FI20060188L - Modifioidut IL-4-muteiinin reseptorin antagonistit - Google Patents

Modifioidut IL-4-muteiinin reseptorin antagonistit Download PDF

Info

Publication number: FI20060188L
Authority: FI; Finland
Prior art keywords: modified; receptor antagonists; mutein receptor; mutein; antagonists
Prior art date: 2003-08-29

Application number

FI20060188A

Other languages

English (en)

Swedish (sv)

Other versions

FI20060188A7 (fi

Inventor

Jeffrey Michael Greve

Clark Pan

Steve Roczniak

Stephanie L Yung

Malinda Longphere

Teresa Mo-Fun Wong

Adrian Tomkinson

Original Assignee

Bayer Pharmaceuticals Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-08-29

Filing date

2004-07-20

Publication date

2006-02-24

2004-07-20 Application filed by Bayer Pharmaceuticals Corp filed Critical Bayer Pharmaceuticals Corp

2006-02-24 Publication of FI20060188L publication Critical patent/FI20060188L/fi

2006-04-28 Publication of FI20060188A7 publication Critical patent/FI20060188A7/fi

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2026—IL-4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/45—Toxoplasma
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5406—IL-4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/247—IL-4

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Immunology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Pulmonology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Cell Biology (AREA)
Marine Sciences & Fisheries (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

FI20060188A 2003-08-29 2004-07-20 Modifioidut IL-4-muteiinin reseptorin antagonistit FI20060188A7 (fi)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US49890603P	2003-08-29	2003-08-29
US52822803P	2003-12-09	2003-12-09
US53018203P	2003-12-17	2003-12-17
US10/820,559 US7404957B2 (en)	2003-08-29	2004-04-08	Modified IL-4 mutein receptor antagonists
PCT/US2004/023310 WO2005023860A2 (en)	2003-08-29	2004-07-20	Modified il-4 mutein receptor antagonists

Publications (2)

Publication Number	Publication Date
FI20060188L true FI20060188L (fi)	2006-02-24
FI20060188A7 FI20060188A7 (fi)	2006-04-28

Family

ID=34280052

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI20060188A FI20060188A7 (fi)	2003-08-29	2004-07-20	Modifioidut IL-4-muteiinin reseptorin antagonistit

Country Status (15)

Country	Link
US (1)	US7404957B2 (fi)
EP (1)	EP1660529A2 (fi)
JP (1)	JP4774368B2 (fi)
KR (1)	KR20070008505A (fi)
AU (1)	AU2004270638B2 (fi)
BR (1)	BRPI0413869A (fi)
CA (1)	CA2536586A1 (fi)
CZ (1)	CZ2006206A3 (fi)
DK (1)	DK200600449A (fi)
ES (1)	ES2315146A1 (fi)
FI (1)	FI20060188A7 (fi)
IL (1)	IL173746A0 (fi)
IS (1)	IS8315A (fi)
MX (1)	MXPA06002285A (fi)
WO (1)	WO2005023860A2 (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7785580B2 (en) *	2003-08-29	2010-08-31	Aerovance, Inc.	Modified IL-4 mutein receptor antagonists
KR101241434B1 (ko) *	2004-09-10	2013-03-12	파마오리진 에이피에스	국소 기관, 기관지 또는 폐포의 출혈 또는 객혈의 치료방법
US20070009479A1 (en) *	2005-06-17	2007-01-11	Aerovance, Inc.	Methods for treating dermatitis using mutant human IL-4 compositions
JP2009503105A (ja) *	2005-08-03	2009-01-29	イミュノジェン・インコーポレーテッド	免疫複合体製剤
JP2009525267A (ja) *	2006-01-11	2009-07-09	アエロヴァンスインコーポレイティッド	ヒトおよび非ヒト霊長類において喘息を処置するための方法および組成物
AU2007271349A1 (en) *	2006-07-06	2008-01-10	Apogenix Gmbh	Human IL-4 muteins in combination with chemotherapeutics or pro-apoptotic agents in cancer therapy
EA201070129A1 (ru) *	2007-07-11	2010-10-29	Аэрованс, Инк.	Фармацевтический сухой порошкообразный аэрозольный состав, включающий полипептид, и способ его приготовления
EP2406276A4 (en) *	2009-03-13	2012-12-05	Aerovance Inc	METHOD OF RENATURING RECOMBINANT PROTEINS
EP2580236B1 (en)	2010-06-08	2019-04-03	Pieris Pharmaceuticals GmbH	Tear lipocalin muteins binding il-4 r alpha
WO2015000585A1 (en)	2013-07-02	2015-01-08	Walter Sebald	Muteins of cytokines of the gamma-chain receptor family conjugated to a non-protein group
WO2019148405A1 (zh) *	2018-02-01	2019-08-08	北京凯因科技股份有限公司	IL-4Rα抗体及其用途
EP3553078A1 (en) *	2018-04-11	2019-10-16	Julius-Maximilians-Universität Würzburg	Glyco-engineered interleukin-4 based antagonists

