ZA200903160B - Sulfonyl-Phenyl-2H-[1,2,4]Oxodiazol-5-one Derivatives, Processes for their preparation and their use as pharmaceuticals - Google Patents
Sulfonyl-Phenyl-2H-[1,2,4]Oxodiazol-5-one Derivatives, Processes for their preparation and their use as pharmaceuticalsInfo
- Publication number
- ZA200903160B ZA200903160B ZA200903160A ZA200903160A ZA200903160B ZA 200903160 B ZA200903160 B ZA 200903160B ZA 200903160 A ZA200903160 A ZA 200903160A ZA 200903160 A ZA200903160 A ZA 200903160A ZA 200903160 B ZA200903160 B ZA 200903160B
- Authority
- ZA
- South Africa
- Prior art keywords
- oxodiazol
- pharmaceuticals
- sulfonyl
- phenyl
- derivatives
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Diabetes (AREA)
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- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
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- Dermatology (AREA)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06025880A EP1932843A1 (en) | 2006-12-14 | 2006-12-14 | Sulfonyl-phenyl-2H-(1,2,4) oxadiazole-5-one derivatives, processes for their preparation and their use as pharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200903160B true ZA200903160B (en) | 2010-10-27 |
Family
ID=37998695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200903160A ZA200903160B (en) | 2006-12-14 | 2009-05-07 | Sulfonyl-Phenyl-2H-[1,2,4]Oxodiazol-5-one Derivatives, Processes for their preparation and their use as pharmaceuticals |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8173674B2 (xx) |
| EP (2) | EP1932843A1 (xx) |
| JP (1) | JP2010512352A (xx) |
| KR (1) | KR20090087922A (xx) |
| CN (1) | CN101558064A (xx) |
| AR (1) | AR064299A1 (xx) |
| AU (1) | AU2007331805A1 (xx) |
| BR (1) | BRPI0720416A2 (xx) |
| CA (1) | CA2672347A1 (xx) |
| CL (1) | CL2007003614A1 (xx) |
| CO (1) | CO6210729A2 (xx) |
| CR (1) | CR10778A (xx) |
| EC (1) | ECSP099409A (xx) |
| MA (1) | MA30981B1 (xx) |
| MX (1) | MX2009005535A (xx) |
| NO (1) | NO20092293L (xx) |
| PE (1) | PE20081404A1 (xx) |
| RU (1) | RU2009126745A (xx) |
| SV (1) | SV2009003293A (xx) |
| TN (1) | TN2009000242A1 (xx) |
| TW (1) | TW200843749A (xx) |
| UY (1) | UY30783A1 (xx) |
| WO (1) | WO2008071311A1 (xx) |
| ZA (1) | ZA200903160B (xx) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010000353A1 (en) * | 2008-06-09 | 2010-01-07 | Sanofi-Aventis | Sulfonamides with heterocycle and oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals |
| EP2288604B1 (en) * | 2008-06-09 | 2014-01-08 | Sanofi | Annelated n-heterocyclic sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals |
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| US8859774B2 (en) | 2012-05-25 | 2014-10-14 | Corcept Therapeutics, Inc. | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators |
| EP3590517B1 (en) * | 2012-05-25 | 2021-03-17 | Corcept Therapeutics Incorporated | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators |
| US12226412B2 (en) | 2012-05-25 | 2025-02-18 | Corcept Therapeutics, Inc. | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators |
| US20190135798A1 (en) | 2015-11-02 | 2019-05-09 | Basf Se | Substituted Oxadiazoles for Combating Phytopathogenic Fungi |
| EP3165094A1 (en) | 2015-11-03 | 2017-05-10 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
