ZA200902278B - Aminomethyl-4-imidazoles - Google Patents

Aminomethyl-4-imidazoles

Info

Publication number: ZA200902278B
Authority: ZA; South Africa
Prior art keywords: imidazoles; aminomethyl
Prior art date: 2006-10-19

Application number

ZA200902278A

Other languages

English (en)

Inventor

Guido Galley

Annick Goergler

Zbinden Katrin Groebke

Roger Norcross

Henri Stalder

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-10-19

Filing date

2009-04-01

Publication date

2010-03-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38876376&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200902278(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-04-01 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2010-03-31 Publication of ZA200902278B publication Critical patent/ZA200902278B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Psychiatry (AREA)
Hematology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Child & Adolescent Psychology (AREA)
Urology & Nephrology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Addiction (AREA)
Vascular Medicine (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

ZA200902278A 2006-10-19 2009-04-01 Aminomethyl-4-imidazoles ZA200902278B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP06122586		2006-10-19

Publications (1)

Publication Number	Publication Date
ZA200902278B true ZA200902278B (en)	2010-03-31

Family

ID=38876376

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200902278A ZA200902278B (en)	2006-10-19	2009-04-01	Aminomethyl-4-imidazoles

Country Status (20)

Country	Link
US (1)	US8586617B2 (xx)
EP (1)	EP2076497B1 (xx)
JP (2)	JP5335681B2 (xx)
KR (1)	KR101176699B1 (xx)
CN (1)	CN101528710B (xx)
AR (1)	AR063327A1 (xx)
AT (1)	ATE546437T1 (xx)
AU (1)	AU2007312390B2 (xx)
BR (1)	BRPI0717939A2 (xx)
CA (1)	CA2666762C (xx)
CL (1)	CL2007002971A1 (xx)
ES (1)	ES2381589T3 (xx)
IL (1)	IL197877A (xx)
MX (1)	MX2009003801A (xx)
NO (1)	NO20091478L (xx)
PE (1)	PE20080889A1 (xx)
RU (1)	RU2009112496A (xx)
TW (1)	TW200833685A (xx)
WO (1)	WO2008046757A1 (xx)
ZA (1)	ZA200902278B (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2076497B1 (en) *	2006-10-19	2012-02-22	F. Hoffmann-La Roche AG	Aminomethyl-4-imidazoles
CA2666489C (en) *	2006-10-19	2012-10-02	F. Hoffmann-La Roche Ag	Imidazolone and imidazolidinone derivatives as 11b-hsd1 inhibitors for diabetes
DK2252594T3 (en)	2008-01-22	2015-11-23	Dow Agrosciences Llc	4-amino-5-fluoro-pyrimidine derivatives as fungicides
US8242153B2 (en) *	2008-07-24	2012-08-14	Hoffmann-La Roche Inc.	4,5-dihydro-oxazol-2YL derivatives
MX2011001091A (es) *	2008-08-01	2011-03-15	Dow Agrosciences Llc	Uso de 5-fluorocitosina como un fungicida.
US8933227B2 (en)	2009-08-14	2015-01-13	Boehringer Ingelheim International Gmbh	Selective synthesis of functionalized pyrimidines
WO2011018517A1 (en)	2009-08-14	2011-02-17	Boehringer Ingelheim International Gmbh	Regioselective preparation of 2-amino-5-trifluoromethylpyrimidine derivatives
US8354441B2 (en) *	2009-11-11	2013-01-15	Hoffmann-La Roche Inc.	Oxazoline derivatives
US9452980B2 (en)	2009-12-22	2016-09-27	Hoffmann-La Roche Inc.	Substituted benzamides
WO2011150156A2 (en)	2010-05-26	2011-12-01	Sunovion Pharmaceuticals Inc.	Heteroaryl compounds and methods of use thereof
KR101651208B1 (ko)	2014-02-19	2016-08-26	충북대학교 산학협력단	클로로겐산 유도체 화합물 및 이를 유효성분으로 포함하는 항염증 및 피부미백용 조성물
CA2991174A1 (en) *	2015-07-01	2017-01-05	Lifesci Pharmaceuticals, Inc.	Therapeutic inhibitory compounds
CN107531613B (zh) *	2016-02-03	2021-02-05	华东理工大学	苯并脂肪环取代烷基胺类化合物及其用途
HRP20201405T1 (hr)	2016-03-17	2020-11-27	F. Hoffmann - La Roche Ag	Derivat 5-etil-4-metil-pirazol-3-karboksamida, koji djeluje kao agonist taar-a
US10981899B2 (en)	2016-04-28	2021-04-20	Cornell University	Inhibitors of soluble adenylyl cyclase
US20190201410A1 (en) *	2016-06-02	2019-07-04	Purdue Pharma L.P.	Trace amine associated receptor 1 agonists and partial agonists for pain treatment
WO2023033680A1 (en)	2021-09-01	2023-03-09	Limited Liability Company «Excellena Research And Development» (Llc «Excellena»)	Substituted 2,3,4,5-tetrahydrobenzo[ f][1,4]oxazepines as modulators of trace amine-associated receptor 1 (taar1)
WO2023033681A1 (en)	2021-09-01	2023-03-09	Limited Liability Company «Excellena Research And Development» (Llc «Excellena»)	Substituted 2-(5-aryl-4 h-1,2,4-triazol-3-yl)ethanamines as modulators of trace amine-associated receptor 1 (taar1)
WO2023033679A1 (en)	2021-09-01	2023-03-09	Limited Liability Company «Excellena Research And Development» (Llc «Excellena»)	(azacycloalkyl)methoxy-substituted benzamides as modulators of trace amine-associated receptor 1 (taar1)

