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ZA200609237B - CXCR1 and CXCR2 chemokine antagonists - Google Patents

CXCR1 and CXCR2 chemokine antagonists

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Publication number
ZA200609237B
ZA200609237B ZA200609237A ZA200609237A ZA200609237B ZA 200609237 B ZA200609237 B ZA 200609237B ZA 200609237 A ZA200609237 A ZA 200609237A ZA 200609237 A ZA200609237 A ZA 200609237A ZA 200609237 B ZA200609237 B ZA 200609237B
Authority
ZA
South Africa
Prior art keywords
cxcr1
chemokine antagonists
cxcr2 chemokine
cxcr2
antagonists
Prior art date
Application number
ZA200609237A
Other languages
English (en)
Inventor
Chao Jianhua
Cynthia J Aki
Fine Jay
Reggiani Angelo
Arthur G Taveras
Lundell Daniel
Priestley Tony
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ZA200609237B publication Critical patent/ZA200609237B/xx

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    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/36—Nitrogen atoms
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    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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