ZA899028B - Compound for treatment for autoimmune diseases - Google Patents
Compound for treatment for autoimmune diseasesInfo
- Publication number
- ZA899028B ZA899028B ZA899028A ZA899028A ZA899028B ZA 899028 B ZA899028 B ZA 899028B ZA 899028 A ZA899028 A ZA 899028A ZA 899028 A ZA899028 A ZA 899028A ZA 899028 B ZA899028 B ZA 899028B
- Authority
- ZA
- South Africa
- Prior art keywords
- compound
- treatment
- autoimmune diseases
- naltrexone
- nalmefene
- Prior art date
Links
- 208000023275 Autoimmune disease Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- DQCKKXVULJGBQN-XFWGSAIBSA-N naltrexone Chemical compound N1([C@@H]2CC3=CC=C(C=4O[C@@H]5[C@](C3=4)([C@]2(CCC5=O)O)CC1)O)CC1CC1 DQCKKXVULJGBQN-XFWGSAIBSA-N 0.000 abstract 3
- WJBLNOPPDWQMCH-MBPVOVBZSA-N Nalmefene Chemical compound N1([C@@H]2CC3=CC=C(C=4O[C@@H]5[C@](C3=4)([C@]2(CCC5=C)O)CC1)O)CC1CC1 WJBLNOPPDWQMCH-MBPVOVBZSA-N 0.000 abstract 2
- 229960005297 nalmefene Drugs 0.000 abstract 2
- 229960003086 naltrexone Drugs 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 239000003887 narcotic antagonist Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/284,615 US4857533A (en) | 1988-12-15 | 1988-12-15 | Method of treatment for autoimmune diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA899028B true ZA899028B (en) | 1990-08-29 |
Family
ID=23090868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA899028A ZA899028B (en) | 1988-12-15 | 1989-11-27 | Compound for treatment for autoimmune diseases |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4857533A (xx) |
| EP (1) | EP0373744B1 (xx) |
| JP (1) | JPH07555B2 (xx) |
| AT (1) | ATE107508T1 (xx) |
| AU (1) | AU617494B2 (xx) |
| CA (1) | CA1333569C (xx) |
| DE (1) | DE68916387T2 (xx) |
| DK (1) | DK630789A (xx) |
| IL (1) | IL92269A (xx) |
| NO (1) | NO894942L (xx) |
| ZA (1) | ZA899028B (xx) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5013739A (en) * | 1986-10-07 | 1991-05-07 | Bernard Bihari | Method of treating chronic fatigue syndrome using an opiate receptor antagonist |
| US4877791A (en) * | 1988-11-01 | 1989-10-31 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for interestitial cystitis |
| US5348729A (en) * | 1988-11-30 | 1994-09-20 | The United States Of America As Represented By The Department Of Health And Human Services | Evaluative means for detecting inflammatory reactivity |
| US4863928A (en) * | 1989-01-04 | 1989-09-05 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for arthritic and inflammatory diseases |
| JP2906654B2 (ja) * | 1989-11-28 | 1999-06-21 | 東レ株式会社 | 免疫抑制剤及びその製造方法 |
| US5086058A (en) * | 1990-06-04 | 1992-02-04 | Alko Ltd. | Method for treating alcoholism with nalmefene |
| US5376662A (en) * | 1993-12-08 | 1994-12-27 | Ockert; David M. | Method of attenuating nerve injury induced pain |
| SE9304236D0 (sv) * | 1993-12-22 | 1993-12-22 | Astra Ab | New use |
| US5878750A (en) * | 1996-11-14 | 1999-03-09 | Clemens; Anton H. | Method of treating the syndrome of coronary heart disease risk factors in humans |
| US6203813B1 (en) | 1997-01-13 | 2001-03-20 | Lance L. Gooberman | Pharmaceutical delivery device and method of preparation therefor |
| US6262062B1 (en) | 2000-08-15 | 2001-07-17 | Cpd, Llc | Method of treating the syndrome of coronary heart disease risk factors in humans |
