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SI20008B - Improved meningococcal polysaccharide conjugate vaccine - Google Patents

Improved meningococcal polysaccharide conjugate vaccine Download PDF

Info

Publication number
SI20008B
SI20008B SI9110243A SI9110243A SI20008B SI 20008 B SI20008 B SI 20008B SI 9110243 A SI9110243 A SI 9110243A SI 9110243 A SI9110243 A SI 9110243A SI 20008 B SI20008 B SI 20008B
Authority
SI
Slovenia
Prior art keywords
group
butanoyl
polysaccharide
pentanoyl
modified polysaccharide
Prior art date
Application number
SI9110243A
Other languages
English (en)
Slovenian (sl)
Other versions
SI20008A (sl
Inventor
Harold J Jennings
Francis Michon
Original Assignee
Ca Nat Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ca Nat Research Council filed Critical Ca Nat Research Council
Publication of SI20008A publication Critical patent/SI20008A/sl
Publication of SI20008B publication Critical patent/SI20008B/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1228—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K16/1232—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia from Escherichia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
SI9110243A 1989-12-14 1990-12-14 Improved meningococcal polysaccharide conjugate vaccine SI20008B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44819589A 1989-12-14 1989-12-14
YU24391A YU24391A (sh) 1989-12-14 1990-12-14 Poboljšana meningokokna polisaharid kon-jugovana vakcina

Publications (2)

Publication Number Publication Date
SI20008A SI20008A (sl) 2000-02-29
SI20008B true SI20008B (en) 2001-02-28

Family

ID=23779371

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9110243A SI20008B (en) 1989-12-14 1990-12-14 Improved meningococcal polysaccharide conjugate vaccine

Country Status (30)

Country Link
US (3) US5576002A (fr)
EP (1) EP0504202B1 (fr)
JP (1) JP2637845B2 (fr)
KR (1) KR0158436B1 (fr)
CN (4) CN1049223C (fr)
AR (1) AR243934A1 (fr)
AT (1) ATE121947T1 (fr)
AU (1) AU641715B2 (fr)
BR (1) BR9007917A (fr)
CA (1) CA2071811C (fr)
CZ (1) CZ283530B6 (fr)
DE (1) DE69019164T2 (fr)
DK (1) DK0504202T3 (fr)
ES (1) ES2071288T3 (fr)
FI (2) FI104539B (fr)
HR (1) HRP920872A2 (fr)
HU (2) HU9201966D0 (fr)
IE (1) IE68414B1 (fr)
IL (1) IL96676A (fr)
IN (1) IN171747B (fr)
NO (2) NO305275B1 (fr)
NZ (1) NZ236471A (fr)
PH (1) PH30305A (fr)
PL (2) PL166659B1 (fr)
RO (1) RO111416B1 (fr)
RU (1) RU2105568C1 (fr)
SI (1) SI20008B (fr)
WO (1) WO1991008772A1 (fr)
YU (1) YU24391A (fr)
ZA (1) ZA9010065B (fr)