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2731471A (en)		1956-01-17		Nxg hi
FR6551E (fr)	1905-07-27	1906-12-17	Carlo Chiesa	Séchoir à tambour rotatif, démontable et transportable, et fonctionnant à ciel ouvert, pour cocons, céréales, etc.
US2161938A (en)	1934-07-31	1939-06-13	Soc Of Chemical Ind	Imidazolines
US2457047A (en)	1946-02-13	1948-12-21	Monsanto Chemicals	2-(2'-thenyl)-4, 5-dihydroimidazoles and process for making the same
US2778836A (en)	1954-04-02	1957-01-22	Union Chimique Belge Sa	Substituted 2-methyl-delta2 imidazolines
US2744910A (en)	1955-06-27	1956-05-08	Bristol Lab Inc	2-(ortho-benzylbenzyl)-imidazoline and acid addition salts
US2744909A (en)	1955-06-27	1956-05-08	Bristol Lab Inc	2-(ortho-phenylbenzyl) imidazoline and acid addition salts
US2919274A (en)	1957-09-17	1959-12-29	Sahyun Melville	Amidines
GB877306A (en)	1958-04-21	1961-09-13	Pfizer & Co C	Halogenated derivatives of tetrahydro-1-naphthyl cyclic amidines
DE1121054B (de)	1960-11-23	1962-01-04	Merck Ag E	Verfahren zur Herstellung eines neuen Imidazolinderivates und dessen Saeureadditionssalzen
US3202660A (en)	1961-10-09	1965-08-24	Boehringer Sohn Ingelheim	Process for the preparation of 3-arylamino-1, 3-diazacycloalkenes
DE1150180B (de)	1962-04-12	1963-06-12	Merck Ag E	Mittel zur Vorbehandlung der Haut fuer die Rasur
ES323985A1 (es)	1966-02-26	1966-12-16	Blade Pique Juan	Procedimiento para la obtenciën de derivados del imidazol
US3377247A (en)	1967-04-28	1968-04-09	Dow Chemical Co	Antidepressant method
US3586695A (en)	1968-01-26	1971-06-22	Dow Chemical Co	Substituted imidazolinyl indoles
BE754820R (fr)	1969-08-13	1971-02-15	Schering Ag	Nouveaux derives de pyrimidine, leurs procedes de preparation et leurs
US3818094A (en)	1969-08-28	1974-06-18	Boehringer Sohn Ingelheim	Hypotensive pharmaceutical compositions containing certain 2-anilino-1,3-diazacyclopentenes-(2)
US3622579A (en)	1969-08-28	1971-11-23	Boehringer Sohn Ingelheim	Derivatives of 2-anilino-1,3-diazacyclopentene-(2)
US3660423A (en)	1970-02-13	1972-05-02	Dow Chemical Co	2-(substituted benzyl)methyl-2-imidazolines
GB1333471A (en)	1971-01-27	1973-10-10	Labaz	Imidazoline derivatives and process for preparing the same
US4125620A (en)	1974-10-01	1978-11-14	Boehringer Ingelheim Gmbh	2-[(2',6'-Disubstituted-phenyl)-imino]-imidazolidines and salts thereof
US3992403A (en)	1975-05-30	1976-11-16	Schering Corporation	2-Imidazolines and their use as hypoglycemic agents
GB1538097A (en)	1976-01-26	1979-01-10	Lafon Labor	Substituted phenyl-amidines
US4323570A (en)	1978-11-15	1982-04-06	Beiersdorf Aktiengesellschaft	Substituted aminopyrimidines
AU518569B2 (en)	1979-08-07	1981-10-08	Farmos-Yhtyma Oy	4-benzyl- and 4-benzoyl imidazole derivatives
GB2110663B (en) *	1981-12-04	1985-08-07	Farmos Group Ltd	Imidazole derivatives
US4505918A (en) *	1982-11-08	1985-03-19	Merck & Co., Inc.	4-[2-Pyridinylthio(oxy or amino)methyl]-1H-imidazoles and derivatives
US4540705A (en)	1983-03-14	1985-09-10	Sterling Drug Inc.	Antidepressant imidazolines and related compounds
DE3583900D1 (de)	1984-06-06	1991-10-02	Abbott Lab	Adrenergische verbindungen.
US4665095A (en)	1985-12-11	1987-05-12	Abbott Laboratories	Use of 2-[(3,5-dihalo-4-aminobenzyl)]imidazolines to stimulate alpha-1 adrenergic receptors and to treat nasal congestion
JPH0774205B2 (ja) *	1986-12-04	1995-08-09	三井石油化学工業株式会社	新規イミダゾ−ル誘導体
GB2215206B (en)	1988-02-29	1991-07-03	Farmos Oy	4-substituted imidazole derivatives useful in perioperative care
FI894911A0 (fi)	1989-10-17	1989-10-17	Farmos Oy	En terapeutiskt vaerdefull foerening.
FR2692893B1 (fr) *	1992-06-24	1994-09-02	Sanofi Elf	Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
AU707843B2 (en)	1993-10-13	1999-07-22	Concordia Pharmaceuticals Inc.	Extended release clonidine formulation
GB9425211D0 (en)	1994-12-14	1995-02-15	Ucb Sa	Substituted 1H-imidazoles
US5610174A (en)	1995-06-02	1997-03-11	Synaptic Pharmaceutical Corporation	Use of α1A -selective adrenoceptor agonists for the treatment of urinary incontinence