| BR112018008288A2 (pt) | 2015-11-04 | 2018-10-30 | Basf Se | uso de compostos de fórmula, compostos de fórmula, mistura, composição agroquímica e método para combater fungos |
| WO2017085098A1 (en) | 2015-11-19 | 2017-05-26 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
| CA3003949A1 (en) | 2015-11-19 | 2017-05-26 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
| CN108884062A (zh) | 2016-04-11 | 2018-11-23 | 巴斯夫欧洲公司 | 用于防治植物病原性真菌的取代噁二唑类 |
| EP3468959A1 (en) | 2016-06-09 | 2019-04-17 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
| BR112018074559A2 (pt) | 2016-06-09 | 2019-03-12 | Basf Se | compostos, composição agroquímica, uso de compostos e método para combater fungos nocivos fitopatogênicos |
| BR112019011293A2 (pt) | 2016-12-19 | 2019-10-08 | Basf Se | compostos de fórmula i, intermediários, composição agroquímica, uso e método para combater fungos nocivos fitopatogênicos |
| EP3339297A1 (en) | 2016-12-20 | 2018-06-27 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
| MX2019011543A (es) | 2017-03-31 | 2019-12-16 | Corcept Therapeutics Inc | Moduladores del receptor de glucocorticoides para el tratamiento de cancer cervical. |
| WO2018219797A1 (en) | 2017-06-02 | 2018-12-06 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
| EP3642187A1 (en) | 2017-06-19 | 2020-04-29 | Basf Se | 2-[[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]aryloxy](thio)acetamides for combating phytopathogenic fungi |
| WO2019002158A1 (en) | 2017-06-30 | 2019-01-03 | Basf Se | SUBSTITUTED TRIFLUOROMETHYLOXADIAZOLES FOR THE CONTROL OF PHYTOPATHOGENIC FUNGI |
| US11076596B2 (en) | 2017-09-18 | 2021-08-03 | Basf Se | Substituted trifluoromethyloxadiazoles for combating phytopathogenic fungi |
| WO2019101511A1 (en) | 2017-11-23 | 2019-05-31 | Basf Se | Substituted trifluoromethyloxadiazoles for combating phytopathogenic fungi |
| WO2020132046A1 (en) | 2018-12-19 | 2020-06-25 | Corcept Therapeutics Incorporated | Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent |
| MX2021007322A (es) | 2018-12-19 | 2021-07-07 | Corcept Therapeutics Inc | Formulaciones farmaceuticas que contienen relacorilant, un compuesto de azadecalina fusionado con heteroaril-cetona. |
| US11234971B2 (en) | 2018-12-19 | 2022-02-01 | Corcept Therapeutics Incorporated | Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent |
| NZ778399A (en) | 2019-02-22 | 2024-11-29 | Corcept Therapeutics Inc | Therapeutic uses of relacorilant, a heteroaryl-ketone fused azadecalin glucocorticoid receptor modulator |
| CN115361866B (zh) * | 2020-03-31 | 2025-07-18 | 株式会社Lg化学 | 用于保护胰岛移植的组合物 |
| WO2022134033A1 (en) | 2020-12-25 | 2022-06-30 | Corcept Therapeutics Incorporated | Methods of preparing heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators |
| AU2023355849A1 (en) | 2022-10-06 | 2025-04-03 | Corcept Therapeutics Incorporated | Formulations of glucocorticoid receptor modulators |
| IL320512A (en) | 2022-10-28 | 2025-06-01 | Corcept Therapeutics Inc | Amyotrophic lateral sclerosis treatments using desocorilant |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5641796A (en) * | 1994-11-01 | 1997-06-24 | Eli Lilly And Company | Oral hypoglycemic agents |
| DE10222034A1 (de) * | 2002-05-17 | 2003-11-27 | Bayer Ag | Tetrahydroisochinolin-Derivate |
| DE10229777A1 (de) * | 2002-07-03 | 2004-01-29 | Bayer Ag | Indolin-Phenylsulfonamid-Derivate |
| JPWO2004080943A1 (ja) * | 2003-03-11 | 2006-06-08 | 小野薬品工業株式会社 | シンナミルアルコール誘導体化合物およびその化合物を有効成分として含有する薬剤 |
