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ZA200710643B - Lipases for pharmaceutical use - Google Patents

Lipases for pharmaceutical use

Info

Publication number
ZA200710643B
ZA200710643B ZA200710643A ZA200710643A ZA200710643B ZA 200710643 B ZA200710643 B ZA 200710643B ZA 200710643 A ZA200710643 A ZA 200710643A ZA 200710643 A ZA200710643 A ZA 200710643A ZA 200710643 B ZA200710643 B ZA 200710643B
Authority
ZA
South Africa
Prior art keywords
lipases
pharmaceutical use
pharmaceutical
Prior art date
Application number
ZA200710643A
Other languages
English (en)
Inventor
Svendsen Allan
Borch Kim
Gregory Peter Colin
Original Assignee
Novozymes As
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As, Solvay Pharm Gmbh filed Critical Novozymes As
Publication of ZA200710643B publication Critical patent/ZA200710643B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • C12N9/20Triglyceride splitting, e.g. by means of lipase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/54Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
ZA200710643A 2005-06-24 2007-12-06 Lipases for pharmaceutical use ZA200710643B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200500929 2005-06-24

Publications (1)

Publication Number Publication Date
ZA200710643B true ZA200710643B (en) 2008-11-26

Family

ID=34956781

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200710643A ZA200710643B (en) 2005-06-24 2007-12-06 Lipases for pharmaceutical use

Country Status (17)

Country Link
US (1) US20090047266A1 (xx)
EP (1) EP1896577A2 (xx)
JP (1) JP2008546394A (xx)
KR (1) KR20080017025A (xx)
CN (1) CN101208429A (xx)
AR (1) AR053634A1 (xx)
AU (1) AU2006261442A1 (xx)
BR (1) BRPI0612274A2 (xx)
CA (1) CA2612648A1 (xx)
IL (1) IL187511A0 (xx)
MX (1) MX2007015472A (xx)
NO (1) NO20080437L (xx)
NZ (1) NZ563693A (xx)
RU (1) RU2007149045A (xx)
TW (1) TW200738256A (xx)
WO (1) WO2006136159A2 (xx)
ZA (1) ZA200710643B (xx)

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DE602005009677D1 (de) 2004-03-22 2008-10-23 Solvay Pharm Gmbh Orale pharmazeutische zusammensetzungen von produkten mit lipase, insbesondere von pankreatin, mit tensiden
EP1896057A2 (en) * 2005-06-24 2008-03-12 Novozymes A/S Amylases for pharmaceutical use
MX2008000850A (es) 2005-07-29 2008-03-18 Solvay Pharm Gmbh Procedimientos para la fabricacion de polvo de pancreatina esterilizada.
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
BRPI0714241A2 (pt) * 2006-07-13 2013-03-12 Dsm Ip Assets Bv uso de uma amilase bacteriana, mÉtodos para preparar uma composiÇço, para aumentar o produÇço de leite de animais da subfamÍlia bovinae, para aumentar a espessura de gordura no dorso de animais da sbufamÍlia bovinae, para aumenantar o ganho de peso e/ou proporÇço de conversço de raÇço de animais da subfamÍlia bovinae, e para melhorar a digestibilidade aparente e/ou desaparecimento de mÁteria seca de gÊneros alimentÍcios em animais da subfamÍlia bovinae, e, uso de uma amilase bacteriana, mÉtodos para preparar uma composiÇço, para aumentar o produÇço de leite de animais da subfamÍlia bovinae, para aumentar a espessura de gordura no dorso de animais da subfamÍlia bovinae, para aumentar o ganho de peso e/ou proporÇço de conversço de raÇço de animais da subfamÍlia bovinae, e para melhorar a digestibilidade aparente e/ou desaparecimento de matÉria seca de gÊneros alimenticÍcios em animais da subfamÍlia bovinae, e, composiÇço
EP2455460A3 (en) 2006-12-21 2012-12-26 Novozymes A/S Lipase variants for pharmaceutical use
JP2011505160A (ja) 2007-12-04 2011-02-24 ノボザイムス アクティーゼルスカブ 医薬用途のためのプロテアーゼ変異体
KR20100101106A (ko) * 2008-01-03 2010-09-16 애보트 프러덕츠 게엠베하 정제 미생물 리파제 과립들을 포함하는 약학 조성물 및 소화 장애들의 예방 또는 치료방법
CN102076355B (zh) 2008-04-29 2014-05-07 Abbvie公司 双重可变结构域免疫球蛋白及其用途
SG191639A1 (en) 2008-06-03 2013-07-31 Abbott Lab Dual variable domain immunoglobulins and uses thereof
AU2009256246B2 (en) 2008-06-03 2013-07-18 Abbvie Inc. Dual variable domain immunoglobulins and uses thereof
GB2468629B (en) * 2008-06-08 2011-10-26 Tarig Sayed Mustafa Arbab Method, composition, device for the treatment of amylase malfunctions/inactivity in association with saccharides (mainly polysaccharides) based diseases
GB2465814B (en) * 2008-06-19 2011-10-26 Tarig Sayed Mustafa Arbab Method,composition and device for the treatment of enzymes and saccharides disorders
AU2009268585C1 (en) 2008-07-08 2014-10-02 Abbvie Inc. Prostaglandin E2 dual variable domain immunoglobulins and uses thereof
WO2011000924A1 (en) 2009-07-03 2011-01-06 Abbott Products Gmbh Spray-dried amylase, pharmaceutical preparations comprising the same and use
US8784884B2 (en) * 2009-09-17 2014-07-22 Stephen Perrett Pancreatic enzyme compositions and methods for treating pancreatitis and pancreatic insufficiency
UY32948A (es) 2009-10-15 2011-02-28 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
UY32979A (es) 2009-10-28 2011-02-28 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
TW201206473A (en) 2010-08-03 2012-02-16 Abbott Lab Dual variable domain immunoglobulins and uses thereof
CN103260639A (zh) 2010-08-26 2013-08-21 Abbvie公司 双重可变结构域免疫球蛋白及其用途
US8268305B1 (en) 2011-09-23 2012-09-18 Bio-Cat, Inc. Method and compositions to reduce serum levels of triacylglycerides in human beings using a fungal lipase
ES2887576T3 (es) * 2011-12-29 2021-12-23 Novozymes As Composiciones detergentes con variantes de lipasa
WO2013102042A2 (en) 2011-12-30 2013-07-04 Abbvie Inc. Dual specific binding proteins directed against il-13 and/or il-17
GB201212932D0 (en) * 2012-07-20 2012-09-05 Dupont Nutrition Biosci Aps Method
GB201212934D0 (en) * 2012-07-20 2012-09-05 Dupont Nutrition Biosci Aps Method
CN103045559B (zh) * 2012-10-23 2014-05-14 浙江工业大学 疏绵状嗜热丝孢菌脂肪酶突变体、编码基因及其应用
CN104797590A (zh) 2012-11-01 2015-07-22 诺维信公司 用于去除dna的方法
HK1212359A1 (en) 2012-11-01 2016-06-10 Abbvie Inc. Anti-vegf/dll4 dual variable domain immunoglobulins and uses thereof
JP2016522793A (ja) 2013-03-15 2016-08-04 アッヴィ・インコーポレイテッド IL−1βおよび/またはIL−17に対して指向された二重特異的結合タンパク質
US10537122B2 (en) * 2013-12-17 2020-01-21 Alltech, Inc. Systems and methods for adjusting animal feed
US9672331B2 (en) * 2013-12-17 2017-06-06 Alltech, Inc. Systems and methods for computer models of animal feed
WO2016094881A2 (en) 2014-12-11 2016-06-16 Abbvie Inc. Lrp-8 binding proteins
TW201710286A (zh) 2015-06-15 2017-03-16 艾伯維有限公司 抗vegf、pdgf及/或其受體之結合蛋白
DE102017104482A1 (de) * 2017-03-03 2018-09-06 Nordmark Arzneimittel Gmbh & Co. Kg Pharmazeutische Zusammensetzung umfassend Pankreatin und einen lipasehaltigen Überzug
WO2019236717A1 (en) * 2018-06-05 2019-12-12 Novozymes Bioag A/S Methods of protecting a plant from insect pests
CN115247166B (zh) * 2021-04-27 2025-11-25 南京百斯杰生物工程有限公司 一种蛋白酶突变体
AU2023272468A1 (en) 2022-05-14 2024-11-14 Novonesis Plant Biosolutions A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections

