ZA200809111B - Substituted carboxamides - Google Patents

Substituted carboxamides

Info

Publication number: ZA200809111B
Authority: ZA; South Africa
Prior art keywords: substituted carboxamides; substituted; carboxamides; formula; pharmaceutically acceptable
Prior art date: 2006-06-08

Application number

ZA200809111A

Other languages

English (en)

Inventor

Ryan Thomas Backer

Matthew Joseph Fisher

Steven Lee Kuklish

Sean Patrick Hollinshead

Edward C R Smith

Kumiko Takeuchi

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-06-08

Filing date

2008-10-23

Publication date

2009-12-30

2008-10-23 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2009-12-30 Publication of ZA200809111B publication Critical patent/ZA200809111B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Immunology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Thiazole And Isothizaole Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ZA200809111A 2006-06-08 2008-10-23 Substituted carboxamides ZA200809111B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US81183906P	2006-06-08	2006-06-08

Publications (1)

Publication Number	Publication Date
ZA200809111B true ZA200809111B (en)	2009-12-30

Family

ID=39673278

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200809111A ZA200809111B (en)	2006-06-08	2008-10-23	Substituted carboxamides

Country Status (30)

Country	Link
US (1)	US7960419B2 (xx)
EP (1)	EP2076502B1 (xx)
JP (1)	JP5108878B2 (xx)
KR (1)	KR101051559B1 (xx)
CN (1)	CN101466691B (xx)
AT (1)	ATE509921T1 (xx)
AU (1)	AU2007347428B2 (xx)
BR (1)	BRPI0712862A2 (xx)
CA (1)	CA2652074C (xx)
CR (1)	CR10410A (xx)
CY (1)	CY1111588T1 (xx)
DK (1)	DK2076502T3 (xx)
EA (1)	EA014233B1 (xx)
EC (1)	ECSP088939A (xx)
ES (1)	ES2362949T3 (xx)
HR (1)	HRP20110436T1 (xx)
IL (1)	IL195632A (xx)
MA (1)	MA30620B1 (xx)
MX (1)	MX2008015485A (xx)
MY (1)	MY148084A (xx)
NO (1)	NO341474B1 (xx)
NZ (1)	NZ573352A (xx)
PL (1)	PL2076502T3 (xx)
PT (1)	PT2076502E (xx)
RS (1)	RS51818B (xx)
SI (1)	SI2076502T1 (xx)
TN (1)	TNSN08506A1 (xx)
UA (1)	UA95480C2 (xx)
WO (1)	WO2008103185A2 (xx)
ZA (1)	ZA200809111B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0804685D0 (en)	2008-03-13	2008-04-16	Univ Edinburgh	Therapeutic compounds and their use
AR070986A1 (es)	2008-04-04	2010-05-19	Lilly Co Eli	Compuesto de 3-indazoil-4 -piridilisotiazoles, composicion farmaceutica que lo comprende y su uso para la manufactura de un medicamento util para tratar la ansiedad
EP2443113A1 (en) *	2009-06-15	2012-04-25	The University Of Edinburgh	Amido-isothiazole compounds and their use as inhibitors of 11beta-hsd1 for the treatment of metabolic syndrome and related disorders
US8642621B2 (en)	2009-09-16	2014-02-04	The University Of Edinburgh	(4-phenyl-piperidin-1-yl)-[5-(1H-pyrazol-4-yl)-thiophen-3-yl]-methanone compounds and their use
CN102947295B (zh)	2010-04-29	2016-01-20	爱丁堡大学	作为11β-HSD1抑制剂的3,3-二取代的-(8-氮杂双环[3.2.1]辛烷-8-基)-[5-(1H-吡唑-4基)-噻吩-3-基]-甲酮
MY173812A (en)	2012-11-13	2020-02-24	Nissan Chemical Ind Ltd	2-pyridone compound
CN109963858A (zh)	2016-09-23	2019-07-02	拜耳股份公司	N3－环状取代的噻吩并尿嘧啶及其用途
CN117567266B (zh) *	2023-11-07	2024-06-14	康龙化成手性医药技术(宁波)有限公司	一种制备2-甲基环丙羧酸的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL72091A0 (en)	1983-06-20	1984-10-31	Lilly Co Eli	N'-substituted(3-aryl 5-isothiazolyl)urea derivatives
DE4328425A1 (de)	1993-08-24	1995-03-02	Basf Ag	Acylamino-substituierte Isoxazol- bzw. Isothiazolderivate, Verfahren zu deren Herstellung und ihre Verwendung
DK124393D0 (da)	1993-11-03	1993-11-03	Lundbeck & Co As H	Compounds
DE19542372A1 (de) *	1995-11-14	1997-05-15	Bayer Ag	Acylierte 5-Aminoisothiazole
UA60365C2 (uk) *	1998-06-04	2003-10-15	Пфайзер Продактс Інк.	Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
JP3411262B2 (ja) *	1999-08-20	2003-05-26	萬有製薬株式会社	新規スピロ化合物
NZ530782A (en) *	2001-08-06	2005-11-25	Pharmacia Italia S	Aminoisoxazole derivatives active as kinase inhibitors
US20060281803A1 (en) *	2003-09-23	2006-12-14	Lindsley Craig W	Pyrazole modulators of metabotropic glutamate receptors
US7326729B2 (en) *	2004-05-12	2008-02-05	Schering Corporation	CXCR1 and CXCR2 chemokine antagonists
BRPI0515571A (pt) *	2004-09-23	2008-07-29	Pfizer Prod Inc	agonistas de receptor de trombopoetina