GB9520150D0 (en)	1995-10-03	1995-12-06	Orion Yhtymae Oy	New imidazole derivatives
DE19607487C2 (de)	1996-02-28	1998-09-10	Byk Gulden Lomberg Chem Fab	Verwendung von alpha1-Adrenoceptor-Antagonisten
US5969137A (en)	1996-09-19	1999-10-19	Virginia Commonwealth University	Benzylamidine derivatives with serotonin receptor binding activity
CA2229123A1 (en)	1997-02-11	1998-08-11	Mitchell Irvin Steinberg	Pharmaceutical agents
US5866579A (en)	1997-04-11	1999-02-02	Synaptic Pharmaceutical Corporation	Imidazole and imidazoline derivatives and uses thereof
US6841684B2 (en)	1997-12-04	2005-01-11	Allergan, Inc.	Imidiazoles having reduced side effects
DE69823868T2 (de)	1997-12-04	2005-04-21	Allergan Inc	Substituierte imidazole derivate mit agonistischähnlicher wirkung auf die alpha 2b oder 2b/2c adrenergischen rezeptoren
EP0924209B1 (en)	1997-12-19	2003-05-02	Eli Lilly And Company	Hypoglycemic imidazoline compounds
ATE293102T1 (de)	1998-04-23	2005-04-15	Takeda Pharmaceutical	Naphthalene derivate ,ihre herstellung und verwendung
ES2150378B1 (es)	1998-08-07	2001-07-01	Esteve Labor Dr	Empleo de derivados de aril(o heteroaril)azolilcarbinoles en la elaboracion de un medicamento para el tratamiento de los trastornos mediados por un exceso de substancia p.
CA2246027A1 (en)	1998-08-27	2000-02-27	Virginia Commonwealth University	Benzylamidine derivatives with serotonin receptor binding activity
PE20010781A1 (es)	1999-10-22	2001-08-08	Takeda Chemical Industries Ltd	Compuestos 1-(1h-imidazol-4-il)-1-(naftil-2-sustituido)etanol, su produccion y utilizacion
FI20000073A0 (fi)	2000-01-14	2000-01-14	Orion Yhtymae Oy	Uusia imidatsolijohdannaisia
JP2001302643A (ja)	2000-04-21	2001-10-31	Suntory Ltd	環状アミジン化合物
AU2001292617A1 (en)	2000-09-12	2002-03-26	Oregon Health And Science University	Mammalian receptor genes and uses
IL155436A0 (en)	2000-11-14	2003-11-23	Hoffmann La Roche	Substituted 2-phenylaminoimidazoline phenyl ketone derivatives as ip antagonists
IL147921A0 (en)	2002-01-31	2002-08-14	Abdulrazik Mohammad	A method for treating central nervous system disorders by ocular dosing
TW200930291A (en)	2002-04-29	2009-07-16	Bayer Cropscience Ag	Pesticidal heterocycles
KR100492252B1 (ko)	2002-08-09	2005-05-30	한국화학연구원	이미다졸을 포함하는 이차아민으로 치환된 벤조피란유도체 및 그의 제조방법
BR0313743A (pt)	2002-08-23	2005-07-05	Chiron Corp	Benzimidazol quinolinonas e usos destas
JP4881558B2 (ja)	2002-09-04	2012-02-22	シェーリングコーポレイション	サイクリン依存性キナーゼインヒビターとしてのピラゾロピリミジン
AU2003278249B8 (en)	2002-09-05	2010-11-18	Aventis Pharma S.A.	Novel aminoindazole derivatives as medicines and pharmaceutical compositions containing same
JP2008540441A (ja) *	2005-05-03	2008-11-20	バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト	殺虫性の置換されたアミノアルキル複素環式及びヘテロアリール誘導体
EP1888512A2 (en) *	2005-06-06	2008-02-20	Smithkline Beecham Corporation	Chemical compounds
AU2006283104A1 (en)	2005-08-25	2007-03-01	Pharmacopeia, Inc.	Imidazole derivatives as functionally selective alpha2C adrenoreceptor agonists
RU2442779C2 (ru)	2005-12-01	2012-02-20	Ф. Хоффманн-Ля Рош Аг	Производные 2,4,5-трифенилимидазолина как ингибиторы взаимодействия между белками p53 и mdm2, предназначенные для применения в качестве противораковых средств
NL2000439C2 (nl)	2006-01-20	2009-03-16	Quark Biotech	Therapeutische toepassingen van inhibitoren van RTP801.
ES2338716T3 (es) *	2006-01-27	2010-05-11	F.Hoffmann-La Roche Ag	Uso de derivados de 4-imidazol para trastornos del snc.
CA2666489C (en)	2006-10-19	2012-10-02	F. Hoffmann-La Roche Ag	Imidazolone and imidazolidinone derivatives as 11b-hsd1 inhibitors for diabetes
EP2076497B1 (en)	2006-10-19	2012-02-22	F. Hoffmann-La Roche AG	Aminomethyl-4-imidazoles
WO2008046756A1 (en)	2006-10-19	2008-04-24	F. Hoffmann-La Roche Ag	Aminomethyl-2-imidazoles with affinity with the trace amine associated receptors
CL2007002994A1 (es)	2006-10-19	2008-02-08	Wyeth Corp	Compuestos derivados heterociclicos que contienen sulfamoilo, inhibidores de hsp90; composicion farmaceutica; y uso para el tratamiento del cancer, tal como cancer de mama, de colon y prostata, entre otros.