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ATE121947T1 (de) * 1989-12-14 1995-05-15 Ca Nat Research Council Verbessertes meningokokkale polysaccharidkonjugatvakzin.
EP0667787B1 (fr) * 1992-09-24 2001-07-18 Brigham And Women's Hospital Vaccins a conjugues de proteine-polysaccharide de streptococcus de type ii et de type v du groupe b
US6153406A (en) * 1993-07-23 2000-11-28 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane protein P2 from Haemophilus influenzae type B
US5439808A (en) * 1993-07-23 1995-08-08 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
US5700787A (en) * 1994-09-02 1997-12-23 Brigham & Women's Hospital, Inc. Capsular polysaccharide immunomodulator
US5679654A (en) * 1994-09-02 1997-10-21 Brigham & Women's Hospital, Inc. Capsular polysaccharide immunomodulator
US5747287A (en) * 1995-04-28 1998-05-05 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
US6284884B1 (en) 1995-06-07 2001-09-04 North American Vaccine, Inc. Antigenic group B streptococcus type II and type III polysaccharide fragments having a 2,5-anhydro-D-mannose terminal structure and conjugate vaccine thereof
DE69615362T3 (de) * 1995-06-07 2006-07-20 Smithkline Beecham Biologicals S.A. Impfstoff mit einem polysaccharidantigen-trägerprotein-konjugat und einem trägerprotein
US5811102A (en) 1995-06-07 1998-09-22 National Research Council Of Canada Modified meningococcal polysaccharide conjugate vaccines
ZA97248B (en) * 1996-01-18 1997-07-18 Rohm & Haas Method for identifying and quantifying polymers utilizing immunoassay techniques
US6048527A (en) * 1996-08-27 2000-04-11 Chiron Corporation Antibodies that define unique Meningococcal B epitopes and vaccine compositions
JP4162267B2 (ja) 1996-08-27 2008-10-08 カイロン コーポレイション Ｎｅｉｓｓｅｒｉａ ｍｅｎｉｎｇｉｔｉｄｉｓ血清型Ｂ複合糖質およびその使用法
US6426074B1 (en) 1997-03-19 2002-07-30 The Brigham And Women's Hospital Inc. Group B Streptococcus vaccine
US6413520B1 (en) 1997-06-24 2002-07-02 Chiron Corporation Methods of immunizing adults using anti-meningococcal vaccine compositions
EP1007546B1 (fr) * 1997-08-27 2009-01-21 Novartis Vaccines and Diagnostics, Inc. Mimetiques moleculaires d' epitopes meningococci b
ES2346022T3 (es) 1997-12-23 2010-10-07 Baxter Healthcare S.A. Procedimiento para la extraccion y el aislamiento de polisacaridos capsulares bacterianos para su uso como vacunas o ligandos a proteinas como vacunas de conjugados.
PL346645A1 (en) * 1998-08-19 2002-02-25 North American Vaccine IMMUNOGENIC β-PROPIONAMIDO-LINKED POLYSACCHARIDE PROTEIN CONJUGATE USEFUL AS A VACCINE PRODUCED USING AN N-ACRYLOYLATED POLYSACCHARIDE
CN1263510C (zh) * 1998-08-19 2006-07-12 巴克斯特健康护理股份有限公司 多糖－蛋白质缀合物或寡糖－蛋白质缀合物、其制备方法及其应用
US6436653B1 (en) 1998-12-15 2002-08-20 Exiqon A/S Method for introduction of reporter groups into bacterial lipopolysaccharide-derived carbohydrates and the subsequent coupling of such derivatives onto solid surfaces
US7083777B1 (en) * 1999-04-02 2006-08-01 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
US6518037B2 (en) * 1999-11-12 2003-02-11 University Of Iowa Research Foundation Two-component system that controls bacterial membrane synthesis
GB9928196D0 (en) * 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
GB0011108D0 (en) * 2000-05-08 2000-06-28 Microscience Ltd Virulence gene and protein and their use
SV2003000753A (es) 2000-12-05 2003-06-16 Brigham & Womens Hospital Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
RU2322451C2 (ru) * 2001-04-17 2008-04-20 Новартис Вэксинс Энд Диагностикс, Инк. Молекулярные миметики эпитопов менингококка в, которые вызывают выработку функционально активных антител
GB0115176D0 (en) * 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
GB0121591D0 (en) * 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
AR045702A1 (es) 2001-10-03 2005-11-09 Chiron Corp Composiciones de adyuvantes.
BR0308768A (pt) * 2002-03-26 2005-02-15 Chiron Srl Sacarìdeos modificados possuindo estabilidade melhorada em água
RU2378008C2 (ru) * 2002-05-14 2010-01-10 Новартис Вэксинес Энд Дайэгностикс С.Р.Л. Комбинированные вакцины против бактериального менингита для введения через слизистую оболочку
RU2317106C2 (ru) * 2002-08-02 2008-02-20 ГлаксоСмитКлайн Байолоджикалз с.а. Нейссериальные вакцинные композиции, содержащие комбинацию антигенов
GB0227346D0 (en) * 2002-11-22 2002-12-31 Chiron Spa 741
WO2004089407A2 (fr) * 2003-03-31 2004-10-21 The Brigham And Women's Hospital, Inc. Immunomodulateurs zwitterioniques destines au traitement de l'asthme et des allergies
US7731967B2 (en) 2003-04-30 2010-06-08 Novartis Vaccines And Diagnostics, Inc. Compositions for inducing immune responses
WO2005016974A1 (fr) 2003-08-12 2005-02-24 Lipoxen Technologies Limited Derive d'acide sialique destine a la derivatisation et a la conjugaison proteinique
US8148335B2 (en) 2004-06-23 2012-04-03 Children's Hospital & Research Center Oakland De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy
AU2005258301A1 (en) 2004-06-23 2006-01-05 Children's Hospital & Research Center At Oakland Polysaccharide derivatives and uses in induction of an immune response
GB0428394D0 (en) * 2004-12-24 2005-02-02 Chiron Srl Saccharide conjugate vaccines
WO2007000341A2 (fr) 2005-06-27 2007-01-04 Glaxosmithkline Biologicals S.A. Composition immunogène
US8206726B2 (en) 2006-02-06 2012-06-26 The Brigham And Women's Hospital, Inc. Zwitterionic polysaccharides for promotion of immune system maturation and health
GB0611914D0 (en) 2006-06-15 2006-07-26 Teti Giuseppe Peptides that mimic non-human cross-reactive protective epitopes of the group Bmeningococcal capsulsar polysaccharide
EP1872791A1 (fr) 2006-06-30 2008-01-02 Institut Pasteur Utilisation de polysaccharides bactériens pour empêcher la formation d'un film biologique
CA2692069C (fr) * 2007-06-20 2016-10-18 Baxter Healthcare S.A. Polysaccharides modifies pour vaccins conjugues
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EP2387417B1 (fr) 2009-01-16 2016-05-11 University of Maryland, Baltimore Vaccin à large spectre contre les salmonelles non typhoïdiques
JP6273200B2 (ja) 2011-07-12 2018-01-31 ザ・ブリガーム・アンド・ウーメンズ・ホスピタル・インコーポレーテッド 脂質含有ｐｓａ組成物、その単離の方法および使用の方法
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Also Published As

