[go: up one dir, main page]

ZA898376B - A method for the selective cleavage of fusion proteins - Google Patents

A method for the selective cleavage of fusion proteins

Info

Publication number
ZA898376B
ZA898376B ZA898376A ZA898376A ZA898376B ZA 898376 B ZA898376 B ZA 898376B ZA 898376 A ZA898376 A ZA 898376A ZA 898376 A ZA898376 A ZA 898376A ZA 898376 B ZA898376 B ZA 898376B
Authority
ZA
South Africa
Prior art keywords
fusion proteins
selective cleavage
insulins
human insulin
specific fusion
Prior art date
Application number
ZA898376A
Other languages
English (en)
Inventor
Laszlo Vertesy
Vertesy Laszlo
Klaus Sauber
Sauber Klaus
Eberhard Ehlers
Ehlers Eberhard
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA898376B publication Critical patent/ZA898376B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Welding Or Cutting Using Electron Beams (AREA)
  • Fuses (AREA)
  • Design And Manufacture Of Integrated Circuits (AREA)
  • Semiconductor Integrated Circuits (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA898376A 1988-11-03 1989-11-03 A method for the selective cleavage of fusion proteins ZA898376B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3837271A DE3837271A1 (de) 1988-11-03 1988-11-03 Verfahren zur selektiven spaltung von fusionsproteinen

Publications (1)

Publication Number Publication Date
ZA898376B true ZA898376B (en) 1990-08-29

Family

ID=6366365

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA898376A ZA898376B (en) 1988-11-03 1989-11-03 A method for the selective cleavage of fusion proteins

Country Status (17)

Country Link
EP (1) EP0367161B1 (xx)
JP (1) JP2877253B2 (xx)
KR (1) KR900007865A (xx)
AT (1) ATE139538T1 (xx)
AU (1) AU618420B2 (xx)
DE (2) DE3837271A1 (xx)
DK (1) DK546689A (xx)
ES (1) ES2088883T3 (xx)
FI (1) FI895183A7 (xx)
GR (1) GR3020297T3 (xx)
HU (1) HUT53677A (xx)
IL (1) IL92179A0 (xx)
NO (1) NO894362L (xx)
NZ (1) NZ231221A (xx)
PH (1) PH26508A (xx)
PT (1) PT92176B (xx)
ZA (1) ZA898376B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012048856A1 (en) 2010-10-12 2012-04-19 Glucometrix Pvs Gmbh Proinsulin with helper sequence
WO2012098009A1 (en) 2011-01-21 2012-07-26 Glucometrix Ag Chimeric polypeptide comprising a membrane protein and an insulin precursor
WO2013149729A2 (en) 2012-04-04 2013-10-10 Glucometrix Ag Proinsulin with enhanced helper sequence

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3418274A1 (de) * 1984-05-17 1985-11-21 Hoechst Ag, 6230 Frankfurt Signalpeptid fuer die exkretion von peptiden in streptomyceten
DK129385A (da) * 1985-03-22 1986-09-23 Novo Industri As Peptider og fremstilling deraf
DE3707150A1 (de) * 1987-03-06 1988-09-15 Hoechst Ag Tendamistat-derivate

Also Published As

Publication number Publication date
FI895183A0 (fi) 1989-11-01
NO894362L (no) 1990-05-04
PT92176B (pt) 1995-07-03
ES2088883T3 (es) 1996-10-01
DK546689A (da) 1990-05-04
NO894362D0 (no) 1989-11-02
IL92179A0 (en) 1990-07-26
FI895183A7 (fi) 1990-05-04
HU895664D0 (en) 1990-01-28
GR3020297T3 (en) 1996-09-30
ATE139538T1 (de) 1996-07-15
DE3837271A1 (de) 1990-05-10
EP0367161B1 (de) 1996-06-19
PT92176A (pt) 1990-05-31
JP2877253B2 (ja) 1999-03-31
NZ231221A (en) 1991-10-25
DK546689D0 (da) 1989-11-02
EP0367161A2 (de) 1990-05-09
DE58909692D1 (de) 1996-07-25
PH26508A (en) 1992-08-07
KR900007865A (ko) 1990-06-02
HUT53677A (en) 1990-11-28
JPH02195896A (ja) 1990-08-02
AU4397789A (en) 1990-05-10
EP0367161A3 (de) 1991-09-25
AU618420B2 (en) 1991-12-19

Similar Documents

Publication Publication Date Title
GB2197324B (en) Process for the production of a polypeptide
ATE123520T1 (de) Kex2-endoprotease und verfahren zu ihrer herstellung.
DE69532968D1 (de) Verfahren zur sekretion thrombopoitin polypeptide
SG49097A1 (en) Nucleotide sequences coding for a protein with urease activity
DE69112611D1 (de) Proteinhydrolysate.
ES8401777A1 (es) Procedimiento para producir un polipeptido.
DE3477810D1 (en) Polypeptide and protein products, and processes for their production and use
DK1137773T3 (da) Væsktfaktorhomolog ZVEGF3
DK164940C (da) Polypeptid med human-gamma-interferonaktivitet, genteknologisk fremgangsmaade til fremstilling deraf, hybrid-plasmider indeholdende en dna-sekvens, der koder for peptidet, vaertsorganismer indeholdende hybridplasmiderne, samt laegemidler, som indeholder polypeptidet
IL81018A (en) Fusion proteins comprising small fragments of human interleukin-2 as ballast,process for its preparation and genes,vectors and transformed host containing said fragments and used in the process
EP1449849A3 (en) Protease-resistant thrombomodulin analog
AU7017494A (en) Purified mammalian flt3 ligands and agonists and antagonists thereof
NZ231221A (en) A method for the selective cleavage of fusion proteins
ATE133711T1 (de) Produktion von cystinreste enthaltenden aktiven proteinen
AU590861B2 (en) New human lymphotoxin (TNF-beta) polypeptides their prepartion and use
BR1100940A (pt) Polipeptìdeos puros, sequências adn, molécula adn recombinada, célula hospedeira, processo de manipulação genética para produção de polipeptìdeo, e, uso de um polipeptìdeo
AU1321988A (en) The cloning of malaria-specific dna sequences: isolation of the gene for the 140 kd protein
EP0327360A3 (en) Novel polypeptides and dna encoding said polypeptides
AU2107892A (en) Process for producing peptide
KR950018453A (ko) 콜라게네이즈 인지부위를 가진 재조합 인간 성장 호르몬