| US20060258683A1 (en) | 2003-04-07 | 2006-11-16 | Liu Kevin | Para-sulfonyl substituted phenyl compounds as modulators of ppars |
| DE10335449A1 (de) | 2003-08-02 | 2005-02-17 | Bayer Healthcare Ag | Bicyclische Indolinsulfonamid-Derivate |
| DE602004004631D1 (de) * | 2004-04-01 | 2007-03-22 | Sanofi Aventis Deutschland | Oxadiazolone, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Pharmazeutika |
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2006
- 2006-12-14 EP EP06025880A patent/EP1932843A1/en not_active Withdrawn
-
2007
- 2007-11-30 AU AU2007331805A patent/AU2007331805A1/en not_active Abandoned
- 2007-11-30 WO PCT/EP2007/010390 patent/WO2008071311A1/en not_active Ceased
- 2007-11-30 MX MX2009005535A patent/MX2009005535A/es not_active Application Discontinuation
- 2007-11-30 RU RU2009126745/04A patent/RU2009126745A/ru not_active Application Discontinuation
- 2007-11-30 BR BRPI0720416-7A patent/BRPI0720416A2/pt not_active IP Right Cessation
- 2007-11-30 JP JP2009540626A patent/JP2010512352A/ja not_active Abandoned
- 2007-11-30 EP EP07846915.2A patent/EP2102198B1/en active Active
- 2007-11-30 KR KR1020097012309A patent/KR20090087922A/ko not_active Withdrawn
- 2007-11-30 CA CA002672347A patent/CA2672347A1/en not_active Abandoned
- 2007-11-30 CN CNA2007800454445A patent/CN101558064A/zh active Pending
- 2007-12-12 UY UY30783A patent/UY30783A1/es not_active Application Discontinuation
- 2007-12-12 AR ARP070105563A patent/AR064299A1/es not_active Application Discontinuation
- 2007-12-12 CL CL200703614A patent/CL2007003614A1/es unknown
- 2007-12-12 PE PE2007001772A patent/PE20081404A1/es not_active Application Discontinuation
- 2007-12-12 TW TW096147333A patent/TW200843749A/zh unknown
-
2009
- 2009-05-07 ZA ZA200903160A patent/ZA200903160B/xx unknown
- 2009-05-07 CR CR10778A patent/CR10778A/es not_active Application Discontinuation
- 2009-06-05 CO CO09058528A patent/CO6210729A2/es not_active Application Discontinuation
- 2009-06-09 US US12/480,974 patent/US8173674B2/en not_active Expired - Fee Related
- 2009-06-10 MA MA31971A patent/MA30981B1/fr unknown
- 2009-06-10 SV SV2009003293A patent/SV2009003293A/es unknown
- 2009-06-12 TN TNP2009000242A patent/TN2009000242A1/fr unknown
- 2009-06-12 EC EC2009009409A patent/ECSP099409A/es unknown
- 2009-06-15 NO NO20092293A patent/NO20092293L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20090298871A1 (en) | 2009-12-03 |
| RU2009126745A (ru) | 2011-01-20 |
| SV2009003293A (es) | 2009-10-27 |
| AU2007331805A1 (en) | 2008-06-19 |
| NO20092293L (no) | 2009-09-08 |
| CA2672347A1 (en) | 2008-06-19 |
| AR064299A1 (es) | 2009-03-25 |
| BRPI0720416A2 (pt) | 2013-12-31 |
| US8173674B2 (en) | 2012-05-08 |
| PE20081404A1 (es) | 2008-11-04 |
| CO6210729A2 (es) | 2010-10-20 |
| MA30981B1 (fr) | 2009-12-01 |
| TW200843749A (en) | 2008-11-16 |
| MX2009005535A (es) | 2009-06-05 |
| UY30783A1 (es) | 2008-07-31 |
| EP2102198A1 (en) | 2009-09-23 |
| ECSP099409A (es) | 2009-07-31 |
| EP2102198B1 (en) | 2015-02-25 |
| WO2008071311A1 (en) | 2008-06-19 |
| EP1932843A1 (en) | 2008-06-18 |
| CR10778A (es) | 2009-06-24 |
| TN2009000242A1 (en) | 2010-10-18 |
| JP2010512352A (ja) | 2010-04-22 |
| KR20090087922A (ko) | 2009-08-18 |
| CN101558064A (zh) | 2009-10-14 |
| CL2007003614A1 (es) | 2008-06-20 |
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