2007
- 2007-10-09 EP EP07821039A patent/EP2076497B1/en not_active Not-in-force
- 2007-10-09 ES ES07821039T patent/ES2381589T3/es active Active
- 2007-10-09 AU AU2007312390A patent/AU2007312390B2/en not_active Ceased
- 2007-10-09 CN CN2007800388091A patent/CN101528710B/zh not_active Expired - Fee Related
- 2007-10-09 MX MX2009003801A patent/MX2009003801A/es active IP Right Grant
- 2007-10-09 WO PCT/EP2007/060666 patent/WO2008046757A1/en not_active Ceased
- 2007-10-09 AT AT07821039T patent/ATE546437T1/de active
- 2007-10-09 KR KR1020097007948A patent/KR101176699B1/ko not_active Expired - Fee Related
- 2007-10-09 JP JP2009532767A patent/JP5335681B2/ja not_active Expired - Fee Related
- 2007-10-09 RU RU2009112496/04A patent/RU2009112496A/ru not_active Application Discontinuation
- 2007-10-09 CA CA2666762A patent/CA2666762C/en not_active Expired - Fee Related
- 2007-10-09 BR BRPI0717939-1A2A patent/BRPI0717939A2/pt not_active IP Right Cessation
- 2007-10-15 US US11/872,203 patent/US8586617B2/en not_active Expired - Fee Related
- 2007-10-17 PE PE2007001403A patent/PE20080889A1/es not_active Application Discontinuation
- 2007-10-17 TW TW096138932A patent/TW200833685A/zh unknown
- 2007-10-17 CL CL200702971A patent/CL2007002971A1/es unknown
- 2007-10-17 AR ARP070104590A patent/AR063327A1/es unknown
2009
- 2009-03-26 IL IL197877A patent/IL197877A/en not_active IP Right Cessation
- 2009-04-01 ZA ZA200902278A patent/ZA200902278B/xx unknown
- 2009-04-17 NO NO20091478A patent/NO20091478L/no not_active Application Discontinuation
2013
- 2013-05-02 JP JP2013096834A patent/JP5567177B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
MX2009003801A (es)	2009-04-22
AU2007312390B2 (en)	2013-03-28
CL2007002971A1 (es)	2008-05-30
CA2666762C (en)	2014-12-30
IL197877A0 (en)	2009-12-24
AR063327A1 (es)	2009-01-21
TW200833685A (en)	2008-08-16
NO20091478L (no)	2009-05-05
RU2009112496A (ru)	2010-11-27
CN101528710A (zh)	2009-09-09
IL197877A (en)	2015-07-30
KR20090055035A (ko)	2009-06-01
WO2008046757A1 (en)	2008-04-24
US20080119535A1 (en)	2008-05-22
ES2381589T3 (es)	2012-05-29
JP5335681B2 (ja)	2013-11-06
EP2076497A1 (en)	2009-07-08
ATE546437T1 (de)	2012-03-15
BRPI0717939A2 (pt)	2013-12-03
CN101528710B (zh)	2012-11-07
JP2010506875A (ja)	2010-03-04
PE20080889A1 (es)	2008-06-27
AU2007312390A1 (en)	2008-04-24
KR101176699B1 (ko)	2012-08-23
JP2013173779A (ja)	2013-09-05
JP5567177B2 (ja)	2014-08-06
CA2666762A1 (en)	2008-04-24
US8586617B2 (en)	2013-11-19
EP2076497B1 (en)	2012-02-22