| US6846831B2 (en) | 2000-08-15 | 2005-01-25 | Cpd, Llc | Method of treating the syndrome of lipodystrophy |
| US6528520B2 (en) | 2000-08-15 | 2003-03-04 | Cpd, Llc | Method of treating the syndrome of coronary heart disease risk factors in humans |
| US7501433B2 (en) * | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US6972291B2 (en) * | 2002-07-02 | 2005-12-06 | Bernstein Richard K | Method for reducing food intake |
| BRPI0409133B8 (pt) | 2003-04-08 | 2021-05-25 | Progenics Pharm Inc | preparações farmacêuticas estavéis compreendendo metilnaltrexona |
| US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US7285544B2 (en) * | 2003-11-18 | 2007-10-23 | Bernstein Eric F | Use of nitroxides in treating skin disease |
| CA2580694A1 (en) * | 2004-09-23 | 2006-03-30 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| US9662325B2 (en) | 2005-03-07 | 2017-05-30 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
| US8524731B2 (en) | 2005-03-07 | 2013-09-03 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
| US8518962B2 (en) | 2005-03-07 | 2013-08-27 | The University Of Chicago | Use of opioid antagonists |
| BRPI0608818A2 (pt) | 2005-03-07 | 2010-01-26 | Univ Chicago | uso de antagonista opióides para atenuação de proliferação e migração de células endoteliais |
| GB0509052D0 (en) * | 2005-05-04 | 2005-06-08 | Aimsco Ltd | Combination therapy |
| AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
| AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
| US20070259939A1 (en) * | 2006-05-04 | 2007-11-08 | Accelerated Technologies | Using naltrexone as a multi-purpose health supplement to improve the human condition and preventing multiple diseases and infirmities by stimulating immune system vitality and robustness |
| CA2682125C (en) | 2007-03-29 | 2015-06-16 | Progenics Pharmaceuticals, Inc. | Peripheral opioid receptor antagonists and uses thereof |
| PT2139890E (pt) | 2007-03-29 | 2014-09-03 | Wyeth Llc | Antagonistas do receptor opióide periférico e respectivas utilizações |
| EP2134718A2 (en) | 2007-03-29 | 2009-12-23 | Progenics Pharmaceuticals, Inc. | Crystal forms of (r)-n-methylnaltrexone bromide and uses thereof |
| CA2713568C (en) | 2008-02-06 | 2016-09-20 | Progenics Pharmaceuticals, Inc. | Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone |
| AU2009225434B2 (en) | 2008-03-21 | 2014-05-22 | The University Of Chicago | Treatment with opioid antagonists and mTOR inhibitors |
| US20110165232A1 (en) * | 2008-09-16 | 2011-07-07 | Ak Kimya Ithalat-Ihracat Ve Sanayii Anonim Sirketi | Use of Opioid Antagonists for the Preparation of a Medicament in the Treatment of Retinal Degenerative Diseases |
| CA2676881C (en) | 2008-09-30 | 2017-04-25 | Wyeth | Peripheral opioid receptor antagonists and uses thereof |
| TR201002473A2 (tr) | 2010-03-31 | 2011-09-21 | Mustafa Nevzat �La� Sanay�� A.�. | Herpes zoster hastalığının bır opiat reseptör antagonist kullanılarak tedavi yöntemi. |
| US20120252831A1 (en) * | 2011-03-31 | 2012-10-04 | Mustafa Nevzat Ilac Sanayii A.S. | Compositions of opioid antagonists and methods for treating scleroderma therewith |
