
WO1998058670A1 (fr) 1997-06-24 1998-12-30 Chiron Corporation Procedes permettant d'immuniser des adultes grace a des compositions de vaccins anti-meningococcique
ATE505478T1 (de) 1997-08-27 2011-04-15 Novartis Vaccines & Diagnostic Molekular-mimetika von meningokokkalen b epitopen
CA2316975C (fr) 1997-12-23 2009-03-24 North American Vaccine, Inc. Procedures permettant d'extraire et d'isoler des polysaccharides capsulaires bacteriens destines a etre utilises seuls, en tant que vaccins ou, lies a des proteines, en tant que vaccins conjugues
PL346645A1 (en) * 1998-08-19 2002-02-25 North American Vaccine IMMUNOGENIC β-PROPIONAMIDO-LINKED POLYSACCHARIDE PROTEIN CONJUGATE USEFUL AS A VACCINE PRODUCED USING AN N-ACRYLOYLATED POLYSACCHARIDE
CA2340692A1 (fr) * 1998-08-19 2000-03-02 North American Vaccine, Inc. Conjugue de proteine-polysaccharide immunogene a liaison beta-propionamido, utile comme vaccin etabli au moyen d'un polysaccharide n-acryloyle
US6436653B1 (en) 1998-12-15 2002-08-20 Exiqon A/S Method for introduction of reporter groups into bacterial lipopolysaccharide-derived carbohydrates and the subsequent coupling of such derivatives onto solid surfaces
US7083777B1 (en) * 1999-04-02 2006-08-01 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
US6518037B2 (en) * 1999-11-12 2003-02-11 University Of Iowa Research Foundation Two-component system that controls bacterial membrane synthesis
GB9928196D0 (en) * 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
GB0011108D0 (en) * 2000-05-08 2000-06-28 Microscience Ltd Virulence gene and protein and their use
SV2003000753A (es) 2000-12-05 2003-06-16 Brigham & Womens Hospital Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
CN1306956C (zh) 2001-04-17 2007-03-28 希龙公司 诱导功能活性抗体的脑膜炎球菌b抗原表位的分子模拟物
GB0115176D0 (en) * 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
GB0121591D0 (en) * 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
AR045702A1 (es) 2001-10-03 2005-11-09 Chiron Corp Composiciones de adyuvantes.
MXPA04009339A (es) * 2002-03-26 2005-01-25 Chiron Srl Sacaridos modificados que tienen estabilidad mejorada en agua.
WO2003094960A2 (fr) * 2002-05-14 2003-11-20 Chiron Srl Vaccins combines destines a etre administres aux muqueuses pour l'immunisation contre la meningite bacterienne
RU2364418C2 (ru) * 2002-08-02 2009-08-20 ГлаксоСмитКлайн Байолоджикалз с.а. ВАКЦИННЫЕ КОМПОЗИЦИИ, СОДЕРЖАЩИЕ ЛИПОПОЛИСАХАРИДЫ ИММУНОТИПА L2 И/ИЛИ L3, ПРОИСХОДЯЩИЕ ИЗ ШТАММА NEISSERIA MENINGITIDIS IgtB-
GB0227346D0 (en) * 2002-11-22 2002-12-31 Chiron Spa 741
AU2004227852B2 (en) * 2003-03-31 2010-01-14 The Brigham And Women's Hospital, Inc. Zwitterionic immunomodulators for the treatment of asthma and allergy
US7731967B2 (en) 2003-04-30 2010-06-08 Novartis Vaccines And Diagnostics, Inc. Compositions for inducing immune responses
KR101113726B1 (ko) 2003-08-12 2012-02-27 리폭센 테크놀로지즈 리미티드 단백질 유도 및 컨쥬게이션용 시알산 유도체
KR20070060069A (ko) 2004-06-23 2007-06-12 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 다당류 유도체 및 면역반응의 유도에서의 용도
US8148335B2 (en) 2004-06-23 2012-04-03 Children's Hospital & Research Center Oakland De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy
GB0428394D0 (en) * 2004-12-24 2005-02-02 Chiron Srl Saccharide conjugate vaccines
PL2878307T3 (pl) 2005-06-27 2020-01-31 Glaxosmithkline Biologicals S.A. Kompozycja immunogenna
US8206726B2 (en) 2006-02-06 2012-06-26 The Brigham And Women's Hospital, Inc. Zwitterionic polysaccharides for promotion of immune system maturation and health
GB0611914D0 (en) 2006-06-15 2006-07-26 Teti Giuseppe Peptides that mimic non-human cross-reactive protective epitopes of the group Bmeningococcal capsulsar polysaccharide
EP1872791A1 (fr) * 2006-06-30 2008-01-02 Institut Pasteur Utilisation de polysaccharides bactériens pour empêcher la formation d'un film biologique
EP2170391B1 (fr) * 2007-06-20 2017-01-18 Pfizer Ireland Pharmaceuticals Polysaccharides modifiés pour vaccins conjugués
EP3067048B1 (fr) 2007-12-07 2018-02-14 GlaxoSmithKline Biologicals SA Compositions d'induction des réponses immunitaires
WO2010083477A2 (fr) 2009-01-16 2010-07-22 University Of Maryland, Baltimore Vaccin à large spectre contre les salmonelles non typhoïdiques
WO2013009945A1 (fr) 2011-07-12 2013-01-17 The Brigham And Women's Hospital, Inc. Compositions de psa contenant des lipides, procédés d'isolement et procédés pour les utiliser
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CA2997211A1 (fr) 2015-08-19 2017-02-23 President And Fellows Of Harvard College Compositions de psa lipides et procedes associes
CA3030974A1 (fr) 2016-07-15 2018-01-18 President And Fellows Of Harvard College Compositions de glycolipide et procedes d'utilisation
SG10202111092UA (en) * 2017-01-31 2021-11-29 Pfizer Neisseria meningitidis compositions and methods thereof