Publication	Publication Date	Title
EP2078282A4 (en)	2011-09-28	ELECTRONIC COUPONS
DE602007008085D1 (en)	2010-09-09	Dihydropyrazolopyrimidinonderivate
DE602007014031D1 (en)	2011-06-01	Luftreifensatz
DE602007002070D1 (en)	2009-10-01	2-pyrazincarboxamidderivate
DE602007001601D1 (en)	2009-08-27	Glasuntersuchung
EP1983992A4 (en)	2010-08-18	2-IMINO-BENZIMIDAZOLES
IL197877A0 (en)	2009-12-24	Aminomethyl-4-imidazoles
DE602007006989D1 (en)	2010-07-15	Spiropiperidinderivate
EP2084019A4 (en)	2012-06-27	PAINT SCRAPER
AP2008004724A0 (en)	2008-12-31	Substituted1-yl)-azolin-2-aryl-1-hetaryl-ethane
DE602007011622D1 (en)	2011-02-10	Penem-prodrugs
EP2024567A4 (en)	2011-08-24	TONTAPETE
EP2007388A4 (en)	2009-11-25	OPIOPATHIEN
DK1989111T3 (en)	2020-02-10	Satellitluftbremseapparat
EP1974618A4 (en)	2013-05-01	UNDERWEAR
DE502007001126D1 (en)	2009-09-03	Eiten
GB0602258D0 (en)	2006-03-15	Privyphone
GB0601584D0 (en)	2006-03-08	Cosyhold headscarf
AU3514P (en)	2008-04-30	ARCBENT Arctotis fastuosa
AU4914P (en)	2014-09-03	CalflatGL Calothamnus quadrifidus
GB0600344D0 (en)	2006-02-15	Cuffclamp
GB0602307D0 (en)	2006-03-15	Suction-deflater
AU312610S (en)	2007-01-29	Jewellery - pendant
AU312609S (en)	2007-01-29	Jewellery - pendant
AU311794S (en)	2006-12-06	Pouff