| US9757372B2 (en) * | 2015-03-25 | 2017-09-12 | Taiwanj Pharmaceuticals Co., Ltd. | Toll-like receptor 4 antagonists and use in autoimmune liver diseases |
| KR102688278B1 (ko) | 2015-12-22 | 2024-07-26 | 조게닉스 인터내셔널 리미티드 | 펜플루라민 조성물 및 그 제조 방법 |
| EP3939570A1 (en) * | 2016-02-18 | 2022-01-19 | Immune Therapeutics, Inc. | Naltrexone for treating or preventing autoimmune and inflammatory diseases |
| JP2022547619A (ja) | 2019-09-16 | 2022-11-14 | フィジーン、エルエルシー | 椎間板変性疾患の治療、及び繊維芽細胞ならし培地によるタンパク質グリカン合成の刺激、並びにその製剤 |
| AU2022232414B2 (en) * | 2021-03-09 | 2025-06-05 | Inventage Lab Inc. | Sustained formulation for prevention or treatment of autoimmune disease containing naltrexone and method using same |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU538186B2 (en) * | 1980-03-07 | 1984-08-02 | Scotia Holdings Plc | Prostaglandin precursors |
| HU196376B (en) * | 1985-05-23 | 1988-11-28 | Sandoz Ag | Process for preparing morphinane derivatives and pharmaceutical compositions containing such compounds |
| FR2609632B1 (fr) * | 1987-01-21 | 1991-03-29 | Shelly Marc | Nouvelle application therapeutique de la 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinon-6-one et les compositions pharmaceutiques destinees a cet usage |
| US4880813A (en) * | 1988-07-22 | 1989-11-14 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for allergic rhinitis |
| DK160590C (da) * | 1988-09-12 | 1991-09-16 | Fls Airloq As | Fremgangsmaade til detektering af en gasart ved hjaelp af fotoakustisk spektroskopi |
| US4877791A (en) * | 1988-11-01 | 1989-10-31 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for interestitial cystitis |
| US4863928A (en) * | 1989-01-04 | 1989-09-05 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for arthritic and inflammatory diseases |
-
1988
- 1988-12-15 US US07/284,615 patent/US4857533A/en not_active Expired - Fee Related
-
1989
- 1989-07-07 AT AT89306922T patent/ATE107508T1/de not_active IP Right Cessation
- 1989-07-07 EP EP89306922A patent/EP0373744B1/en not_active Expired - Lifetime
- 1989-07-07 DE DE68916387T patent/DE68916387T2/de not_active Expired - Fee Related
- 1989-07-19 AU AU38279/89A patent/AU617494B2/en not_active Ceased
- 1989-07-20 JP JP1190410A patent/JPH07555B2/ja not_active Expired - Lifetime
- 1989-09-27 CA CA000613707A patent/CA1333569C/en not_active Expired - Fee Related
- 1989-11-10 IL IL9226989A patent/IL92269A/en not_active IP Right Cessation
- 1989-11-27 ZA ZA899028A patent/ZA899028B/xx unknown
- 1989-12-08 NO NO89894942A patent/NO894942L/no unknown
- 1989-12-13 DK DK630789A patent/DK630789A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH07555B2 (ja) | 1995-01-11 |
| NO894942D0 (no) | 1989-12-08 |
| AU617494B2 (en) | 1991-11-28 |
| IL92269A0 (en) | 1990-07-26 |
| EP0373744A2 (en) | 1990-06-20 |
| US4857533A (en) | 1989-08-15 |
| IL92269A (en) | 1994-04-12 |
| NO894942L (no) | 1990-06-18 |
| DK630789A (da) | 1990-06-16 |
| DK630789D0 (da) | 1989-12-13 |
| ATE107508T1 (de) | 1994-07-15 |
| CA1333569C (en) | 1994-12-20 |
| JPH02184627A (ja) | 1990-07-19 |
| EP0373744A3 (en) | 1991-09-18 |
| DE68916387T2 (de) | 1994-10-13 |
| EP0373744B1 (en) | 1994-06-22 |
| AU3827989A (en) | 1990-06-21 |
| DE68916387D1 (de) | 1994-07-28 |
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