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DK173590D0 (da) * 1990-06-06 1990-07-19 Novo Nordisk As Rekombinante terapeutiske lipaser
US5869438A (en) * 1990-09-13 1999-02-09 Novo Nordisk A/S Lipase variants
US5892013A (en) * 1990-09-13 1999-04-06 Novo Nordisk A/S Lipase variants
US6495357B1 (en) * 1995-07-14 2002-12-17 Novozyme A/S Lipolytic enzymes
EP1017794A1 (en) * 1997-02-06 2000-07-12 Novo Nordisk A/S Polypeptide-polymer conjugates having added and/or removed attachment groups
JP4723087B2 (ja) * 1998-11-27 2011-07-13 ノボザイムス アクティーゼルスカブ 脂質分解酵素変異体
DK1162995T3 (da) * 1999-03-17 2003-06-23 Solvay Pharm Gmbh Enzymer til behandling af diabetes mellitus type I
AU3420100A (en) * 1999-03-31 2000-10-23 Novozymes A/S Lipase variant
CN100455663C (zh) * 1999-03-31 2009-01-28 诺维信公司 脂肪酶变体
AR032392A1 (es) * 2001-01-19 2003-11-05 Solvay Pharm Gmbh Mezcla de enzimas, preparado farmaceutico y utilizacion de dicho preparado.
DE10260903A1 (de) * 2002-12-20 2004-07-08 Henkel Kgaa Neue Perhydrolasen
US20060251763A1 (en) * 2003-06-19 2006-11-09 Patkar Shamkant A Phospholipase variants

Also Published As

Publication number Publication date
BRPI0612274A2 (pt) 2016-09-06
NO20080437L (no) 2008-03-25
WO2006136159A3 (en) 2007-04-12
US20090047266A1 (en) 2009-02-19
RU2007149045A (ru) 2009-07-10
TW200738256A (en) 2007-10-16
EP1896577A2 (en) 2008-03-12
AR053634A1 (es) 2007-05-09
NZ563693A (en) 2010-08-27
AU2006261442A1 (en) 2006-12-28
CA2612648A1 (en) 2006-12-28
MX2007015472A (es) 2008-04-17
JP2008546394A (ja) 2008-12-25
KR20080017025A (ko) 2008-02-25
CN101208429A (zh) 2008-06-25
WO2006136159A2 (en) 2006-12-28
IL187511A0 (en) 2008-03-20

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