2007
- 2007-06-07 CN CN2007800211890A patent/CN101466691B/zh not_active Expired - Fee Related
- 2007-06-07 EP EP07873705A patent/EP2076502B1/en active Active
- 2007-06-07 EA EA200870516A patent/EA014233B1/ru not_active IP Right Cessation
- 2007-06-07 AT AT07873705T patent/ATE509921T1/de active
- 2007-06-07 CA CA2652074A patent/CA2652074C/en not_active Expired - Fee Related
- 2007-06-07 PL PL07873705T patent/PL2076502T3/pl unknown
- 2007-06-07 AU AU2007347428A patent/AU2007347428B2/en not_active Ceased
- 2007-06-07 BR BRPI0712862-2A patent/BRPI0712862A2/pt not_active IP Right Cessation
- 2007-06-07 PT PT07873705T patent/PT2076502E/pt unknown
- 2007-06-07 WO PCT/US2007/070572 patent/WO2008103185A2/en not_active Ceased
- 2007-06-07 MY MYPI20084973A patent/MY148084A/en unknown
- 2007-06-07 NZ NZ573352A patent/NZ573352A/en not_active IP Right Cessation
- 2007-06-07 SI SI200730695T patent/SI2076502T1/sl unknown
- 2007-06-07 UA UAA200813907A patent/UA95480C2/uk unknown
- 2007-06-07 DK DK07873705.3T patent/DK2076502T3/da active
- 2007-06-07 HR HR20110436T patent/HRP20110436T1/hr unknown
- 2007-06-07 RS RS20110336A patent/RS51818B/sr unknown
- 2007-06-07 MX MX2008015485A patent/MX2008015485A/es active IP Right Grant
- 2007-06-07 KR KR1020087029772A patent/KR101051559B1/ko not_active Expired - Fee Related
- 2007-06-07 US US12/300,415 patent/US7960419B2/en active Active
- 2007-06-07 JP JP2009514523A patent/JP5108878B2/ja not_active Expired - Fee Related
- 2007-06-07 ES ES07873705T patent/ES2362949T3/es active Active
- 2007-10-29 CR CR10410A patent/CR10410A/es unknown
2008
- 2008-10-23 ZA ZA200809111A patent/ZA200809111B/xx unknown
- 2008-12-01 IL IL195632A patent/IL195632A/en not_active IP Right Cessation
- 2008-12-02 NO NO20085028A patent/NO341474B1/no not_active IP Right Cessation
- 2008-12-03 EC EC2008008939A patent/ECSP088939A/es unknown
- 2008-12-05 TN TNP2008000506A patent/TNSN08506A1/en unknown
2009
- 2009-01-06 MA MA31553A patent/MA30620B1/fr unknown
2011
- 2011-06-24 CY CY20111100600T patent/CY1111588T1/el unknown

