ZA200706783B - Nanoparticulate formulations of docetaxel and analogues thereof - Google Patents
Nanoparticulate formulations of docetaxel and analogues thereofInfo
- Publication number
- ZA200706783B ZA200706783B ZA200706783A ZA200706783A ZA200706783B ZA 200706783 B ZA200706783 B ZA 200706783B ZA 200706783 A ZA200706783 A ZA 200706783A ZA 200706783 A ZA200706783 A ZA 200706783A ZA 200706783 B ZA200706783 B ZA 200706783B
- Authority
- ZA
- South Africa
- Prior art keywords
- docetaxel
- analogues
- nanoparticulate formulations
- nanoparticulate
- formulations
- Prior art date
Links
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 title 1
- 229960003668 docetaxel Drugs 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65593405P | 2005-02-24 | 2005-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200706783B true ZA200706783B (en) | 2008-10-29 |
Family
ID=36928029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200706783A ZA200706783B (en) | 2005-02-24 | 2007-08-15 | Nanoparticulate formulations of docetaxel and analogues thereof |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20060188566A1 (xx) |
| EP (1) | EP1855659A2 (xx) |
| JP (1) | JP2008531591A (xx) |
| KR (1) | KR20080003322A (xx) |
| CN (1) | CN101160118A (xx) |
| AU (1) | AU2006216640A1 (xx) |
| BR (1) | BRPI0608173A2 (xx) |
| CA (1) | CA2598441A1 (xx) |
| EA (1) | EA015987B1 (xx) |
| IL (1) | IL185292A0 (xx) |
| MX (1) | MX2007010394A (xx) |
| NO (1) | NO20074859L (xx) |
| WO (1) | WO2006091780A2 (xx) |
| ZA (1) | ZA200706783B (xx) |
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| KR20140070676A (ko) | 2002-09-06 | 2014-06-10 | 인설트 테라페틱스, 인코퍼레이티드 | 공유결합된 치료제 전달을 위한 사이클로덱스트린-기초 중합체 |
| US20080220074A1 (en) * | 2002-10-04 | 2008-09-11 | Elan Corporation Plc | Gamma radiation sterilized nanoparticulate docetaxel compositions and methods of making same |
| US20050232981A1 (en) * | 2004-04-15 | 2005-10-20 | Ben-Sasson Shmuel A | Compositions capable of facilitating penetration across a biological barrier |
| US20070219131A1 (en) * | 2004-04-15 | 2007-09-20 | Ben-Sasson Shmuel A | Compositions capable of facilitating penetration across a biological barrier |
| US8034765B2 (en) * | 2005-08-31 | 2011-10-11 | Abraxis Bioscience, Llc | Compositions and methods for preparation of poorly water soluble drugs with increased stability |
| HUE042678T2 (hu) * | 2005-08-31 | 2019-07-29 | Abraxis Bioscience Llc | Vízben rosszul oldódó gyógyszerhatóanyagok és antimikrobiális szerek |
| CZ300305B6 (cs) * | 2005-12-20 | 2009-04-15 | Heaton, A. S. | Farmaceutická kompozice obsahující derivát taxanu se zlepšenou terapeutickou úcinností |
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| NZ549831A (en) * | 2006-09-11 | 2009-03-31 | Auckland Uniservices Ltd | Combination of docetaxel and a nitrophenyl phosphate derivative for the treatment of cancer |
| WO2008066899A2 (en) * | 2006-11-28 | 2008-06-05 | Marinus Pharmaceuticals | Nanoparticulate formulations and methods for the making and use thereof |
| JP2010516625A (ja) | 2007-01-24 | 2010-05-20 | インサート セラピューティクス， インコーポレイテッド | 制御された薬物送達のためのテザー基を有するポリマー−薬物コンジュゲート |
| WO2008092084A2 (en) * | 2007-01-26 | 2008-07-31 | Centocor, Inc. | Injectable non-aqueous suspension with high concentration of therapeutic agent |
| WO2008118754A2 (en) * | 2007-03-23 | 2008-10-02 | Elan Corporation Plc | Gamma radiation sterilized nanoparticulate docetaxel compositions and methods for making the same |
| CN101677987A (zh) * | 2007-06-22 | 2010-03-24 | 赛多斯有限责任公司 | 不含吐温80的多西他赛的增溶制剂 |
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-
2006
- 2006-02-24 BR BRPI0608173-8A patent/BRPI0608173A2/pt not_active IP Right Cessation
- 2006-02-24 MX MX2007010394A patent/MX2007010394A/es not_active Application Discontinuation
- 2006-02-24 KR KR1020077021919A patent/KR20080003322A/ko not_active Ceased
- 2006-02-24 US US11/361,055 patent/US20060188566A1/en not_active Abandoned
- 2006-02-24 AU AU2006216640A patent/AU2006216640A1/en not_active Abandoned
- 2006-02-24 WO PCT/US2006/006535 patent/WO2006091780A2/en not_active Ceased
- 2006-02-24 CA CA002598441A patent/CA2598441A1/en not_active Abandoned
- 2006-02-24 JP JP2007557184A patent/JP2008531591A/ja active Pending
- 2006-02-24 EP EP06735983A patent/EP1855659A2/en not_active Withdrawn
- 2006-02-24 EA EA200701793A patent/EA015987B1/ru not_active IP Right Cessation
- 2006-02-24 CN CNA2006800126709A patent/CN101160118A/zh active Pending
-
2007
- 2007-08-15 ZA ZA200706783A patent/ZA200706783B/xx unknown
- 2007-08-15 IL IL185292A patent/IL185292A0/en unknown
- 2007-09-24 NO NO20074859A patent/NO20074859L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EA015987B1 (ru) | 2012-01-30 |
| US20060188566A1 (en) | 2006-08-24 |
| BRPI0608173A2 (pt) | 2010-11-09 |
| AU2006216640A1 (en) | 2006-08-31 |
| EA200701793A1 (ru) | 2008-02-28 |
| KR20080003322A (ko) | 2008-01-07 |
| IL185292A0 (en) | 2008-02-09 |
| WO2006091780A2 (en) | 2006-08-31 |
| CA2598441A1 (en) | 2006-08-31 |
| JP2008531591A (ja) | 2008-08-14 |
| NO20074859L (no) | 2007-11-26 |
| CN101160118A (zh) | 2008-04-09 |
| MX2007010394A (es) | 2008-02-19 |
| WO2006091780A3 (en) | 2007-01-11 |
| EP1855659A2 (en) | 2007-11-21 |
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