ZA200701399B - Alkylidene tetrahydronaphthalene derivatives, method for their production and their use as anti-inflammatory agents - Google Patents
Alkylidene tetrahydronaphthalene derivatives, method for their production and their use as anti-inflammatory agentsInfo
- Publication number
- ZA200701399B ZA200701399B ZA200701399A ZA200701399A ZA200701399B ZA 200701399 B ZA200701399 B ZA 200701399B ZA 200701399 A ZA200701399 A ZA 200701399A ZA 200701399 A ZA200701399 A ZA 200701399A ZA 200701399 B ZA200701399 B ZA 200701399B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkylidene
- production
- inflammatory agents
- tetrahydronaphthalene derivatives
- tetrahydronaphthalene
- Prior art date
Links
- -1 Alkylidene tetrahydronaphthalene derivatives Chemical class 0.000 title 1
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/84—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004044680A DE102004044680B3 (de) | 2004-09-09 | 2004-09-09 | Alkyliden-Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer sowie diese enthaltende pharmazeutische Präparate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200701399B true ZA200701399B (en) | 2008-09-25 |
Family
ID=35517445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200701399A ZA200701399B (en) | 2004-09-09 | 2007-02-16 | Alkylidene tetrahydronaphthalene derivatives, method for their production and their use as anti-inflammatory agents |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP1786823B1 (xx) |
| JP (1) | JP2008512416A (xx) |
| KR (1) | KR20070050469A (xx) |
| CN (1) | CN101065386A (xx) |
| AR (1) | AR050733A1 (xx) |
| AT (1) | ATE384069T1 (xx) |
| AU (1) | AU2005281859A1 (xx) |
| BR (1) | BRPI0515186A (xx) |
| CA (1) | CA2577861A1 (xx) |
| DE (2) | DE102004044680B3 (xx) |
| EA (1) | EA200700550A1 (xx) |
| EC (1) | ECSP077306A (xx) |
| ES (1) | ES2301056T3 (xx) |
| GT (1) | GT200500241A (xx) |
| IL (1) | IL181832A0 (xx) |
| MX (1) | MX2007002833A (xx) |
| NO (1) | NO20071805L (xx) |
| PA (1) | PA8644701A1 (xx) |
| PE (1) | PE20060596A1 (xx) |
| RS (1) | RS20070095A (xx) |
| SV (1) | SV2006002220A (xx) |
| TW (1) | TW200621703A (xx) |
| UY (1) | UY29109A1 (xx) |
| WO (1) | WO2006027236A1 (xx) |
| ZA (1) | ZA200701399B (xx) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0415209A (pt) | 2003-10-08 | 2006-12-05 | Schering Ag | derivados de tetraidronaftaleno, processo para a produção deles e seu emprego como agentes antiinflamatórios |
| US7662821B2 (en) | 2003-10-08 | 2010-02-16 | Bayer Schering Pharma Ag | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| US7638515B2 (en) | 2003-10-08 | 2009-12-29 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| US20080153859A1 (en) | 2004-04-05 | 2008-06-26 | Hartmut Rehwinkel | Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| DE102004063227A1 (de) * | 2004-12-22 | 2006-07-06 | Schering Ag | Tricylische Aminoalkohole, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| EP1834948A1 (de) | 2006-03-15 | 2007-09-19 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| EP1917963A1 (en) * | 2006-10-31 | 2008-05-07 | Bayer Schering Pharma Aktiengesellschaft | Cyclic phenyl-substituted indazols, a process for their production and their use as anti-inflammatory agents |
| AU2008219115A1 (en) | 2007-02-16 | 2008-08-28 | Synta Pharmaceuticals Corp. | Substituted fused-ring compounds for inflammation and immune-related uses |
| EP2072509A1 (en) | 2007-12-18 | 2009-06-24 | Bayer Schering Pharma Aktiengesellschaft | 1-Aryl-1H-quinoline-2-ones: process for their production and their use as anti-inflammatory agents |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996020930A1 (en) * | 1994-12-29 | 1996-07-11 | Allergan | Acetylenes disubstituted with a 5 or 8 substituted tetrahydronaphthyl or dihydronaphthyl group and with an aryl or heteroaryl groups having retinoid-like biological activity |
