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ZA200907643B - Processes for preparing (r)-2-methylpyrrolidine and (s)-2-methylpyrrolidine and tartrate salts thereof - Google Patents

Processes for preparing (r)-2-methylpyrrolidine and (s)-2-methylpyrrolidine and tartrate salts thereof

Info

Publication number
ZA200907643B
ZA200907643B ZA2009/07643A ZA200907643A ZA200907643B ZA 200907643 B ZA200907643 B ZA 200907643B ZA 2009/07643 A ZA2009/07643 A ZA 2009/07643A ZA 200907643 A ZA200907643 A ZA 200907643A ZA 200907643 B ZA200907643 B ZA 200907643B
Authority
ZA
South Africa
Prior art keywords
methylpyrrolidine
preparing
processes
tartrate salts
tartrate
Prior art date
Application number
ZA2009/07643A
Other languages
English (en)
Inventor
Michael Christie
Joseph James Petraitis
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of ZA200907643B publication Critical patent/ZA200907643B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
ZA2009/07643A 2007-05-03 2009-10-30 Processes for preparing (r)-2-methylpyrrolidine and (s)-2-methylpyrrolidine and tartrate salts thereof ZA200907643B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92735607P 2007-05-03 2007-05-03
PCT/US2008/005702 WO2008137087A1 (fr) 2007-05-03 2008-05-02 Procédé de préparation de la (r)-2-méthylpyrrolidine, de la (s)-2-methylpyrrolidine et de leurs tartrates

Publications (1)

Publication Number Publication Date
ZA200907643B true ZA200907643B (en) 2014-03-26

Family

ID=39688886

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2009/07643A ZA200907643B (en) 2007-05-03 2009-10-30 Processes for preparing (r)-2-methylpyrrolidine and (s)-2-methylpyrrolidine and tartrate salts thereof

Country Status (14)

Country Link
EP (1) EP2152669A1 (fr)
JP (1) JP5698887B2 (fr)
KR (1) KR20100017565A (fr)
CN (1) CN101679237A (fr)
AU (1) AU2008248168B2 (fr)
BR (1) BRPI0810330A2 (fr)
CA (1) CA2686033A1 (fr)
EA (1) EA019031B1 (fr)
IL (1) IL201627A (fr)
MX (1) MX2009011787A (fr)
NZ (1) NZ580948A (fr)
UA (1) UA99913C2 (fr)
WO (1) WO2008137087A1 (fr)
ZA (1) ZA200907643B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5335675B2 (ja) 2006-07-25 2013-11-06 セファロン、インク． ピリジジノン誘導体
US8383657B2 (en) 2007-12-21 2013-02-26 Abbott Laboratories Thiazolylidine urea and amide derivatives and methods of use thereof
EP2252593B1 (fr) * 2008-01-30 2014-04-23 Cephalon, Inc. Dérivés de pyridazine substitués à activité antagoniste des récepteurs h3 de l'histamine
US10259794B2 (en) * 2014-12-23 2019-04-16 Cephalon, Inc. Methods for preparing fused bicyclic 2, 4-diaminopyrimidine derivatives
TW202026280A (zh) * 2018-09-07 2020-07-16 法商賽諾菲公司 6-(2,4-二氯苯基)-5-[4-[(3s)-1-(3-氟丙基)吡咯啶-3-基]氧基苯基]-8,9-二氫-7h-苯並[7]輪烯-2-甲酸甲酯的鹽及其製備方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3329974A1 (de) 1983-08-19 1985-02-28 Bayer Ag, 5090 Leverkusen Herstellung von hydrierten nitrilkautschuken
DE3433392A1 (de) 1984-09-12 1986-03-20 Bayer Ag, 5090 Leverkusen Hydrierung nitrilgruppenhaltiger ungesaettigter polymerer
FR2714849B1 (fr) 1994-01-13 1996-04-05 Inst Francais Du Petrole Procédé de préparation d'un catalyseur d'hydrogénation soluble en phase liquide organique.
DE4403479A1 (de) 1994-02-04 1995-08-10 Basf Ag Verfahren zur Herstellung von Hydroxylammoniumsalzen
WO2004024707A2 (fr) * 2002-09-16 2004-03-25 Abbott Laboratories Procede permettant de preparer des benzofuranes a substitution amine
US7153889B2 (en) 2002-11-12 2006-12-26 Abbott Laboratories Bicyclic-substituted amines as histamine-3 receptor ligands
US8110519B2 (en) 2004-03-08 2012-02-07 Japan Science & Technology Agency Polymer-supported metal cluster composition
US7145005B2 (en) 2004-05-12 2006-12-05 Abbott Laboratories 2-(6-{2-[(2R)-2-Methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation
DK1755593T3 (da) 2004-06-02 2008-05-19 Hoffmann La Roche Naphtalenderivater der er nyttige som histamin-3-receptorligander
WO2006059778A1 (fr) 2004-12-01 2006-06-08 Banyu Pharmaceutical Co., Ltd. Dérivé substitué de pyridone
WO2006066197A1 (fr) 2004-12-17 2006-06-22 Janssen Pharmaceutica, N.V. Composes de tetrahydroisoquinoline pour le traitement de troubles du systeme nerveux central
CN101107231A (zh) 2005-01-21 2008-01-16 先灵公司 用作组胺h3拮抗剂的咪唑和苯并咪唑衍生物
EP1866293A1 (fr) 2005-03-31 2007-12-19 UCB Pharma, S.A. Composes comprenant un groupe fonctionnel d'oxazole ou de thiazole, processus de fabrication et leur utilisation
GB0514812D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds
WO2007048595A1 (fr) 2005-10-27 2007-05-03 Ucb Pharma, S.A. Composés comprenant un lactame ou un groupement dérivé de lactame, procedes de fabrication de ceux-ci, et leurs utilisations
US7897634B2 (en) 2006-02-09 2011-03-01 Athersys, Inc. Pyrazoles for the treatment of obesity and other CNS disorders
WO2007099423A1 (fr) 2006-03-02 2007-09-07 Pfizer Products Inc. Dérivés de 1-pyrrolidine indane en tant qu'antagonistes du récepteur d'histamine 3
CA2643055A1 (fr) 2006-03-13 2007-09-20 Pfizer Products Inc. Tetralines en tant qu'antagonistes du recepteur h-3
EP2035372A1 (fr) 2006-06-29 2009-03-18 Arena Pharmaceuticals, Inc. Modulateurs du récepteur h3 de l'histamine utiles dans le traitement de troubles liés audit récepteur
JP5335675B2 (ja) 2006-07-25 2013-11-06 セファロン、インク． ピリジジノン誘導体

Also Published As

Publication number Publication date
IL201627A (en) 2014-06-30
CA2686033A1 (fr) 2008-11-13
EA200971019A1 (ru) 2010-04-30
NZ580948A (en) 2011-04-29
WO2008137087A1 (fr) 2008-11-13
UA99913C2 (ru) 2012-10-25
KR20100017565A (ko) 2010-02-16
EP2152669A1 (fr) 2010-02-17
EA019031B1 (ru) 2013-12-30
CN101679237A (zh) 2010-03-24
IL201627A0 (en) 2010-05-31
BRPI0810330A2 (pt) 2014-10-14
AU2008248168B2 (en) 2013-03-21
JP5698887B2 (ja) 2015-04-08
MX2009011787A (es) 2009-11-13
AU2008248168A1 (en) 2008-11-13
JP2010526142A (ja) 2010-07-29

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