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4423131A1 (de)	1994-07-01	1996-01-04	Bayer Ag	Neue hIL-4-Mutantenproteine als Antagonisten oder partielle Agonisten des humanen Interleukin 4
GB9415379D0 (en) *	1994-07-29	1994-09-21	Smithkline Beecham Plc	Novel compounds
US5986059A (en)	1996-06-14	1999-11-16	Bayer Corporation	T-cell selective interleukin-4 agonists
MY124565A (en) *	1996-07-19	2006-06-30	Bayer Corp	High-affinity interleukin-4-muteins
US6028176A (en) *	1996-07-19	2000-02-22	Bayer Corporation	High-affinity interleukin-4 muteins
CA2296770A1 (en) *	1997-07-14	1999-01-28	Bolder Biotechnology, Inc.	Derivatives of growth hormone and related proteins
US9303613B2 (en)	2012-02-24	2016-04-05	Ford Global Technologies, Llc	Control of vehicle electrical loads during engine auto stop event

2004
- 2004-04-08 US US10/820,559 patent/US7404957B2/en not_active Expired - Fee Related
- 2004-07-20 JP JP2006524657A patent/JP4774368B2/ja not_active Expired - Fee Related
- 2004-07-20 KR KR1020067004147A patent/KR20070008505A/ko not_active Ceased
- 2004-07-20 AU AU2004270638A patent/AU2004270638B2/en not_active Ceased
- 2004-07-20 FI FI20060188A patent/FI20060188A7/fi unknown
- 2004-07-20 MX MXPA06002285A patent/MXPA06002285A/es active IP Right Grant
- 2004-07-20 CA CA002536586A patent/CA2536586A1/en not_active Abandoned
- 2004-07-20 WO PCT/US2004/023310 patent/WO2005023860A2/en not_active Ceased
- 2004-07-20 CZ CZ20060206A patent/CZ2006206A3/cs unknown
- 2004-07-20 ES ES200650017A patent/ES2315146A1/es active Pending
- 2004-07-20 BR BRPI0413869-4A patent/BRPI0413869A/pt not_active IP Right Cessation
- 2004-07-20 EP EP04778687A patent/EP1660529A2/en not_active Withdrawn
2006
- 2006-02-15 IL IL173746A patent/IL173746A0/en unknown
- 2006-02-20 IS IS8315A patent/IS8315A/is unknown
- 2006-03-29 DK DK200600449A patent/DK200600449A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
IL173746A0 (en)	2006-07-05
EP1660529A2 (en)	2006-05-31
KR20070008505A (ko)	2007-01-17
IS8315A (is)	2006-02-20
CZ2006206A3 (cs)	2007-01-10
ES2315146A1 (es)	2009-03-16
JP4774368B2 (ja)	2011-09-14
AU2004270638A1 (en)	2005-03-17
US7404957B2 (en)	2008-07-29
CA2536586A1 (en)	2005-03-17
FI20060188A7 (fi)	2006-04-28
WO2005023860A2 (en)	2005-03-17
BRPI0413869A (pt)	2006-10-24
US20050059590A1 (en)	2005-03-17
JP2007526757A (ja)	2007-09-20
DK200600449A (da)	2006-03-29
AU2004270638B2 (en)	2010-10-07
WO2005023860A3 (en)	2005-06-23
AU2004270638A2 (en)	2005-03-17
MXPA06002285A (es)	2007-03-15

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DK1682142T3 (da)	2012-10-15	M3-muscarin-acetylcholin-receptor-antagonister
ATE450505T1 (de)	2009-12-15	Cb 1 rezeptor inversagonisten
DE60327986D1 (de)	2009-07-30	Sitzstruktur
DE60314931D1 (de)	2007-08-30	Sitzstruktur
ATE382034T1 (de)	2008-01-15	Hydroisoindolin-tachykininrezeptorantagonisten
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DE60332816D1 (de)	2010-07-15	Nk1-antagonisten
FI20060188L (fi)	2006-02-24	Modifioidut IL-4-muteiinin reseptorin antagonistit
NO20043799L (no)	2004-09-10	2-oksasolaminer og deres anvendelse som 5-HT2B reseptor antagonister
ATA2792002A (de)	2003-07-15	Temperaturfühler
DE60328807D1 (de)	2009-09-24	Chimärer antagonist anth1
FR2840006B1 (fr)	2005-01-21	Construction demontable
ATA8202003A (de)	2004-12-15	Hochspannungsmast
DE10255292B4 (de)	2005-04-28	Armlehne
TH105710B (th)	2011-01-26	โอพิออยด์รีเซปเตอร์แอนตะกอนิสต์
EE00339U1 (et)	2003-01-15	Istumisseade
FIU20030323U0 (fi)	2003-09-05	Korotuslattiarakenne
UA7060S (uk)	2003-03-17	Стілець
UA6902S (uk)	2003-01-15	Стілець