Publication number Publication date
ZA9010065B (en) 1992-02-26
JPH05505392A (ja) 1993-08-12
EP0504202A1 (fr) 1992-09-23
AU641715B2 (en) 1993-09-30
RU2105568C1 (ru) 1998-02-27
US5683699A (en) 1997-11-04
BR9007917A (pt) 1992-10-20
FI104539B (fi) 2000-02-29
DK0504202T3 (da) 1995-10-02
IL96676A0 (en) 1991-09-16
DE69019164D1 (de) 1995-06-08
NO973311L (no) 1992-08-14
CN1055541A (zh) 1991-10-23
PL166659B1 (pl) 1995-06-30
IN171747B (fr) 1992-12-26
RO111416B1 (ro) 1996-10-31
NO922316L (no) 1992-08-14
US5902586A (en) 1999-05-11
CN1036522C (zh) 1997-11-26
AR243934A1 (es) 1993-09-30
HU9201966D0 (en) 1992-10-28
FI922737A0 (fi) 1992-06-12
NZ236471A (en) 1992-10-28
NO305275B1 (no) 1999-05-03
PL166035B1 (pl) 1995-03-31
CN1096516A (zh) 1994-12-21
HRP920872A2 (en) 1997-06-30
KR0158436B1 (ko) 1998-12-01
CZ283530B6 (cs) 1998-04-15
IE904513A1 (en) 1991-06-19
HUT64480A (en) 1994-01-28
HU218146B (hu) 2000-06-28
CA2071811A1 (fr) 1991-06-15
CZ628490A3 (en) 1997-12-17
PH30305A (en) 1997-02-20
NO922316D0 (no) 1992-06-12
EP0504202B1 (fr) 1995-05-03
CN1100428A (zh) 1995-03-22
ES2071288T3 (es) 1995-06-16
DE69019164T2 (de) 1995-09-07
WO1991008772A1 (fr) 1991-06-27
CA2071811C (fr) 2003-11-04
PL288271A1 (en) 1991-12-16
US5576002A (en) 1996-11-19
FI19991917A7 (fi) 1999-09-09
IL96676A (en) 1996-09-12
SI20008A (sl) 2000-02-29
JP2637845B2 (ja) 1997-08-06
AU6898791A (en) 1991-07-18
CN1100656A (zh) 1995-03-29
CN1036504C (zh) 1997-11-26
FI19991917L (fi) 1999-09-09
YU24391A (sh) 1995-12-04
CN1049223C (zh) 2000-02-09
NO307835B1 (no) 2000-06-05
ATE121947T1 (de) 1995-05-15
IE68414B1 (en) 1996-06-12
CN1072506C (zh) 2001-10-10
NO973311D0 (no) 1997-07-17

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Effective date: 20090910