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ZA888938B - Water soluble camptothecin analogs - Google Patents

Water soluble camptothecin analogs

Info

Publication number
ZA888938B
ZA888938B ZA888938A ZA888938A ZA888938B ZA 888938 B ZA888938 B ZA 888938B ZA 888938 A ZA888938 A ZA 888938A ZA 888938 A ZA888938 A ZA 888938A ZA 888938 B ZA888938 B ZA 888938B
Authority
ZA
South Africa
Prior art keywords
alkyl
hydrogen
water soluble
ch2nh2
formyl
Prior art date
Application number
ZA888938A
Other languages
English (en)
Inventor
Jeffrey Charles Boehm
Charles Boehm Jeffrey
Sidney Michael Hecht
Michael Hecht Sidney
Kenneth George Holden
George Holden Kenneth
Randall Keith Johnson
Keith Johnson Randall
William Dennis Kingsbury
Dennis Kingsbury William
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of ZA888938B publication Critical patent/ZA888938B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Semiconductor Lasers (AREA)
ZA888938A 1987-12-01 1988-11-29 Water soluble camptothecin analogs ZA888938B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12714887A 1987-12-01 1987-12-01

Publications (1)

Publication Number Publication Date
ZA888938B true ZA888938B (en) 1990-03-28

Family

ID=22428545

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA888938A ZA888938B (en) 1987-12-01 1988-11-29 Water soluble camptothecin analogs

Country Status (25)

Country Link
US (1) US5004758A (xx)
EP (1) EP0321122B1 (xx)
JP (1) JPH0633268B2 (xx)
KR (1) KR930009357B1 (xx)
CN (3) CN1027265C (xx)
AT (1) ATE143368T1 (xx)
AU (1) AU612735B2 (xx)
CA (1) CA1308102C (xx)
CY (1) CY2017A (xx)
DE (2) DE3855575T2 (xx)
DK (1) DK173034B1 (xx)
ES (1) ES2094721T3 (xx)
FI (1) FI89923C (xx)
GR (1) GR3021990T3 (xx)
HK (1) HK81097A (xx)
IE (1) IE74873B1 (xx)
IL (1) IL88517A (xx)
LU (2) LU90026I2 (xx)
MX (1) MX9203744A (xx)
NL (1) NL970017I2 (xx)
NO (2) NO170487C (xx)
NZ (1) NZ227124A (xx)
PT (1) PT89111B (xx)
SG (1) SG66254A1 (xx)
ZA (1) ZA888938B (xx)

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* Cited by examiner, † Cited by third party
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CN1034724A (zh) 1989-08-16
CN1087637A (zh) 1994-06-08
MX9203744A (es) 1992-09-01
NO885352D0 (no) 1988-11-30
NL970017I1 (nl) 1997-06-02
EP0321122B1 (en) 1996-09-25
FI885569L (fi) 1989-06-02
FI89923C (fi) 1993-12-10
GR3021990T3 (en) 1997-03-31
DE3855575D1 (de) 1996-10-31
FI885569A0 (fi) 1988-11-30
IE883576L (en) 1989-06-01
EP0321122A2 (en) 1989-06-21
NO885352L (no) 1989-06-02
ATE143368T1 (de) 1996-10-15
CA1308102C (en) 1992-09-29
CN1027265C (zh) 1995-01-04
CN1037574C (zh) 1998-03-04
DE3855575T2 (de) 1997-03-20
DK663688A (da) 1989-06-02
AU2639488A (en) 1989-06-01
LU90053I2 (fr) 1997-07-01
LU90026I2 (fr) 1997-04-22
NO170487B (no) 1992-07-13
PT89111B (pt) 1994-01-31
EP0321122A3 (en) 1990-12-27
CN1035380C (zh) 1997-07-09
IL88517A0 (en) 1989-06-30
HK81097A (en) 1997-06-20
IE74873B1 (en) 1997-08-13
NO1998003I1 (no) 1998-01-15
JPH01186893A (ja) 1989-07-26
AU612735B2 (en) 1991-07-18
DE19775017I2 (de) 2002-11-07
CN1083817A (zh) 1994-03-16
PT89111A (pt) 1989-12-29
ES2094721T3 (es) 1997-02-01
NZ227124A (en) 1991-12-23
KR930009357B1 (ko) 1993-09-28
IL88517A (en) 1994-10-07
DK173034B1 (da) 1999-11-29
FI89923B (fi) 1993-08-31
DK663688D0 (da) 1988-11-28
US5004758A (en) 1991-04-02
KR890009934A (ko) 1989-08-05
CY2017A (en) 1998-02-20
NL970017I2 (nl) 1997-09-01
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NO170487C (no) 1992-10-21
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