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Also Published As

Publication number Publication date
US5683699A (en) 1997-11-04
CZ628490A3 (en) 1997-12-17
RO111416B1 (ro) 1996-10-31
PL166659B1 (pl) 1995-06-30
YU24391A (sh) 1995-12-04
CN1072506C (zh) 2001-10-10
CN1049223C (zh) 2000-02-09
NO973311L (no) 1992-08-14
BR9007917A (pt) 1992-10-20
FI922737A0 (fi) 1992-06-12
PL288271A1 (en) 1991-12-16
IL96676A (en) 1996-09-12
NO973311D0 (no) 1997-07-17
SI20008B (en) 2001-02-28
IL96676A0 (en) 1991-09-16
WO1991008772A1 (fr) 1991-06-27
US5576002A (en) 1996-11-19
CN1096516A (zh) 1994-12-21
CN1055541A (zh) 1991-10-23
DE69019164T2 (de) 1995-09-07
DE69019164D1 (de) 1995-06-08
IE68414B1 (en) 1996-06-12
CZ283530B6 (cs) 1998-04-15
CA2071811C (fr) 2003-11-04
IE904513A1 (en) 1991-06-19
DK0504202T3 (da) 1995-10-02
NO922316D0 (no) 1992-06-12
EP0504202B1 (fr) 1995-05-03
CN1036504C (zh) 1997-11-26
PL166035B1 (pl) 1995-03-31
JP2637845B2 (ja) 1997-08-06
CN1100428A (zh) 1995-03-22
AR243934A1 (es) 1993-09-30
FI104539B (fi) 2000-02-29
AU6898791A (en) 1991-07-18
FI19991917L (fi) 1999-09-09
ATE121947T1 (de) 1995-05-15
NZ236471A (en) 1992-10-28
US5902586A (en) 1999-05-11
NO307835B1 (no) 2000-06-05
FI19991917A7 (fi) 1999-09-09
HU9201966D0 (en) 1992-10-28
HUT64480A (en) 1994-01-28
PH30305A (en) 1997-02-20
SI20008A (sl) 2000-02-29
ES2071288T3 (es) 1995-06-16
IN171747B (fr) 1992-12-26
HU218146B (hu) 2000-06-28
KR0158436B1 (ko) 1998-12-01
NO922316L (no) 1992-08-14
AU641715B2 (en) 1993-09-30
NO305275B1 (no) 1999-05-03
JPH05505392A (ja) 1993-08-12
RU2105568C1 (ru) 1998-02-27
CA2071811A1 (fr) 1991-06-15
CN1100656A (zh) 1995-03-29
EP0504202A1 (fr) 1992-09-23
HRP920872A2 (en) 1997-06-30
CN1036522C (zh) 1997-11-26

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