| DE10038639A1 (de) * | 2000-07-28 | 2002-02-21 | Schering Ag | Nichtsteroidale Entzündungshemmer |
| DE60318188T2 (de) * | 2002-03-26 | 2008-12-11 | Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield | Glucocorticoid-mimetika, deren herstellung, pharmazeutische zusammensetzungen und verwendung |
| DE10215316C1 (de) * | 2002-04-02 | 2003-12-18 | Schering Ag | Chinolin- und Isochinolin-Derivate, ein pharmazeutisches Mittel und ihre Verwendung als Entzündungshemmer |
| BRPI0415209A (pt) * | 2003-10-08 | 2006-12-05 | Schering Ag | derivados de tetraidronaftaleno, processo para a produção deles e seu emprego como agentes antiinflamatórios |
-
2004
- 2004-09-09 DE DE102004044680A patent/DE102004044680B3/de not_active Expired - Fee Related
-
2005
- 2005-09-02 BR BRPI0515186-4A patent/BRPI0515186A/pt not_active Application Discontinuation
- 2005-09-02 KR KR1020077005549A patent/KR20070050469A/ko not_active Withdrawn
- 2005-09-02 EP EP05786302A patent/EP1786823B1/de not_active Expired - Lifetime
- 2005-09-02 MX MX2007002833A patent/MX2007002833A/es not_active Application Discontinuation
- 2005-09-02 ES ES05786302T patent/ES2301056T3/es not_active Expired - Lifetime
- 2005-09-02 GT GT200500241A patent/GT200500241A/es unknown
- 2005-09-02 DE DE502005002595T patent/DE502005002595D1/de not_active Expired - Fee Related
- 2005-09-02 CN CNA2005800383722A patent/CN101065386A/zh active Pending
- 2005-09-02 CA CA002577861A patent/CA2577861A1/en not_active Abandoned
- 2005-09-02 EA EA200700550A patent/EA200700550A1/ru unknown
- 2005-09-02 RS RSP-2007/0095A patent/RS20070095A/sr unknown
- 2005-09-02 AU AU2005281859A patent/AU2005281859A1/en not_active Abandoned
- 2005-09-02 JP JP2007530646A patent/JP2008512416A/ja not_active Withdrawn
- 2005-09-02 WO PCT/EP2005/009623 patent/WO2006027236A1/de not_active Ceased
- 2005-09-02 AT AT05786302T patent/ATE384069T1/de not_active IP Right Cessation
- 2005-09-06 TW TW094130577A patent/TW200621703A/zh unknown
- 2005-09-08 SV SV2005002220A patent/SV2006002220A/es not_active Application Discontinuation
- 2005-09-08 PE PE2005001041A patent/PE20060596A1/es not_active Application Discontinuation
- 2005-09-08 UY UY29109A patent/UY29109A1/es not_active Application Discontinuation
- 2005-09-08 PA PA20058644701A patent/PA8644701A1/es unknown
- 2005-09-09 AR ARP050103762A patent/AR050733A1/es unknown
-
2007
- 2007-02-16 ZA ZA200701399A patent/ZA200701399B/xx unknown
- 2007-03-08 IL IL181832A patent/IL181832A0/en unknown
- 2007-03-08 EC EC2007007306A patent/ECSP077306A/es unknown
- 2007-04-03 NO NO20071805A patent/NO20071805L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005281859A1 (en) | 2006-03-16 |
| PA8644701A1 (es) | 2006-07-03 |
| AR050733A1 (es) | 2006-11-15 |
| EA200700550A1 (ru) | 2007-10-26 |
| WO2006027236A1 (de) | 2006-03-16 |
| KR20070050469A (ko) | 2007-05-15 |
| BRPI0515186A (pt) | 2008-07-22 |
| EP1786823A1 (de) | 2007-05-23 |
| MX2007002833A (es) | 2007-07-09 |
| CA2577861A1 (en) | 2006-03-16 |
| NO20071805L (no) | 2007-06-07 |
| PE20060596A1 (es) | 2006-07-26 |
| SV2006002220A (es) | 2006-03-15 |
| ES2301056T3 (es) | 2008-06-16 |
| ECSP077306A (es) | 2007-04-26 |
| GT200500241A (es) | 2006-08-17 |
| DE502005002595D1 (de) | 2008-03-06 |
| CN101065386A (zh) | 2007-10-31 |
| IL181832A0 (en) | 2007-07-04 |
| RS20070095A (sr) | 2008-11-28 |
| UY29109A1 (es) | 2006-03-31 |
| TW200621703A (en) | 2006-07-01 |
| EP1786823B1 (de) | 2008-01-16 |
| ATE384069T1 (de) | 2008-02-15 |
| DE102004044680B3 (de) | 2006-06-08 |
| JP2008512416A (ja) | 2008-04-24 |
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