Also Published As

Publication number	Publication date
IL195632A (en)	2013-11-28
NO20085028L (no)	2008-12-02
RS51818B (sr)	2011-12-31
JP5108878B2 (ja)	2012-12-26
WO2008103185A2 (en)	2008-08-28
BRPI0712862A2 (pt)	2012-12-18
KR20090008460A (ko)	2009-01-21
KR101051559B1 (ko)	2011-07-22
TNSN08506A1 (en)	2010-04-14
CN101466691A (zh)	2009-06-24
ECSP088939A (es)	2009-01-30
EP2076502B1 (en)	2011-05-18
DK2076502T3 (da)	2011-07-25
CA2652074A1 (en)	2008-08-28
AU2007347428B2 (en)	2012-02-09
CN101466691B (zh)	2011-07-27
US20090182025A1 (en)	2009-07-16
NZ573352A (en)	2011-10-28
ES2362949T3 (es)	2011-07-15
ATE509921T1 (de)	2011-06-15
UA95480C2 (xx)	2011-08-10
EP2076502A2 (en)	2009-07-08
PT2076502E (pt)	2011-06-07
US7960419B2 (en)	2011-06-14
EA014233B1 (ru)	2010-10-29
IL195632A0 (en)	2009-09-01
MY148084A (en)	2013-02-28
HRP20110436T1 (hr)	2011-08-31
CY1111588T1 (el)	2015-10-07
HK1131984A1 (en)	2010-02-12
PL2076502T3 (pl)	2011-09-30
WO2008103185A3 (en)	2008-10-30
EA200870516A1 (ru)	2009-06-30
CR10410A (es)	2008-11-28
SI2076502T1 (sl)	2011-09-30
MX2008015485A (es)	2009-03-06
CA2652074C (en)	2013-08-06
AU2007347428A1 (en)	2008-08-28
JP2009539874A (ja)	2009-11-19
MA30620B1 (fr)	2009-08-03
NO341474B1 (no)	2017-11-27

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TW200738653A (en)	2007-10-16	Anthranilamide/2-amino-heteroarene carboxamide derivatives
MX2009005798A (es)	2009-08-12	Recuperacion de apoplejia.
TW200639159A (en)	2006-11-16	Treatment of pain
MX2009006325A (es)	2009-07-24	Compuestos de heteroaril-heteroarilo como inhibidores de cdk para el tratamiento de cancer, inflamacion e infecciones virales.
TW200806321A (en)	2008-02-01	New therapeutic combinations for the treatment or prevention of psychotic disorders
MX2010008586A (es)	2010-08-23	Amidas de acido 3-(4-fluorofenil)-3-hidroxi-2-amino-propionico y compuestos relacionados que tienen actividad analgesica.
IL197769A (en)	2013-07-31	The history of morphine, medicinal preparations containing them and their use in the preparation of pain medication
WO2007144889A3 (en)	2008-06-19	Treatment of neurofibromatosis
WO2008130321A3 (en)	2008-12-18	Novel n-tetrahydronaphtalene or 5-heterocyclyl-chromane or 8-heterocyclyl-tetrahydronaphtalene derivatives for the treatment of pain
MX2009010162A (es)	2009-10-12	Metodo para tratar dolor mediado por el receptor cb2.
EA200701086A1 (ru)	2007-12-28	Производные изоксазола, их фармацевтические композиции и способ лечения невропатической боли
DOP2008000064A (es)	2009-01-15	Carboxamidas sustituidas.
UA103767C2 (ru)	2013-11-25	Карбоксамидные соединения для лечения метаболических расстройств